693.932 PEOPLE
| People | Locations | Statistics |
|---|---|---|
| Naji, M. |
| |
| Motta, Antonella |
| |
| Aletan, Dirar |
| |
| Mohamed, Tarek |
| |
| Ertürk, Emre |
| |
| Taccardi, Nicola |
| |
| Kononenko, Denys |
| |
| Petrov, R. H. | Madrid |
|
| Alshaaer, Mazen | Brussels |
|
| Bih, L. |
| |
| Casati, R. |
| |
| Muller, Hermance |
| |
| Kočí, Jan | Prague |
|
| Šuljagić, Marija |
| |
| Kalteremidou, Kalliopi-Artemi | Brussels |
|
| Azam, Siraj |
| |
| Ospanova, Alyiya |
| |
| Blanpain, Bart |
| |
| Ali, M. A. |
| |
| Popa, V. |
| |
| Rančić, M. |
| |
| Ollier, Nadège |
| |
| Azevedo, Nuno Monteiro |
| |
| Landes, Michael |
| |
| Rignanese, Gian-Marco |
|
Rades, Thomas
University of Copenhagen
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (107/107 displayed)
- 2025Amorphous solid dispersions of amphiphilic polymer excipients and indomethacin prepared by hot melt extrusioncitations
- 2024Amorphous solid dispersions of amphiphilic polymer excipients and indomethacin prepared by hot melt extrusioncitations
- 2024Influence of preparation method and choice of phospholipid on co-amorphization, physical stability, and dissolution behavior of equimolar indomethacin-phospholipid systemscitations
- 2024Molecular interactions of hydrated co-amorphous systems of prilocaine and lidocainecitations
- 2024Anti-plasticizing effect of water on prilocaine and lidocainecitations
- 2024Influence of co-solvents on properties of terpene-based eutectic mixturescitations
- 2024Different or the same? exploring the physicochemical properties and molecular mobility of celecoxib amorphous forms
- 2024Drug–Phospholipid Co-Amorphous Formulations: The Role of Preparation Methods and Phospholipid Selection
- 2023Thermal investigation on hydrated co-amorphous systems of nicotinamide and prilocainecitations
- 2023Considerations on the Kinetic Processes in the Preparation of Ternary Co-Amorphous Systems by Millingcitations
- 2023Stability and intrinsic dissolution of vacuum compression molded amorphous solid dispersions of efavirenzcitations
- 2022Effects of polymer addition on the non-strongly interacting binary co-amorphous system carvedilol-tryptophancitations
- 2022Impact of Molecular Surface Diffusion on the Physical Stability of Co-Amorphous Systemscitations
- 2022A new method to determine drug-polymer solubility through enthalpy of melting and mixing ; ENEngelskEnglishA new method to determine drug-polymer solubility through enthalpy of melting and mixingcitations
- 2022Solventless amorphization and pelletization using a high shear granulator. Part II; Preparation of co-amorphous mixture-layered pellets using indomethacin and argininecitations
- 2022(Co-)amorphization of enantiomers – Investigation of the amorphization process, the physical stability and the dissolution behaviorcitations
- 2022A new method to determine drug-polymer solubility through enthalpy of melting and mixingcitations
- 2022Solventless amorphization and pelletization using a high shear granulator. Part I; feasibility study using indomethacincitations
- 2021The influence of moisture on the storage stability of co-amorphous systemscitations
- 2021Comparison of co-former performance in co-amorphous formulationscitations
- 2020Functionalised calcium carbonate as a coformer to stabilize amorphous drugs by mechanochemical activationcitations
- 2020Hot Melt Coating of Amorphous Carvedilolcitations
- 2020Determination of the Optimal Molar Ratio in Amino Acid-Based Coamorphous Systemscitations
- 2020Direct Measurement of Lateral Molecular Diffusivity on the Surface of Supersaturated Amorphous Solid Dispersions by Atomic Force Microscopycitations
- 2019Process Optimization and Upscaling of Spray-Dried Drug-Amino acid Co-Amorphous Formulationscitations
- 2019Determining Thermal Conductivity of Small Molecule Amorphous Drugs with Modulated Differential Scanning Calorimetry and Vacuum Molding Sample Preparationcitations
- 2019Comparison of bulk and microfluidics methods for the formulation of poly-lactic-co-glycolic acid (PLGA) nanoparticles modified with cell-penetrating peptides of different architecturescitations
- 2019Influence of Glass Forming Ability on the Physical Stability of Supersaturated Amorphous Solid Dispersionscitations
- 2019In situ co-amorphisation in coated tablets – The combination of carvedilol with aspartic acid during immersion in an acidic mediumcitations
- 2019Co-former selection for co-amorphous drug-amino acid formulationscitations
- 2018Influence of PVP molecular weight on the microwave assisted in situ amorphization of indomethacincitations
- 2018The Role of Glass Transition Temperatures in Coamorphous Drug-Amino Acid Formulationscitations
- 2018Glass-Transition Temperature of the β-Relaxation as the Major Predictive Parameter for Recrystallization of Neat Amorphous Drugscitations
- 2018In vitro and in vivo comparison between crystalline and co-amorphous salts of naproxen-argininecitations
- 2018Evaluation of the effects of spray drying parameters for producing cubosome powder precursorscitations
- 2018Evaluation of the effects of spray drying parameters for producing cubosome powder precursorscitations
- 2018Comparison of two DSC-based methods to predict drug-polymer solubilitycitations
- 2018The use of molecular descriptors in the development of co-amorphous formulationscitations
- 2018Glass-Transition Temperature of the β-Relaxation as the Major Predictive Parameter for Recrystallization of Neat Amorphous Drugs.
