| People | Locations | Statistics |
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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Gengenbach, Thomas
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (15/15 displayed)
- 2024Interpretation of Complex X-ray Photoelectron Peak Shapes Part II: Case Study of Fe 2p3/2 fitting applied to Austenitic Stainless Steels 316 and 304.citations
- 2020Covalent sizing surface modification as a route to improved interfacial adhesion in carbon fiber-epoxy compositescitations
- 2020Investigating the real-time dissolution of a compositionally complex alloy using inline ICP and correlation with XPScitations
- 2020Real-time dissolution of a compositionally complex alloy using inline ICP and correlation with XPScitations
- 2020Improving the Stability of Ambient-Processed SnO2-Based, Perovskite Solar Cells by UV-Treatment of the Sub-Cellscitations
- 2020Improving the Stability of Ambient processed, SnO2-Based, Perovskite Solar Cells by the UV-treatment of Sub-Cellscitations
- 2019Electrocatalytic CO2 reduction to formate on Cu based surface alloys with enhanced selectivitycitations
- 2019Fiber with Butterfly Wings: Creating Colored Carbon Fibers with Increased Strength, Adhesion, and Reversible Malleabilitycitations
- 2018Morphology and surface properties of high strength siloxane poly(urethane-urea)s developed for heart valve applicationcitations
- 2017Limitations with solvent exchange methods for synthesis of colloidalfullerenescitations
- 2017Reduction of surface fat formation on spray-dried milk powders through emulsion stabilization with λ-carrageenancitations
- 2016Effect of the deformability of guest particles on the tensile strength of tablets from interactive mixturescitations
- 2014Water-dispersible magnetic carbon nanotubes as T2-weighted MRI contrast agentscitations
- 2012One step multifunctional micropatterning of surfaces using asymmetric glow discharge plasma polymerisation
- 2011Characterization of the surface properties of a model pharmaceutical fine powder modified with a pharmaceutical lubricant to improve flow via a mechanical dry coating approachcitations
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article
Effect of the deformability of guest particles on the tensile strength of tablets from interactive mixtures
Abstract
<p>In this study, we investigated the influence of deformability of specifically-engineered guest particles on the tensile strength of tablets of interactive mixtures. The binder polyvinylpyrrolidone (PVP) of different molecular weights were spray dried with L-leucine to create guest particle formulations. The guest particle formulations were characterized by their particle size, surface L-leucine concentration and glass transition temperature (Tg). These spray-dried particles were then blended with paracetamol to form interactive mixtures, which were compacted into tablets and tablet tensile strength and elastic recovery were determined. The guest particles had particle diameters in the range of 1–10 μm, and surfaces that were L-leucine enriched. The Tg of guest particle formulations increased with increasing molecular weight of the PVP. All the guest particle formulations formed an observed homogeneous interactive mixture with paracetamol. The tensile strength of the tablets of interactive mixtures increased with decreasing Tg of the guest particles. In these interactive mixtures, higher tensile strength was also associated with lower tablet elastic recovery. The elastic recovery of the tablets showed a correlation with the elastic recovery of the tablets of guest particles. Thus, our results indicated that the deformability of guest particles dictates the tensile strength of the tablets of these interactive mixtures.</p>