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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Prof
Graz University of Technology
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (18/18 displayed)
- 2024Films based on TEMPO-oxidized chitosan nanoparticles
- 20233D-Printed Anisotropic Nanofiber Composites with Gradual Mechanical Propertiescitations
- 2022Organic acid cross-linked 3D printed cellulose nanocomposite bioscaffolds with controlled porosity, mechanical strength, and biocompatibilitycitations
- 2022Solid Phase Peptide Synthesis on Chitosan Thin Filmscitations
- 2021High oxygen barrier chitosan films neutralized by alkaline nanoparticlescitations
- 2021Design, Characterisation and Applications of Cellulose-Based Thin Films, Nanofibers and 3D Printed Structures
- 2020Design of stable and new polysaccharide nanoparticles composite and their interaction with solid cellulose surfacescitations
- 2019Novel Chitosan–Mg(OH)2-Based Nanocomposite Membranes for Direct Alkaline Ethanol Fuel Cellscitations
- 2019Affinity of Serum Albumin and Fibrinogen to Cellulose, Its Hydrophobic Derivatives and Blendscitations
- 2018Modification of cellulose thin films with lysine moietiescitations
- 2017Interaction of tissue engineering substrates with serum proteins and its influence on human primary endothelial cellscitations
- 2015Cellulose thin films from ionic liquid solutions
- 2014Preparation of PDMS ultrathin films and patterned surface modification with cellulosecitations
- 2014A study on the interaction of cationized chitosan with cellulose surfacescitations
- 2013Functional patterning of biopolymer thin films using enzymes and lithographic methodscitations
- 2013Chemical modification and characterization of poly(ethylene terephthalate) surfaces for collagen immobilizationcitations
- 2012Adsorption of carboxymethyl cellulose on polymer surfacescitations
- 2011Wettability and surface composition of partly and fully regenerated cellulose thin films from trimethylsilyl cellulosecitations
Places of action
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article
Organic acid cross-linked 3D printed cellulose nanocomposite bioscaffolds with controlled porosity, mechanical strength, and biocompatibility
Abstract
<p>Herein, we fabricated chemically cross-linked polysaccharide-based three-dimensional (3D) porous scaffolds using an ink composed of nanofibrillated cellulose, carboxymethyl cellulose, and citric acid (CA), featuring strong shear thinning behavior and adequate printability. Scaffolds were produced by combining direct-ink-writing 3D printing, freeze-drying, and dehydrothermal heat-assisted cross-linking techniques. The last step induces a reaction of CA. Degree of cross-linking was controlled by varying the CA concentration (2.5-10.0 wt.%) to tune the structure, swelling, degradation, and surface properties (pores: 100-450 μm, porosity: 86%) of the scaffolds in the dry and hydrated states. Compressive strength, elastic modulus, and shape recovery of the cross-linked scaffolds increased significantly with increasing cross-linker concentration. Cross-linked scaffolds promoted clustered cell adhesion and showed no cytotoxic effects as determined by the viability assay and live/dead staining with human osteoblast cells. The proposed method can be extended to all polysaccharide-based materials to develop cell-friendly scaffolds suitable for tissue engineering applications.</p>