- 2018The Influence of Polymers on the Supersaturation Potential of Poor and Good Glass Formerscitations
- 2017Hot Melt Extrusion and Spray Drying of Co-amorphous Indomethacin-Arginine With Polymerscitations
- 2017Probing Pharmaceutical Mixtures during Milling:citations
- 2017Amorphization within the tabletcitations
- 2017Influence of preparation pathway on the glass forming abilitycitations
- 2017Microcontainers as an oral delivery system for spray dried cubosomes containing ovalbumincitations
- 2017Performance comparison between crystalline and co-amorphous salts of indomethacin-lysinecitations
- 2016Lipid-Based Formulations Can Enable the Model Poorly Water-Soluble Weakly Basic Drug Cinnarizine to Precipitate in an Amorphous-Salt Form during in Vitro Digestioncitations
- 2016Influence of variation in molar ratio on co-amorphous drug-amino acid systemscitations
- 2016Glass forming ability of amorphous drugs investigated by continuous cooling- and isothermal transformationcitations
- 2016Development of a screening method for co-amorphous formulations of drugs and amino acidscitations
- 2016INFLUENCE OF THE COOLING RATE AND THE BLEND RATIO ON THE PHYSICAL STABILTIY OF CO-AMORPHOUS NAPROXEN/INDOMETHACINcitations
- 2016In Vivo Precipitation of Poorly Soluble Drugs from Lipid-Based Drug Delivery Systemscitations
- 2016Glass solution formation in water - In situ amorphization of naproxen and ibuprofen with Eudragit® E POcitations
- 2016Investigation of physical properties and stability of indomethacin-cimetidine and naproxen-cimetidine co-amorphous systems prepared by quench cooling, coprecipitation and ball millingcitations
- 2016Properties of the Sodium Naproxen-Lactose-Tetrahydrate Co-Crystal upon Processing and Storagecitations
- 2016Supersaturation of zafirlukast in fasted and fed state intestinal media with and without precipitation inhibitorscitations
- 2015Formation mechanism of coamorphous drug−amino acid mixturescitations
- 2015Simple measurements for prediction of drug release from polymer matrices - Solubility parameters and intrinsic viscositycitations
- 2015Predicting Crystallization of Amorphous Drugs with Terahertz Spectroscopy.
- 2015Stabilisation of amorphous furosemide increases the oral drug bioavailability in ratscitations
- 2015Characterization of Amorphous and Co-Amorphous Simvastatin Formulations Prepared by Spray Dryingcitations
- 2015Lysozyme-magnesium aluminum silicate microparticles: Molecular interaction, bioactivity and release studiescitations
- 2015Evaluation of drug-polymer solubility curves through formal statistical analysiscitations
- 2015Solid-state properties and dissolution behaviour of tablets containing co-amorphous indomethacin-argininecitations
- 2015Predicting Crystallization of Amorphous Drugs with Terahertz Spectroscopycitations
- 2014The influence of pressure on the intrinsic dissolution rate of amorphous indomethacincitations
- 2013Nicotine-magnesium aluminum silicate microparticle surface modified with chitosan for mucosal deliverycitations
- 2013Characterization of chitosan-magnesium aluminum silicate nanocomposite films for buccal delivery of nicotinecitations
- 2013Amino acids as co-amorphous stabilizers for poorly water soluble drugs--Part 1citations
- 2013Quantification of the types of water in Eudragit RLPO polymer and the kinetics of water loss using FTIRcitations
- 2013Preparation of an amorphous sodium furosemide salt improves solubility and dissolution rate and leads to a faster Tmax after oral dosing to ratscitations
- 2013Biodegradable microcontainers as an oral drug delivery system for poorly soluble drugs.
