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| Naji, M. |
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Ahmad, Maqsood
in Cooperation with on an Cooperation-Score of 37%
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Publications (6/6 displayed)
- 2024LMIC-01. SURVIVAL AND PROGNOSTIC FACTORS IN CHILDHOOD MEDULLOBLASTOMA SINGLE TERTIARY CENTER EXPERIENCE FROM KING FAHAD MEDICAL CITY KFMC SAUDI ARABIA
- 2024Highly synergistic antibacterial activity of copper (II)-based nano metal–organic frameworkcitations
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- 2014Influence of Shot Peening Parameters on Residual Stresses in Flake and Vermicular Cast Ironscitations
- 2012Evaluation of free porosity in shale gas reservoirs (Roseneath and Murteree formations case study)citations
- 2012Mineralogy and Petrophysical Evaluation of Roseneath and Murteree Shale Formations, Cooper Basin, Australia Using QEMSCAN and CT-Scanningcitations
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article
Highly synergistic antibacterial activity of copper (II)-based nano metal–organic framework
Abstract
<p>Copper(II)-based metal–organic framework [Cu<sub>2</sub>(C<sub>6</sub>H<sub>8</sub>O<sub>7</sub>)(H<sub>2</sub>O)<sub>2</sub>]<sub>n</sub>, bulk crystals (Micro-MOF) and nano-MOF particles (Nano-MOF) were synthesized via the hydrothermal method(cit = citric acid(organic linker). The Cu(II) centers of this micro-MOFs, according to a single crystal X-ray study, are surrounded by a 3D structural network and two different coordination environments. The size of micro-MOF was around 200 m, but the width of nano-MOF as-synthesized was close to 120 ± 20 nm. Zone of inhibition and minimal inhibitory concentration (MIC) tests were used to determine the antibacterial effectiveness of the nano-MOF and micro-MOF particle against Escherichia coli and Bacillus subtilis, respectively. While the MIC for micro-MOF is between 200 and 250 ppm and nano-MOF is between 150 and 200 ppm against E. coli and B. subtilis. respectively. The findings show that nano-MOF has more antibacterial power than micro-MOF and ligand by itself. Reactive oxygen species (ROS) and the delayed liberation of incorporating Cu<sup>2+</sup> ions were the foundation for a synergistic antibacterial mechanism that was also put forward.</p>