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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Holler, Mirko
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (17/17 displayed)
- 2024Phase-separated polymer blends for controlled drug delivery by tuning morphologycitations
- 20234D nanoimaging of early age cement hydrationcitations
- 20233D-Imaging of synapses in neuronal tissues with synchrotron X-ray ptychographycitations
- 2023Understanding the microstructure of a core–shell anode catalyst layer for polymer electrolyte water electrolysiscitations
- 2022Near-infrared analysis of nanofibrillated cellulose aerogel manufacturingcitations
- 2022Near-infrared analysis of nanofibrillated cellulose aerogel manufacturingcitations
- 2022Evolution of Hierarchically Porous Nickel Alumina Catalysts Studied by X‐Ray Ptychographycitations
- 20224D Early Age Cement Hydration Analysis by Ptychographic X-ray Computed Tomography and Machine Learning Segmentation
- 2022Alumina-Supported NiMo Hydrotreating CatalystsAspects of 3D Structure, Synthesis, and Activitycitations
- 2021Thermal History of Matrix Forsterite Grains from Murchison Based on High-resolution Tomographycitations
- 2021Quantitative analysis of cementitious materials by X-ray ptychographic nanotomography
- 2021Quantitative analysis of cementitious materials by X-ray ptychographic nanotomography
- 2019Quantitative disentanglement of nanocrystalline phases in cement pastes by synchrotron ptychographic X-ray tomographycitations
- 2019Quantitative disentanglement of nanocrystalline phases in cement pastes by synchrotron ptychographic X-ray tomography
- 2018Small-angle X-ray scattering tensor tomography : Model of the three-dimensional reciprocal-space map, reconstruction algorithm and angular sampling requirementscitations
- 2018Photonic materials for high-temperature applications: synthesis and characterization by X-ray ptychographic tomography
- 2016Internal structure of sponge glass fiber revealed by ptychographic nanotomographycitations
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article
Near-infrared analysis of nanofibrillated cellulose aerogel manufacturing
Abstract
Biomaterial aerogel fabrication by freeze-drying must be further improved to reduce the costs of lengthy freeze-drying cycles and to avoid the formation of spongy cryogels and collapse of the aerogel structures. Residual water content is a critical quality attribute of the freeze-dried product, which can be monitored in-line with near-infrared (NIR) spectroscopy. Predictive models of NIR have not been previously applied for biomaterials and the models were mostly focused on the prediction of only one formulation at a time. We recorded NIR spectra of different nanofibrillated cellulose (NFC) hydrogel formulations during the secondary drying and set up a partial least square regression model to predict their residual water contents. The model can be generalized to measure residual water of formulations with different NFC concentrations and the excipients, and the NFC fiber concentrations and excipients can be separated with the principal component analysis. Our results provide valuable information about the freeze-drying of biomaterials and aerogel fabrication, and how NIR spectroscopy can be utilized in the optimization of residual water content.