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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Duarte, Ana Rita C.
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (69/69 displayed)
- 2024Assessment of oxidative stress biomarkers in Palaemon varians exposed to deep eutectic systems
- 2023Using Natural Deep Eutectic Systems as Alternative Media for Ocular Applicationscitations
- 2023Alginate–Chitosan Membranes for the Encapsulation of Lavender Essential Oil and Development of Biomedical Applications Related to Wound Healingcitations
- 2023Menthol-based deep eutectic systems as antimicrobial and anti-inflammatory agents for wound healingcitations
- 2023Hydrophobic DES Based on Menthol and Natural Organic Acids for Use in Antifouling Marine Coatingscitations
- 2023Uncovering biodegradability and biocompatibility of betaine-based deep eutectic systemscitations
- 2023Insights into therapeutic liquid mixtures and formulations towards tuberculosis therapycitations
- 2023Insights into therapeutic liquid mixtures and formulations towards tuberculosis therapycitations
- 2023Is it possible to correlate various physicochemical properties of Natural Deep eutectic systems in order to predict their behaviours as solvents?citations
- 2022Selective terpene based therapeutic deep eutectic systems against colorectal cancercitations
- 2022On the Not So Anomalous Water-induced Structural Transformations of Choline Chloride-Urea (Reline) Deep Eutectic Systemcitations
- 2022Fractionated extraction of polyphenols from mate tea leaves using a combination of hydrophobic/ hydrophilic NADEScitations
- 2022Fractionated extraction of polyphenols from mate tea leaves using a combination of hydrophobic/ hydrophilic NADEScitations
- 2022Assessing the Influence of Betaine-Based Natural Deep Eutectic Systems on Horseradish Peroxidasecitations
- 2022Assessment of deep eutectic solvents toxicity in zebrafish (Danio rerio)citations
- 2022Selective extraction and stabilization of bioactive compounds from rosemary leaves using a biphasic NADEScitations
- 2021Natural deep eutectic systems—A new era of cryopreservationcitations
- 2021Density of deep eutectic solvents ; The path forward cheminformatics-driven reliable predictions for mixturescitations
- 2021Effect of water on the structure and dynamics of choline chloride/glycerol eutectic systemscitations
- 2021Evaluation of Deep Eutectic Systems as an Alternative to Solvents in Painting Conservationcitations
- 2021Deep eutectic systems from betaine and polyols – Physicochemical and toxicological propertiescitations
- 2021Improved storage of influenza HA-VLPs using a trehalose-glycerol natural deep eutectic solvent systemcitations
- 2021Natural deep eutectic systems for nature-inspired cryopreservation of cellscitations
- 2021Unravelling the nature of citric acid:l-arginine:water mixtures ; The bifunctional role of watercitations
- 2021Low-Phytotoxic Deep Eutectic Systems as Alternative Extraction Media for the Recovery of Chitin from Brown Crab Shellscitations
- 2021Low-Phytotoxic Deep Eutectic Systems as Alternative Extraction Media for the Recovery of Chitin from Brown Crab Shellscitations
- 2021Influence of natural deep eutectic systems in water thermal behavior and their applications in cryopreservationcitations
- 2021A look on target-specificity of eutectic systems based on natural bioactive compoundscitations
- 2021Density of deep eutectic solventscitations
- 2020Optimal design of thedes based on perillyl alcohol and ibuprofencitations
- 2020Design and processing of drug delivery formulations of therapeutic deep eutectic systems for tuberculosiscitations
- 2020Collagen from Atlantic cod (Gadus morhua) skins extracted using CO2 acidified water with potential application in healthcarecitations
- 2020Terpene-Based Natural Deep Eutectic Systems as Efficient Solvents to Recover Astaxanthin from Brown Crab Shell Residuescitations
- 2020Advancing spinal fusion: Interbody stabilization by in situ foaming of a chemically modified polycaprolactonecitations
- 2019Unveil the Anticancer Potential of Limomene Based Therapeutic Deep Eutectic Solventscitations
- 2019Therapeutic Role of Deep Eutectic Solvents Based on Menthol and Saturated Fatty Acids on Wound Healingcitations
- 2019Properties of therapeutic deep eutectic solvents of L-arginine and ethambutol for tuberculosis treatmentcitations
- 2019A closer look in the antimicrobial properties of deep eutectic solvents based on fatty acidscitations
