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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Witek, Lukasz
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (42/42 displayed)
- 20233D Printing Type 1 Bovine Collagen Scaffolds for Tissue Engineering Applications—Physicochemical Characterization and In Vitro Evaluationcitations
- 2023Engineering 3D Printed Bioceramic Scaffolds to Reconstruct Critical-Sized Calvaria Defects in a Skeletally Immature Pig Modelcitations
- 2023Three-Dimensional Printing Bioceramic Scaffolds Using Direct-Ink-Writing for Craniomaxillofacial Bone Regeneration. citations
- 2022Residual stress estimated by nanoindentation in pontics and abutments of veneered zirconia fixed dental prosthesescitations
- 2022Physiochemical and bactericidal activity evaluationcitations
- 2022Temporary materials used in prosthodonticscitations
- 2022Stability of fatigued and aged ZTA compared to 3Y-TZP and Al2O3 ceramic systemscitations
- 2021Three-Dimensionally-Printed Bioactive Ceramic Scaffoldscitations
- 2021Nanoscale physico-mechanical properties of an aging resistant ZTA compositecitations
- 2021Effect of supplemental acid-etching on the early stages of osseointegrationcitations
- 2021Hydrothermal aging affects the three-dimensional fit and fatigue lifetime of zirconia abutmentscitations
- 2020Comparative analysis of elastomeric die materials for semidirect composite restorations.
- 2020Bone Tissue Engineering in the Growing Calvaria Using Dipyridamole-Coated, Three-Dimensionally-Printed Bioceramic Scaffoldscitations
- 2020Comparative analysis of elastomeric die materials for semidirect composite restorations
- 2020Microstructural, mechanical, and optical characterization of an experimental aging-resistant zirconia-toughened alumina (ZTA) compositecitations
- 2020Assessing osseointegration of metallic implants with boronized surface treatmentcitations
- 2020Aging resistant ZTA composite for dental applicationscitations
- 2019Long-term outcomes of 3D-printed bioactive ceramic scaffolds for regeneration of the pediatric skeleton
- 2019Osteointegrative and microgeometric comparison between micro-blasted and alumina blasting/acid etching on grade II and V titanium alloys (Ti-6Al-4V)citations
- 2019Physical and chemical characterization of synthetic bone mineral ink for robocasting applications
- 2019Dipyridamole Augments Three-Dimensionally Printed Bioactive Ceramic Scaffolds to Regenerate Craniofacial Bonecitations
- 2019Tissue-engineered alloplastic scaffolds for reconstruction of alveolar defectscitations
- 2019Comparative in vitro study of 3D robocasting scaffolds using beta tricalcium phosphate and synthetic bone mineral
- 2019Synergistic effects of implant macrogeometry and surface physicochemical modifications on osseointegrationcitations
- 2019Repair of Critical-Sized Long Bone Defects Using Dipyridamole-Augmented 3D-Printed Bioactive Ceramic Scaffoldscitations
- 2019Nanomechanical and microstructural characterization of a zirconia-toughened alumina composite after agingcitations
- 2019Dipyridamole-loaded 3D-printed bioceramic scaffolds stimulate pediatric bone regeneration in vivo without disruption of craniofacial growth through facial maturitycitations
- 2019Regeneration of a Pediatric Alveolar Cleft Model Using Three-Dimensionally Printed Bioceramic Scaffolds and Osteogenic Agentscitations
- 2018Form and functional repair of long bone using 3D-printed bioactive scaffoldscitations
- 2018Dipyridamole enhances osteogenesis of three-dimensionally printed bioactive ceramic scaffolds in calvarial defectscitations
- 2018Three dimensionally printed bioactive ceramic scaffold osseoconduction across critical-sized mandibular defectscitations
- 2017Controlling calcium and phosphate ion release of 3D printed bioactive ceramic scaffoldscitations
- 2017Biocompatibility and degradation properties of WE43 Mg alloys with and without heat treatmentcitations
- 2017Abstract 47. Dipyridamole-Containing 3D-Printed Bioactive Ceramic Scaffolds for the Treatment of Calvarial Defects
- 2015Geometrical versus Random beta-TCP Scaffolds: Exploring the Effects on Schwann Cell Growth and Behaviorcitations
- 2014The physicochemical characterization and in vivo response of micro/nanoporous bioactive ceramic particulate bone graft materialscitations
- 2014The in vivo effect of P-15 coating on early osseointegrationcitations
- 2013MicroCT analysis of a retrieved root restored with a bonded fiber-reinforced composite dowelcitations
- 2012Physicochemical characterization and in vivo evaluation of amorphous and partially crystalline calcium phosphate coatings fabricated on Ti-6Al-4V implants by the plasma spray methodcitations
- 2012Abutment Design for Implant-Supported Indirect Composite Molar Crownscitations
- 2012Characterization and in vivo evaluation of laser sintered dental endosseous implants in dogscitations
- 2011Additive CAD/CAM process for dental prosthesescitations
Places of action
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article
Three dimensionally printed bioactive ceramic scaffold osseoconduction across critical-sized mandibular defects
Abstract
<p>Background Vascularized bone tissue transfer, commonly used to reconstruct large mandibular defects, is challenged by long operative times, extended hospital stay, donor-site morbidity, and resulting health care. 3D-printed osseoconductive tissue-engineered scaffolds may provide an alternative solution for reconstruction of significant mandibular defects. This pilot study presents a novel 3D-printed bioactive ceramic scaffold with osseoconductive properties to treat segmental mandibular defects in a rabbit model. Methods Full-thickness mandibulectomy defects (12 mm) were created at the mandibular body of eight adult rabbits and replaced by 3D-printed ceramic scaffold made of 100% β-tricalcium phosphate, fit to defect based on computed tomography imaging. After 8 weeks, animals were euthanized, the mandibles were retrieved, and bone regeneration was assessed. Bone growth was qualitatively assessed with histology and backscatter scanning electron microscopy, quantified both histologically and with micro computed tomography and advanced 3D image reconstruction software, and compared to unoperated mandible sections (UMSs). Results Histology quantified scaffold with newly formed bone area occupancy at 54.3 ± 11.7%, compared to UMS baseline bone area occupancy at 55.8 ± 4.4%, and bone area occupancy as a function of scaffold free space at 52.8 ± 13.9%. 3D volume occupancy quantified newly formed bone volume occupancy was 36.3 ± 5.9%, compared to UMS baseline bone volume occupancy at 33.4 ± 3.8%, and bone volume occupancy as a function of scaffold free space at 38.0 ± 15.4%. Conclusions 3D-printed bioactive ceramic scaffolds can restore critical mandibular segmental defects to levels similar to native bone after 8 weeks in an adult rabbit, critical sized, mandibular defect model.</p>