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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Silva, N. A.
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (20/20 displayed)
- 2022Multi-material cellular structured orthopedic implants design: In vitro and bio-tribological performancecitations
- 201845S5 BAG-Ti6Al4V structurescitations
- 2016Unveiling the effects of the secretome of mesenchymal progenitors from the umbilical cord in different neuronal cell populations (vol 95, pg 2297, 2013)citations
- 2016Erratum: Microglia Response and in Vivo Therapeutic Potential of Methylprednisolone-Loaded Dendrimer Nanoparticles in Spinal Cord Injury (Small (2013) 9 (738-749) DOI: 10.1002/smll.201201888)citations
- 2015Hierarchical scaffolds enhance osteogenic differentiation of human Wharton's jelly derived stem cellscitations
- 2014From basics to clinical: A comprehensive review on spinal cord injurycitations
- 2013Tissue engineering and regenerative medicine: Past, present, and futurecitations
- 2013Modulation of bone marrow mesenchymal stem cell secretome by ECM-like hydrogelscitations
- 2013Development and characterization of a PHB-HV-based 3D scaffold for a tissue engineering and cell-therapy combinatorial approach for spinal cord injury regenerationcitations
- 2013Combining adult stem cells and olfactory ensheathing cells: The secretome effectcitations
- 2013Benefits of spine stabilization with biodegradable scaffolds in spinal cord injured ratscitations
- 2013Unveiling the effects of the secretome of mesenchymal progenitors from the umbilical cord in different neuronal cell populationscitations
- 2013Microglia response and in vivo therapeutic potential of methylprednisolone-loaded dendrimer nanoparticles in spinal cord injurycitations
- 2012Interactions between Schwann and olfactory ensheathing cells with a starch/polycaprolactone scaffold aimed at spinal cord injury repaircitations
- 2012Peripheral mineralization of a 3D biodegradable tubular construct as a way to enhance guidance stabilization in spinal cord injury regenerationcitations
- 2012Using the secretome of mesenchymal progenitors of the umbilical cord as a modulator of neural and glial survival, viability and differentiation
- 2012The effects of peptide modified gellan gum and olfactory ensheathing glia cells on neural stem/progenitor cell fatecitations
- 2011The secretome of bone marrow mesenchymal stem cells-conditioned media varies with time and drives a distinct effect on mature neurons and glial cells (primary cultures)citations
- 2010Development and characterization of a novel hybrid tissue engineering-based scaffold for spinal cord injury repaircitations
- 2008Starch/gellan gum hybrid 3D guidance systems for spinal cord injury regeneration: Scaffolds processing, characterization and biological evaluation
Places of action
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article
Multi-material cellular structured orthopedic implants design: In vitro and bio-tribological performance
Abstract
<p>In this study, Selective Laser Melting (SLM) was used to produce mono-material Ti64Al4V- and NiTi-cubic cellular structures with an open-cell size and wall thickness of 500 μm and 100 μm, respectively. Bioactive beta-tricalcium phosphate (βTCP) and polymer poly-ether-ether ketone (PEEK) were used to fill the produced structures open-cells, thus creating multi-material components. These structures were characterized in vitro in terms of cell viability, adhesion, differentiation and mineralization. Also, bio-tribological experiments were performed against bovine plate to mimic the moment of implant insertion. Results revealed that metabolic activity and mineralization were improved on SLM mono-material groups, when compared to the control group. All cell metrics were improved with the addition of PEEK, conversely to βTCP where no significant differences were found. These results suggest that the proposed solutions can be used to improve implants performance.</p>