Materials Map

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The Materials Map is an open tool for improving networking and interdisciplinary exchange within materials research. It enables cross-database search for cooperation and network partners and discovering of the research landscape.

The dashboard provides detailed information about the selected scientist, e.g. publications. The dashboard can be filtered and shows the relationship to co-authors in different diagrams. In addition, a link is provided to find contact information.

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The Materials Map is still under development. In its current state, it is only based on one single data source and, thus, incomplete and contains duplicates. We are working on incorporating new open data sources like ORCID to improve the quality and the timeliness of our data. We will update Materials Map as soon as possible and kindly ask for your patience.

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in Cooperation with on an Cooperation-Score of 37%

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Publications (28/28 displayed)

  • 2023Broadband scattering properties of articular cartilage zones and their relationship with the heterogenous structure of articular cartilage extracellular matrix5citations
  • 2021Infrared fiber-optic spectroscopy detects bovine articular cartilage degeneration14citations
  • 2020Comparison of water, hydroxyproline, uronic acid and elastin contents of bovine knee ligaments and patellar tendon and their relationships with biomechanical properties20citations
  • 2019T2* and quantitative susceptibility mapping in an equine model of post-traumatic osteoarthritis: assessment of mechanical and structural properties of articular cartilagecitations
  • 2019T2* and quantitative susceptibility mapping in an equine model of post-traumatic osteoarthritis: assessment of mechanical and structural properties of articular cartilage15citations
  • 2019Arthroscopic determination of cartilage proteoglycan content and collagen network structure with near-infrared spectroscopy34citations
  • 2019Effects of body mass on microstructural features of the osteochondral unit: A comparative analysis of 37 mammalian species16citations
  • 2018Quantitative susceptibility mapping of articular cartilage: ex vivo findings at multiple orientations and following different degradation treatments23citations
  • 2017Contrast-enhanced computed tomography enables quantitative evaluation of tissue properties at intrajoint regions in cadaveric knee cartilage22citations
  • 2017Corrigendum to “Multimodality scoring of chondral injuries in the equine fetlock joint ex vivo” [Osteoarthritis Cartilage 25 (5) (2017 May) 790–798] (S1063458416304666), (10.1016/j.joca.2016.12.007))1citations
  • 2017Tissue viscoelasticity is related to tissue composition but may not fully predict the apparent-level viscoelasticity in human trabecular bone – an experimental and finite element study26citations
  • 2016Differences in acoustic impedance of fresh and embedded human trabecular bone samples - scanning acoustic microscopy and numerical evaluation7citations
  • 2015Ultrasound backscattering is anisotropic in bovine articular cartilage7citations
  • 2015Inter-individual changes in cortical bone three-dimensional microstructure and elastic coefficient have opposite effects on radial sound speed4citations
  • 2014Deformation of articular cartilage during static loading of a knee joint - experimental and finite element analysis104citations
  • 2013New disposable forehead electrode set with excellent signal quality and imaging compatibility24citations
  • 2007Effect of human trabecular bone composition on its electrical properties45citations
  • 2006Interrelationships between electrical properties and microstructure of human trabecular bone40citations
  • 2006T2 relaxation time mapping reveals age- and species-related diversity of collagen network architecture in articular cartilage104citations
  • 2006Collagen network primarily controls poisson's ratio of bovine articular cartilage in compression133citations
  • 2005Prediction of mechanical properties of human trabecular bone by electrical measurements52citations
  • 2005Improvement of arthroscopic cartilage stiffness probe using amorphous diamond coating8citations
  • 2004Prediction of biomechanical properties of articular cartilage with quantitative magnetic resonance imaging116citations
  • 2003Structure-function relationships in enzymatically modified articular cartilage118citations
  • 2003Electrical and dielectric properties of bovine trabecular bone - Relationships with mechanical properties and mineral density50citations
  • 2002Ultrasonic characterization of articular cartilagecitations
  • 2002Comparison of the equilibrium response of articular cartilage in unconfined compression, confined compression and indentation369citations
  • 2000Quantitative MR microscopy of enzymatically degraded articular cartilagecitations

