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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Töyräs, Juha
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (28/28 displayed)
- 2023Broadband scattering properties of articular cartilage zones and their relationship with the heterogenous structure of articular cartilage extracellular matrixcitations
- 2021Infrared fiber-optic spectroscopy detects bovine articular cartilage degenerationcitations
- 2020Comparison of water, hydroxyproline, uronic acid and elastin contents of bovine knee ligaments and patellar tendon and their relationships with biomechanical propertiescitations
- 2019T2* and quantitative susceptibility mapping in an equine model of post-traumatic osteoarthritis: assessment of mechanical and structural properties of articular cartilage
- 2019T2* and quantitative susceptibility mapping in an equine model of post-traumatic osteoarthritis: assessment of mechanical and structural properties of articular cartilagecitations
- 2019Arthroscopic determination of cartilage proteoglycan content and collagen network structure with near-infrared spectroscopycitations
- 2019Effects of body mass on microstructural features of the osteochondral unit: A comparative analysis of 37 mammalian speciescitations
- 2018Quantitative susceptibility mapping of articular cartilage: ex vivo findings at multiple orientations and following different degradation treatmentscitations
- 2017Contrast-enhanced computed tomography enables quantitative evaluation of tissue properties at intrajoint regions in cadaveric knee cartilagecitations
- 2017Corrigendum to “Multimodality scoring of chondral injuries in the equine fetlock joint ex vivo” [Osteoarthritis Cartilage 25 (5) (2017 May) 790–798] (S1063458416304666), (10.1016/j.joca.2016.12.007))citations
- 2017Tissue viscoelasticity is related to tissue composition but may not fully predict the apparent-level viscoelasticity in human trabecular bone – an experimental and finite element studycitations
- 2016Differences in acoustic impedance of fresh and embedded human trabecular bone samples - scanning acoustic microscopy and numerical evaluationcitations
- 2015Ultrasound backscattering is anisotropic in bovine articular cartilagecitations
- 2015Inter-individual changes in cortical bone three-dimensional microstructure and elastic coefficient have opposite effects on radial sound speedcitations
- 2014Deformation of articular cartilage during static loading of a knee joint - experimental and finite element analysiscitations
- 2013New disposable forehead electrode set with excellent signal quality and imaging compatibilitycitations
- 2007Effect of human trabecular bone composition on its electrical propertiescitations
- 2006Interrelationships between electrical properties and microstructure of human trabecular bonecitations
- 2006T2 relaxation time mapping reveals age- and species-related diversity of collagen network architecture in articular cartilagecitations
- 2006Collagen network primarily controls poisson's ratio of bovine articular cartilage in compressioncitations
- 2005Prediction of mechanical properties of human trabecular bone by electrical measurementscitations
- 2005Improvement of arthroscopic cartilage stiffness probe using amorphous diamond coatingcitations
- 2004Prediction of biomechanical properties of articular cartilage with quantitative magnetic resonance imagingcitations
- 2003Structure-function relationships in enzymatically modified articular cartilagecitations
- 2003Electrical and dielectric properties of bovine trabecular bone - Relationships with mechanical properties and mineral densitycitations
- 2002Ultrasonic characterization of articular cartilage
- 2002Comparison of the equilibrium response of articular cartilage in unconfined compression, confined compression and indentationcitations
- 2000Quantitative MR microscopy of enzymatically degraded articular cartilage
Places of action
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article
Deformation of articular cartilage during static loading of a knee joint - experimental and finite element analysis
Abstract
Novel conical beam CT-scanners offer high resolution imaging of knee structures with i.a. contrast media, even under weight bearing. With this new technology, we aimed to determine cartilage strains and meniscal movement in a human knee at 0, 1, 5, and 30. min of standing and compare them to the subject-specific 3D finite element (FE) model. The FE model of the volunteer's knee, based on the geometry obtained from magnetic resonance images, was created to simulate the creep. The effects of collagen fibril network stiffness, nonfibrillar matrix modulus, permeability and fluid flow boundary conditions on the creep response in cartilage were investigated. In the experiment, 80% of the maximum strain in cartilage developed immediately, after which the cartilage continued to deform slowly until the 30. min time point. Cartilage strains and meniscus movement obtained from the FE model matched adequately with the experimentally measured values. Reducing the fibril network stiffness increased the mean strains substantially, while the creep rate was primarily influenced by an increase in the nonfibrillar matrix modulus. Changing the initial permeability and preventing fluid flow through noncontacting surfaces had a negligible effect on cartilage strains. The present results improve understanding of the mechanisms controlling articular cartilage strains and meniscal movements in a knee joint under physiological static loading. Ultimately a validated model could be used as a noninvasive diagnostic tool to locate cartilage areas at risk for degeneration.