| People | Locations | Statistics |
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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Lamprou, Dimitrios A.
Queen's University Belfast
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (22/22 displayed)
- 2023Combining microfluidics and coaxial 3D-bioprinting for the manufacturing of diabetic wound healing dressingscitations
- 2023Combining microfluidics and coaxial 3D-bioprinting for the manufacturing of diabetic wound healing dressingscitations
- 2023Urethane dimethacrylate-based photopolymerizable resins for stereolithography 3D printing: a physicochemical characterisation and biocompatibility evaluationcitations
- 20223D bioprinted scaffolds for diabetic wound healing applicationscitations
- 2022Stereolithography 3D printed implants: a preliminary investigation as potential local drug delivery systems to the earcitations
- 2022High spatial resolution ToF-SIMS imaging and image analysis strategies to monitor and quantify early phase separation in amorphous solid dispersionscitations
- 2022Fused deposition modeling 3D printing proof of concept study for personalised inner ear therapycitations
- 2021Fused deposition modelling for the development of drug loaded cardiovascular prosthesiscitations
- 2021Microfluidics Technology for the Design and Formulation of Nanomedicinescitations
- 2021Optimization of FDM 3D printing process parameters to produce haemodialysis curcumin-loaded vascular graftscitations
- 2021Microfluidics technology for the design and formulation of nanomedicinescitations
- 20203D printing of drug-loaded thermoplastic polyurethane meshes: A potential material for soft tissue reinforcement in vaginal surgerycitations
- 20193D printed microneedle patches using stereolithography (SLA) for intradermal insulin deliverycitations
- 2017Fabrication and characterisation of drug-loaded electrospun polymeric nanofibers for controlled release in hernia repaircitations
- 2017A novel methodology to study polymodal particle size distributions produced during continuous wet granulationcitations
- 2017Probing polydopamine adhesion to protein and polymer films : microscopic and spectroscopic evaluation
- 2017Isatin thiosemicarbazones promote honeycomb structure formation in spin-coated polymer films: concentration effect and release studiescitations
- 2017Probing polydopamine adhesion to protein and polymer films: microscopic and spectroscopic evaluationcitations
- 2016A novel hot-melt extrusion formulation of albendazole for increasing dissolution propertiescitations
- 2016Isatin thiosemicarbazone-blended polymer films for biomedical applications : surface morphology, characterisation and preliminary biological assessmentcitations
- 2014The degradative effects of germicidal light on flexible endoscope material
- 2012Polymer templating of supercooled indomethacin for polymorph selectioncitations
Places of action
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article
Stereolithography 3D printed implants: a preliminary investigation as potential local drug delivery systems to the ear
Abstract
The current study is a preliminary investigation on the use of stereolithography 3D printing technology in the field of personalized medicines and specifically for delivering drugs locally, which can for example usefully be applied to ear infections. The main aim is the development of drug-loaded implants for the treatment of ear diseases, to improve patient compliance and to overcome the limitations of current delivery approaches. Multiple prototypes of implant geometries have been created and printed using a flexible resin containing 0.5% w/v of Levofloxacin. Physicochemical characterization of the printed implants was carried out using a variety of techniques (e.g., microscopic, spectroscopic, and mechanical analysis). Finally, preliminary in vitro tests were performed to evaluate the release profile of Levofloxacin, the prototype implant's stability, and their antimicrobial property. The results obtained show that there is no interaction between the resin and the drug, which is perfectly solubilized in the device. In addition, the results of the mechanical tests show that the material used resists compression without compromising the design itself, and the diffusion test has shown that the drug diffused through the matrix prototype at 50% over 3 weeks. The selected designs showed higher antimicrobial activity on E.coli than on S.aureus.