Places of action

Chart of shared publication
Mirhashemi, Arash
1 / 1 shared
Paakkari, Petri
1 / 1 shared
Kienle, Alwin
1 / 1 shared
Foschum, Florian
1 / 1 shared
Nippolainen, Ervin
2 / 2 shared
Kafian-Attari, Iman
1 / 1 shared
George, Akuroma
1 / 1 shared
Bergmann, Florian
1 / 1 shared
Afara, Isaac
5 / 5 shared
Zimmermann, Boris
1 / 2 shared
Kohler, Achim
1 / 2 shared
Saarakkala, Simo
3 / 5 shared
Virtanen, Vesa
1 / 1 shared
Shaikh, Rubina
1 / 1 shared
Solheim, Johanne
1 / 1 shared
Tafintseva, Valeria
1 / 1 shared
Rieppo, Lassi
2 / 3 shared
Torniainen, Jari
1 / 1 shared
Ristaniemi, A.
1 / 1 shared
Stenroth, L.
1 / 1 shared
Finnilä, M. A. J.
1 / 1 shared
Korhonen, R. K.
5 / 6 shared
Paakkonen, T.
1 / 1 shared
Visser, Jetze
2 / 5 shared
Nykänen, Olli
3 / 4 shared
Te Moller, Nikae C. R.
1 / 1 shared
Nissi, Mikko J.
2 / 3 shared
Ketola, Juuso H.
1 / 1 shared
Sarin, Jaakko K.
2 / 3 shared
Mancini, Irina A. D.
2 / 3 shared
Brommer, Harold
2 / 5 shared
Tiitu, Virpi
4 / 4 shared
Malda, Jos
2 / 39 shared
Leskinen, Henri
1 / 1 shared
René Van Weeren, P.
1 / 1 shared
Sarin, J. K.
2 / 3 shared
Leskinen, H.
1 / 2 shared
Brommer, H.
2 / 3 shared
Visser, J.
1 / 4 shared
Mancini, I. A. D.
2 / 2 shared
Nissi, M. J.
2 / 3 shared
Tiitu, V.
1 / 2 shared
Te Moller, N. C. R.
1 / 1 shared
Van Weeren, P. R.
2 / 4 shared
Ketola, J. H.
1 / 2 shared
Malda, J.
2 / 6 shared
Nykänen, O.
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Van Weeren, P. René
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Rieppo, L.
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Van Rijen, M. H. P.
1 / 1 shared
Weinans, H.
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Pouran, B.
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Kik, M.
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Braganca, F. M. Serra
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Shmueli, Karin
1 / 1 shared
Kolehmainen, Ville
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Snyder, Brian D.
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Joukainen, Antti
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Jurvelin, Jukka S.
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Kokkonen, Harri T.
1 / 1 shared
Honkanen, Juuso T. J.
1 / 1 shared
Stewart, Rachel C.
1 / 1 shared
Grinstaff, Mark W.
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Puhakka, P. H.
1 / 1 shared
Inkinen, S. I.
1 / 1 shared
Argüelles, D.
1 / 1 shared
Saarakkala, S.
2 / 5 shared
Jurvelin, J. S.
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Tanska, P.
1 / 1 shared
Ojanen, X.
1 / 1 shared
Isaksson, H.
1 / 1 shared
Magnusson, S. P.
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Malo, M. K. H.
1 / 1 shared
Koistinen, A. P.
1 / 1 shared
Väänänen, S. P.
1 / 1 shared
Grassi, L.
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Ribel-Madsen, S. M.
1 / 1 shared
Isaksson, Hanna
1 / 17 shared
Inkinen, Satu I.
2 / 2 shared
Ojanen, Xiaowei
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Malo, Markus K. H.
2 / 2 shared
Virén, Tuomas
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Liukkonen, Jukka
2 / 2 shared
Eneh, Chibuzor T. M.
1 / 1 shared
Salo, J.
1 / 3 shared
Mononen, M. E.
1 / 1 shared
Halonen, K. S.
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Mervaala, Esa
1 / 1 shared
Myllymaa, Sami
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Myllymaa, Katja
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Lappalainen, Reijo
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Lepola, Pasi
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Hukkanen, Taina
1 / 1 shared
Hakulinen, M. A.
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Lammi, M. J.
1 / 1 shared
Sierpowska, J.
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Lappalainen, R.
4 / 8 shared
Day, J. S.
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Kiviranta, I.
2 / 3 shared
Laasanen, M. S.
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Nieminen, M. T.
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Rieppo, J.
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Rieppo, Jarno
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Korhonen, Rami K.
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Kiviranta, Panu
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Julkunen, Petro
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Voutilainen, Tanja
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Nieminen, Miika T.
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Helminen, Heikki J.
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Laasanen, Mikko S.
1 / 1 shared
Silvennoinen, Johanna
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Kovanen, Vuokko
1 / 2 shared
Hyttinen, Mika M.
1 / 1 shared
Sierpowska, Joanna
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Helminen, H. J.
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Nieminen, H. J.
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Hirvonen, J.
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Hakumäki, Juhana M.
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Chart of publication period
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Co-Authors (by relevance)

