| People | Locations | Statistics |
|---|---|---|
| Naji, M. |
| |
| Motta, Antonella |
| |
| Aletan, Dirar |
| |
| Mohamed, Tarek |
| |
| Ertürk, Emre |
| |
| Taccardi, Nicola |
| |
| Kononenko, Denys |
| |
| Petrov, R. H. | Madrid |
|
| Alshaaer, Mazen | Brussels |
|
| Bih, L. |
| |
| Casati, R. |
| |
| Muller, Hermance |
| |
| Kočí, Jan | Prague |
|
| Šuljagić, Marija |
| |
| Kalteremidou, Kalliopi-Artemi | Brussels |
|
| Azam, Siraj |
| |
| Ospanova, Alyiya |
| |
| Blanpain, Bart |
| |
| Ali, M. A. |
| |
| Popa, V. |
| |
| Rančić, M. |
| |
| Ollier, Nadège |
| |
| Azevedo, Nuno Monteiro |
| |
| Landes, Michael |
| |
| Rignanese, Gian-Marco |
|
Devine, Declan
Irish Research Council
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (34/34 displayed)
- 2024Influence of Extrusion Screw Speed and CNT Concentration on the Mechanical and EMI Properties of PC/ABS Based Nanocompositescitations
- 2023Designing Sustainable Polymer Blendscitations
- 2023Investigation of Thermal, Mechanical and Shape Memory Properties of 3D-Printed Functionally Graded Nanocomposite Materialscitations
- 2023Effect of Mechanical Recycling on the Mechanical Properties of PLA-Based Natural Fiber-Reinforced Compositescitations
- 2023Rheological Behaviour of ABS/Metal Composites with Improved Thermal Conductivity for Additive Manufacturingcitations
- 2022Bioresorbable Chitosan-Based Bone Regeneration Scaffold Using Various Bioceramics and the Alteration of Photoinitiator Concentration in an Extended UV Photocrosslinking Reactioncitations
- 2022SMA-Based Haptic Gloves Usage in the Smart Factory Concept: XR Use Casecitations
- 2021Stereolithography (SLA) utilised to print injection mould tooling in order to evaluate thermal and mechanical properties of commercial polypropylenecitations
- 2021Physical properties of shellac material used for hot melt extrusion with potential application in the pharmaceutical industrycitations
- 2021Physical properties of shellac material used for hot melt extrusion with potential application in the pharmaceutical industry
- 2020Effect of stereolithography 3d printing on the properties of pegdma hydrogelscitations
- 2020Fused filament fabrication of peekcitations
- 2020Development of sustainable flexible packaging solutions using novel biodegradable and compostable polymer blends
- 2020Effect of stereolithography 3D printing on the properties of PEGDMA hydrogels.citations
- 2019Electrospun hydrogels composites for bone tissue engineering.
- 2019Comparison of fused-filament fabrication to direct compression and injection molding in the manufacture of oral tabletscitations
- 2019The production of a novel poly(vinyl alcohol) hydrogel cryogenic spheres for immediate release using a droplet systemcitations
- 2019Additive manufacturing of PLA/HNT nanocomposites for biomedical applicationscitations
- 2019Faster release of lumen-loaded drugs than matrix-loaded equivalent in polylactic acid/halloysite nanotubescitations
- 2019Photopolymerization for filling porous ceramic matrixcitations
- 20183D printed end of arm tooling (EOAT) of a robotic arm
- 2018Surface-modified halloysite nanotubes reinforced poly(lactic acid) for use in biodegradable coronary stentscitations
- 2018Material considerations for fused-filament fabrication of solid dosage formscitations
- 2018Electrospun hydrogels composites for bone tissue engineeringcitations
- 2018Degradable nanocomposites for fused filament fabrication applicationscitations
- 2017Halloysite nanotube reinforced polylactic acid compositecitations
- 2016Synthesis and characterization of high density polyethylene/peat ash compositescitations
- 2016Chemical surface modification of calcium carbonate particles with stearic acid using different treating methodscitations
- 2016Melt Extruded Bioresorbable Polymer Composites for Potential Regenerative Medicine Applicationscitations
- 2007Preparation of monolithic matrices for oral drug delivery using a supercritical fluid assisted hot melt extrusion processcitations
- 2007The incorporation of an organically modified layered silicate in monolithic polymeric matrices produced using hot melt extrusioncitations
- 2007The synthesis, swelling behaviour and rheological properties of chemically crosslinked thermosensitive copolymers based on N-isopropylacrylamidecitations
- 2006The use of Agar as a novel filler for monolithic matrices produced using hot melt extrusioncitations
- 2006Lower critical solution temperature control and swelling behaviour of physically crosslinked thermosensitive copolymers based on N-isopropylacrylamidecitations
Places of action
| Organizations | Location | People |
|---|
article
The incorporation of an organically modified layered silicate in monolithic polymeric matrices produced using hot melt extrusion
Abstract
<p>The body of work described in this research paper outlines the use of nanoclay particles as a novel filler material in a hot melt extruded monolithic polymer matrix for oral drug delivery. Several batches of matrix material were prepared with Carvedilol used as the active pharmaceutical ingredient. An organically modified layered silicate was used as the filler material at various levels of inclusion. The resultant matrices were characterised using steady state parallel plate rheometry, differential scanning calorimetry (DSC), atomic force microscopy (AFM), mechanical testing, and dissolution testing. The mechanical analysis indicated that the nanoclay filler incorporation resulted in an increase in all of the mechanical properties of the matrix. Dissolution analysis showed that the presence of the filler particles resulted in a slower release rate of API than for the matrix alone. The results detailed within this paper indicate that nanoclay materials are an interesting prospect for use as filler materials for extended release hot melt produced dosage forms.</p>