- 2013In situ amorphisation of indomethacin with Eudragit® E during dissolutioncitations
- 2013Investigation of the phase separation of PNIPAM using infrared spectroscopy together with multivariate data analysiscitations
- 2012Quantification of process induced disorder in milled samples using different analytical techniques
- 2012The influence of milling on the dissolution performance of simvastatin
- 2012Determination of moisture content in relation to thermal behaviour and plasticization of Eudragit RLPOcitations
- 2012Crystal morphology modification by the addition of tailor-made stereocontrolled poly(N-isopropyl acrylamide)citations
- 2012Atomic pairwise distribution function analysis of the amorphous phase prepared by different manufacturing routescitations
- 2011Assessment of crystalline disorder in cryo-milled samples of indomethacin using atomic pair-wise distribution functionscitations
- 2011Coamorphous drug systems: enhanced physical stability and dissolution rate of indomethacin and naproxencitations
- 2011Novel chitosan-magnesium aluminum silicate nanocomposite film coatings for modified-release tabletscitations
- 2010Physical Changes in Confectionery Products Caused by the Availability of Water, with a Special Focus on Lactitol Crystallizationcitations
- 2010Chitosan-magnesium aluminum silicate nanocomposite filmscitations
- 2010Precipitation of a poorly soluble model drug during in vitro lilpolysiscitations
- 2009Effects of film coating thickness and drug layer uniformity on in vitro drug release from sustained-release coated pelletscitations
- 2009Method of preparation does not affect the miscibility between steroid hormone and polymethacrylatecitations
- 2009Formation kinetics and stability of carbamazepine-nicotinamide cocrystals prepared by mechanical activationcitations
- 2009Quantitative solid-state analysis of three solid forms of ranitidine hydrochloride in ternary mixtures using Raman spectroscopy and X-ray powder diffractioncitations
- 2009Correlating thermodynamic and kinetic parameters with amorphous stabilitycitations
- 2008Miscibility and interactions between 17beta-estradiol and Eudragit RS in solid dispersioncitations
- 2008Chitosan-magnesium aluminum silicate composite dispersionscitations
- 2008Protein delivery using nanoparticles based on microemulsions with different structure-typescitations
- 2007Screening for differences in the amorphous state of indomethacin using multivariate visualizationcitations
- 2007Preparation of glass solutions of three poorly water soluble drugs by spray drying, melt extrusion and ball millingcitations
- 2007Characterisation of colloidal drug delivery systems from the naked eye to Cryo-FESEMcitations
- 2006Preparation of poly (alkylcyanoacrylate) nanoparticles by polymerization of water-free microemulsionscitations
- 2005Using different structure types of microemulsions for the preparation of poly(alkylcyanoacrylate) nanoparticles by interfacial polymerizationcitations
- 2005Quil A-lipid powder formulations releasing ISCOMs and related colloidal structures upon hydrationcitations
- 2005Characterisation of indomethacin and nifedipine using variable-temperature solid-state NMRcitations
- 2004Pseudo-ternary phase diagrams of aqueous mixtures of Quil A, cholesterol and phospholipid prepared by the lipid-film hydration method
- 2004Influence of hydrogenated starch hydrolysates on the glass transition and crystallisation of sugar alcoholscitations
- 2003A new method for the determination of the unfrozen matrix concentration and the maximal freeze-concentrationcitations
- 2002Effects of formulation variables on characteristics of poly (ethylcyanoacrylate) nanocapsules prepared from w/o microemulsionscitations
- 2002Factors affecting incorporation of drug into solid solution with HPMCP during solvent change co-precipitation
- 2001Selection of excipients for melt extrusion with two poorly water-soluble drugs by solubility parameter calculation and thermal analysiscitations
- 2000Stability of polymorphic forms of ranitidine hydrochloride
Places of action
| Organizations | Location | People |
|---|
article
Chitosan-magnesium aluminum silicate composite dispersions
Abstract
Composite dispersions of chitosan (CS), a positively charged polymer, and magnesium aluminum silicate (MAS), a negatively charged clay, were prepared and rheology, flocculate size and zeta potential of the CS-MAS dispersions were investigated. High and low molecular weights of CS (HCS and LCS, respectively) were used in this study. Moreover, the effects of heat treatment at 60 degrees C on the characteristics of the CS-MAS dispersions and the zeta potential of MAS upon addition of CS at different pHs were examined. Incorporation of MAS into CS dispersions caused an increase in viscosity and a shift of CS flow type from Newtonian to pseudoplastic flow with thixotropic properties. Heat treatment brought about a significant decrease in viscosity and hysteresis area of the composite dispersions. Microscopic studies showed that flocculation of MAS occurred after mixing with CS. The size and polydispersity index of the HCS-MAS flocculate were greater than those of the LCS-MAS flocculate. However, a narrower size distribution and the smaller size of the HCS-MAS flocculate were found after heating at 60 degrees C. Zeta potentials of the CS-MAS flocculates were positive and slightly increased with increasing MAS content. In the zeta potential studies, the negative charge of the MAS could be neutralized by the addition of CS. Increasing the pH and molecular weight of CS resulted in higher CS concentrations required to neutralize the charge of MAS. These findings suggest that the electrostatic interaction between CS and MAS caused a change in flow behavior and flocculation of the composite dispersions, depending on the molecular weight of CS. Heat treatment affected the rheological properties and the flocculate size of the composite dispersions. Moreover, pH of medium and molecular weight of CS influence the zeta potential of MAS.