- 2018Synthesis and Physical and Thermodynamic Properties of Lactic Acid and Malic Acid-Based Natural Deep Eutectic Solventscitations
- 2018Chitin/Chitosan Based Aerogelscitations
- 2018Subcritical carbon dioxide foaming of polycaprolactone for bone tissue regenerationcitations
- 2018Natural deep eutectic systems as alternative nontoxic cryoprotective agentscitations
- 2018Chitin/chitosan based aerogels: processing and morphologycitations
- 2017Production of Electrospun Fast-Dissolving Drug Delivery Systems with Therapeutic Eutectic Systems Encapsulated in Gelatincitations
- 2017Biomaterials and bioactive agents in spinal fusioncitations
- 2017From honeycomb- to microsphere-patterned surfaces of poly(lactic acid) and a starch-poly(lactic acid) blend via the breath figure methodcitations
- 2017A comparison between pure active pharmaceutical ingredients and therapeutic deep eutectic solventscitations
- 2017Green solvents for enhanced impregnation processes in biomedicinecitations
- 2017Production of electrospun fast-dissolving drug delivery systems with therapeutic eutectic systems encapsulated in gelatincitations
- 2016In vitro bioactivity studies of ceramic structures isolated from marine spongescitations
- 2016Solubility and Permeability Enhancement of active compounds: Therapeutic Deep Eutectic Systems as New Vehicles for Drug Deliverycitations
- 2016Dissolution enhancement of active pharmaceutical ingredients by therapeutic deep eutectic systemscitations
- 2016Preparation of β-glucan scaffolds by hydrogel foaming with supercritical CO2
- 2015Design of controlled release systems for THEDES - Therapeutic deep eutectic solvents, using supercritical fluid technologycitations
- 2015The intersection between chemical and biomedical engineering: green technologies towards the development of enhanced biomaterialscitations
- 2015Ketoprofen-eluting biodegradable ureteral stents by CO2 impregnationcitations
- 2015Design of controlled release systems for THEDES - therapeutic deep eutectic solvents, using supercritical fluid technologycitations
- 2015Coupling Thedes - Therapeutic Deep Eutectic Solvents And Supercritical Fluid Technology for the Development of Controlled Delivery Systemscitations
- 2014Surface modification of silica-based marine sponge bioceramics induce hydroxyapatite formationcitations
- 2014Nanostructured hollow tubes based on chitosan and alginate multilayerscitations
- 2014Bioactive ceramics for tissue engineering and regenerative medicine derived from marine sponges
- 2013Alternative methodology for chitin-hydroxyapatite composites using ionic liquids and supercritical fluid technologycitations
- 2013Alternative methodology for chitin/hydroxyapatite composites using ionic liquids and supercritical fluid technologycitations
- 2013Nanostructured hollow tubes based on chitosan and alginate multilayers
- 2013Marine sponges : a new source of bioactive ceramics for tissue engineering and regenerative medicine applicationscitations
- 2013Unleashing the potential of supercritical fluids for polymer processing in tissue engineering and regenerative medicinecitations
- 2012PDLLA enriched with ulvan particles as a novel 3D porous scaffold targeted for bone engineeringcitations
- 2009Applications of supercritical expansion processes for particle formation
- 2009Processing of novel bioactive polymeric matrixes for tissue engineering using supercritical fluid technologycitations
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article
Design of controlled release systems for THEDES - Therapeutic deep eutectic solvents, using supercritical fluid technology
Abstract
<p>Abstract Deep eutectic solvents (DES) can be formed by bioactive compounds or pharmaceutical ingredients. A therapeutic DES (THEDES) based on ibuprofen, a non-steroidal anti-inflammatory drug (NSAID), and menthol was synthesized and its thermal behavior was analyzed by differential scanning calorimetry (DSC). A controlled drug delivery system was developed by impregnating a starch:poly-Ïμ-caprolactone polymeric blend (SPCL 30:70) with the menthol:ibuprofen THEDES in different ratios (10 and 20 wt%), after supercritical fluid sintering at 20 MPa and 50 °C. The morphological characterization of SPCL matrices impregnated with THEDES was performed by scanning electron microscopy (SEM) and micro-computed tomography (micro-CT). Drug release studies were carried out in a phosphate buffered saline. The results obtained provide important clues for the development of carriers for the sustainable delivery of bioactive compounds.</p>