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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Watson, Timothy F.
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Topics
Publications (17/17 displayed)
- 2018In-vitro subsurface remineralisation of artificial enamel white spot lesions pre-treated with chitosan
- 2018Remineralisation of enamel white spot lesions pre-treated with chitosan in the presence of salivary pelliclecitations
- 2015Surface pre-conditioning with bioactive glass air-abrasion can enhance enamel white spot lesion remineralizationcitations
- 2014Enamel white spot lesions can remineralise using bio-active glass and polyacrylic acid-modified bio-active glass powderscitations
- 2013Experimental etch-and-rinse adhesives doped with bioactive calcium silicate-based micro-fillers to generate therapeutic resin-dentin interfacescitations
- 2012Adhesion of Indirect MOD Resin Composite Inlays Luted With Self-adhesive and Self-etching Resin Cementscitations
- 2012Influence of air-abrasion executed with polyacrylic acid-Bioglass 45S5 on the bonding performance of a resin-modified glass ionomer cementcitations
- 2011An in vitro evaluation of selective demineralised enamel removal using bio-active glass air abrasioncitations
- 2011Minimally invasive caries removal using bio-active glass air-abrasioncitations
- 2011Durability of Resin Cement Bond to Aluminium Oxide and Zirconia Ceramics after Air Abrasion and Laser Treatmentcitations
- 2010Flexural strength of glass fibre-reinforced posts bonded to dual-cure composite resin cementscitations
- 2009Y-TZP Ceramics: Key Concepts for Clinical Applicationcitations
- 2009Bond Strength of Resin Cements to a Zirconia Ceramic with Different Surface Treatmentscitations
- 2009An in vitro evaluation of the efficiency of an air-abrasion system using helium as a propellantcitations
- 2009Evaluation of the Surface Roughness and Morphologic Features of Y-TZP Ceramics after Different Surface Treatmentscitations
- 2008An in vitro investigation of the effect and retention of bioactive glass air-abrasive on sound and carious dentinecitations
- 2006Microhardness as a predictor of sound and carious dentine removal using alumina air abrasioncitations
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article
Remineralisation of enamel white spot lesions pre-treated with chitosan in the presence of salivary pellicle
Abstract
Objective To investigate the remineralisation of chitosan pre-treated enamel white spot lesions (WSLs) by bioglass in the presence of the pellicle layer.Methods50 artificial enamel white spot lesions were created by acidic gel. Two lesions were used to investigate the formation of the pellicle layer by treating with human whole saliva for 3 min. 48 lesions were assigned to 6 experimental groups (n = 8): (1) bioactive glass slurry, (2) bioactive glass containing polyacrylic acid (BG + PAA) slurry, (3) chitosan pre-treated WSLs with BG slurry (CS-BG), (4) chitosan pre-treated WSLs with BG + PAA slurry (CS-BG + PAA), (5) “standard” remineralisation solution (RS) and (6) de-ionised water (negative control, NC). Remineralisation was carried out using a pH-cycling model for 7 days. Before each treatment using remineralising agents, 3-min pellicle was formed on lesions’ surfaces. Mineral content changes, surface and subsurface microhardness and ultrastructure were evaluated by Raman intensity mapping, Knoop microhardness and scanning electron microscopy, respectively. Data were statistically analysed using one-way ANOVA with Tukey’s test (p < 0.05 is considered as significant).ResultsDespite the heterogeneously formed pellicle layer, all groups showed an increase in surface mineral content after pH-cycling. Chitosan pre-treatment enhanced the subsurface remineralisation of WSLs using bioglass as both pre-treated groups showed greater surface and subsurface microhardness compared to NC. CS-BG exhibited denser subsurface structure than BG, while in CS-BG + PAA the crystals were bigger in size but resemble more enamel-like compared to BG + PAA as shown in SEM observations. Remineralisation of RS was limited to the surface as no significant subsurface changes of mechanical properties and structure were found.ConclusionsChitosan pre-treatment can enhance WSL remineralisation with bioglass biomaterials when a short-term salivary pellicle is present. A further investigation using a long-term pH-cycling model with mature pellicle is suggested with regards to clinical application.Clinical significanceChitosan pre-treatment has the potential in clinical application to remineralise subsurface lesions to achieve lesion consolidation.