  • Mirhashemi, Arash
  • Paakkari, Petri
  • Kienle, Alwin
  • Foschum, Florian
  • Nippolainen, Ervin
  • Kafian-Attari, Iman
  • George, Akuroma
  • Bergmann, Florian
  • Afara, Isaac
  • Zimmermann, Boris
  • Kohler, Achim
  • Saarakkala, Simo
  • Virtanen, Vesa
  • Shaikh, Rubina
  • Solheim, Johanne
  • Tafintseva, Valeria
  • Rieppo, Lassi
  • Torniainen, Jari
  • Ristaniemi, A.
  • Stenroth, L.
  • Finnilä, M. A. J.
  • Korhonen, R. K.
  • Paakkonen, T.
  • Visser, Jetze
  • Nykänen, Olli
  • Te Moller, Nikae C. R.
  • Nissi, Mikko J.
  • Ketola, Juuso H.
  • Sarin, Jaakko K.
  • Mancini, Irina A. D.
  • Brommer, Harold
  • Tiitu, Virpi
  • Malda, Jos
  • Leskinen, Henri
  • René Van Weeren, P.
  • Sarin, J. K.
  • Leskinen, H.
  • Brommer, H.
  • Visser, J.
  • Mancini, I. A. D.
  • Nissi, M. J.
  • Tiitu, V.
  • Te Moller, N. C. R.
  • Van Weeren, P. R.
  • Ketola, J. H.
  • Malda, J.
  • Nykänen, O.
  • Van Weeren, P. René
  • Rieppo, L.
  • Van Rijen, M. H. P.
  • Weinans, H.
  • Pouran, B.
  • Kik, M.
  • Braganca, F. M. Serra
  • Shmueli, Karin
  • Kolehmainen, Ville
  • Snyder, Brian D.
  • Joukainen, Antti
  • Jurvelin, Jukka S.
  • Kokkonen, Harri T.
  • Honkanen, Juuso T. J.
  • Stewart, Rachel C.
  • Grinstaff, Mark W.
  • Puhakka, P. H.
  • Inkinen, S. I.
  • Argüelles, D.
  • Saarakkala, S.
  • Jurvelin, J. S.
  • Tanska, P.
  • Ojanen, X.
  • Isaksson, H.
  • Magnusson, S. P.
  • Malo, M. K. H.
  • Koistinen, A. P.
  • Väänänen, S. P.
  • Grassi, L.
  • Ribel-Madsen, S. M.
  • Isaksson, Hanna
  • Inkinen, Satu I.
  • Ojanen, Xiaowei
  • Malo, Markus K. H.
  • Virén, Tuomas
  • Liukkonen, Jukka
  • Eneh, Chibuzor T. M.
  • Salo, J.
  • Mononen, M. E.
  • Halonen, K. S.
  • Mervaala, Esa
  • Myllymaa, Sami
  • Myllymaa, Katja
  • Lappalainen, Reijo
  • Lepola, Pasi
  • Hukkanen, Taina
  • Hakulinen, M. A.
  • Lammi, M. J.
  • Sierpowska, J.
  • Lappalainen, R.
  • Day, J. S.
  • Kiviranta, I.
  • Laasanen, M. S.
  • Nieminen, M. T.
  • Rieppo, J.
  • Rieppo, Jarno
  • Korhonen, Rami K.
  • Kiviranta, Panu
  • Julkunen, Petro
  • Voutilainen, Tanja
  • Nieminen, Miika T.
  • Helminen, Heikki J.
  • Laasanen, Mikko S.
  • Silvennoinen, Johanna
  • Kovanen, Vuokko
  • Hyttinen, Mika M.
  • Sierpowska, Joanna
  • Helminen, H. J.
  • Nieminen, H. J.
  • Hirvonen, J.
  • Hakumäki, Juhana M.
OrganizationsLocationPeople

article

T2* and quantitative susceptibility mapping in an equine model of post-traumatic osteoarthritis: assessment of mechanical and structural properties of articular cartilage

  • Sarin, J. K.
  • Töyräs, Juha
  • Leskinen, H.
  • Brommer, H.
  • Visser, J.
  • Mancini, I. A. D.
  • Nissi, M. J.
  • Tiitu, V.
  • Te Moller, N. C. R.
  • Van Weeren, P. R.
  • Ketola, J. H.
  • Malda, J.
  • Nykänen, O.
Abstract

Objective: To investigate the potential of quantitative susceptibility mapping (QSM) and T2* relaxation time mapping to determine mechanical and structural properties of articular cartilage via univariate and multivariate analysis. Methods: Samples were obtained from a cartilage repair study, in which surgically induced full-thickness chondral defects in the stifle joints of seven Shetland ponies caused post-traumatic osteoarthritis (14 samples). Control samples were collected from non-operated joints of three animals (6 samples). Magnetic resonance imaging (MRI) was performed at 9.4 T, using a 3-D multi-echo gradient echo sequence. Biomechanical testing, digital densitometry (DD) and polarized light microscopy (PLM) were utilized as reference methods. To compare MRI parameters with reference parameters (equilibrium and dynamic moduli, proteoglycan content, collagen fiber angle and -anisotropy), depth-wise profiles of MRI parameters were acquired at the biomechanical testing locations. Partial least squares regression (PLSR) and Spearman's rank correlation were utilized in data analysis. Results: PLSR indicated a moderate-to-strong correlation (ρ = 0.49–0.66) and a moderate correlation (ρ = 0.41–0.55) between the reference values and T2* relaxation time and QSM profiles, respectively (excluding superficial-only results). PLSR correlations were noticeably higher than direct correlations between bulk MRI and reference parameters. 3-D parametric surface maps revealed spatial variations in the MRI parameters between experimental and control groups. Conclusion: Quantitative parameters from 3-D multi-echo gradient echo MRI can be utilized to predict the properties of articular cartilage. With PLSR, especially the T2* relaxation time profile appeared to correlate with the properties of cartilage. Furthermore, the results suggest that degeneration affects the QSM-contrast in the cartilage. However, this change in contrast is not easy to quantify.

Topics
  • impedance spectroscopy
  • surface
  • defect
  • susceptibility
  • Polarized light microscopy