| People | Locations | Statistics |
|---|---|---|
| Naji, M. |
| |
| Motta, Antonella |
| |
| Aletan, Dirar |
| |
| Mohamed, Tarek |
| |
| Ertürk, Emre |
| |
| Taccardi, Nicola |
| |
| Kononenko, Denys |
| |
| Petrov, R. H. | Madrid |
|
| Alshaaer, Mazen | Brussels |
|
| Bih, L. |
| |
| Casati, R. |
| |
| Muller, Hermance |
| |
| Kočí, Jan | Prague |
|
| Šuljagić, Marija |
| |
| Kalteremidou, Kalliopi-Artemi | Brussels |
|
| Azam, Siraj |
| |
| Ospanova, Alyiya |
| |
| Blanpain, Bart |
| |
| Ali, M. A. |
| |
| Popa, V. |
| |
| Rančić, M. |
| |
| Ollier, Nadège |
| |
| Azevedo, Nuno Monteiro |
| |
| Landes, Michael |
| |
| Rignanese, Gian-Marco |
|
Lamprou, Dimitrios A.
Queen's University Belfast
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (22/22 displayed)
- 2023Combining microfluidics and coaxial 3D-bioprinting for the manufacturing of diabetic wound healing dressingscitations
- 2023Combining microfluidics and coaxial 3D-bioprinting for the manufacturing of diabetic wound healing dressingscitations
- 2023Urethane dimethacrylate-based photopolymerizable resins for stereolithography 3D printing: a physicochemical characterisation and biocompatibility evaluationcitations
- 20223D bioprinted scaffolds for diabetic wound healing applicationscitations
- 2022Stereolithography 3D printed implants: a preliminary investigation as potential local drug delivery systems to the earcitations
- 2022High spatial resolution ToF-SIMS imaging and image analysis strategies to monitor and quantify early phase separation in amorphous solid dispersionscitations
- 2022Fused deposition modeling 3D printing proof of concept study for personalised inner ear therapycitations
- 2021Fused deposition modelling for the development of drug loaded cardiovascular prosthesiscitations
- 2021Microfluidics Technology for the Design and Formulation of Nanomedicinescitations
- 2021Optimization of FDM 3D printing process parameters to produce haemodialysis curcumin-loaded vascular graftscitations
- 2021Microfluidics technology for the design and formulation of nanomedicinescitations
- 20203D printing of drug-loaded thermoplastic polyurethane meshes: A potential material for soft tissue reinforcement in vaginal surgerycitations
- 20193D printed microneedle patches using stereolithography (SLA) for intradermal insulin deliverycitations
- 2017Fabrication and characterisation of drug-loaded electrospun polymeric nanofibers for controlled release in hernia repaircitations
- 2017A novel methodology to study polymodal particle size distributions produced during continuous wet granulationcitations
- 2017Probing polydopamine adhesion to protein and polymer films : microscopic and spectroscopic evaluation
- 2017Isatin thiosemicarbazones promote honeycomb structure formation in spin-coated polymer films: concentration effect and release studiescitations
- 2017Probing polydopamine adhesion to protein and polymer films: microscopic and spectroscopic evaluationcitations
- 2016A novel hot-melt extrusion formulation of albendazole for increasing dissolution propertiescitations
- 2016Isatin thiosemicarbazone-blended polymer films for biomedical applications : surface morphology, characterisation and preliminary biological assessmentcitations
- 2014The degradative effects of germicidal light on flexible endoscope material
- 2012Polymer templating of supercooled indomethacin for polymorph selectioncitations
Places of action
| Organizations | Location | People |
|---|
article
Fused deposition modelling for the development of drug loaded cardiovascular prosthesis
Abstract
Cardiovascular diseases constitute a number of conditions which are the leading cause of death globally. To combat these diseases and improve the quality and duration of life, several cardiac implants have been developed, including stents, vascular grafts and valvular prostheses. The implantation of these vascular prosthesis has associated risks such as infection or blood clot formation. In order to overcome these limitations medicated vascular prosthesis have been previously used. The present paper describes a 3D printing method to develop medicated vascular prosthesis using fused deposition modelling (FDM) technology. For this purpose, rifampicin (RIF) was selected as a model molecule as it can be used to prevent vascular graft prosthesis infection. Thermoplastic polyurethane (TPU) and RIF were combined using hot melt extrusion (HME) to obtain filaments containing RIF concentrations ranging between 0 and 1% (w/w). These materials are capable of providing RIF release for periods ranging between 30 and 80 days. Moreover, TPU-based materials containing RIF were capable of inhibiting the growth of Staphylococcus aureus. This behaviour was observed even for TPU-based materials containing RIF concentrations of 0.1% (w/w). TPU containing 1% (w/w) of RIF showed antimicrobial properties even after 30 days of RIF release. Alternatively, these methods were used to prepare dipyridamole containing TPU filaments. Finally, using a dual extrusion 3D printer vascular grafts containing both drugs were prepared.