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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Borges, João Paulo Miranda Ribeiro
Universidade Nova de Lisboa
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (32/32 displayed)
- 2024Bioactive Hydroxyapatite Aerogels with Piezoelectric Particlescitations
- 2024Experimental study of Double-Elliptic-Ring-based thermomechanical metamaterials’ behaviourcitations
- 2023Biocomposite Macrospheres Based on Strontium-Bioactive Glass for Application as Bone Fillerscitations
- 2023Thermal, Structural, Morphological and Electrical Characterization of Cerium-Containing 45S5 for Metal Implant Coatingscitations
- 2023Extensive Investigation on the Effect of Niobium Insertion on the Physical and Biological Properties of 45S5 Bioactive Glass for Dental Implantcitations
- 2023Hydroxyapatite-Barium Titanate Biocoatings Using Room Temperature Coblastingcitations
- 2023Bioactive Glass Modified with Zirconium Incorporation for Dental Implant Applicationscitations
- 2022Characterization of a Biocomposite of Electrospun PVDF Membranes with Embedded BaTiO3 Micro- and Nanoparticlescitations
- 2020Conductive electrospun Polyaniline/Polyvinylpyrrolidone nanofibers: Electrical and morphological characterization of new yarns for electronic textilescitations
- 2019Using water to control electrospun Polycaprolactone fibre morphology for soft tissue engineeringcitations
- 2019Electrospun biodegradable chitosan based-poly(urethane urea) scaffolds for soft tissue engineeringcitations
- 2019Extraction of Cellulose Nanocrystals with Structure I and II and Their Applications for Reduction of Graphene Oxide and Nanocomposite Elaborationcitations
- 2019Development of polymeric anepectic meshes: Auxetic metamaterials with negative thermal expansioncitations
- 2019Polymer blending or fiber blending: a comparative study using chitosan and poly(ε-caprolactone) electrospun fiberscitations
- 2018Synthesis, electrospinning and in vitro test of a new biodegradable gelatin-based poly(ester urethane urea) for soft tissue engineeringcitations
- 2017Production of Electrospun Fast-Dissolving Drug Delivery Systems with Therapeutic Eutectic Systems Encapsulated in Gelatincitations
- 2017Tailoring the morphology of hydroxyapatite particles using a simple solvothermal routecitations
- 2017Hybrid polysaccharide-based systems for biomedical applicationscitations
- 2016Thermal and magnetic properties of chitosan-iron oxide nanoparticlescitations
- 2016Natural Nanofibres for Composite Applicationscitations
- 2016A simple sol-gel route to the construction of hydroxyapatite inverted colloidal crystals for bone tissue engineeringcitations
- 2015Osteogenisis enhancement of hydroxyapatite based materials by electrical polarization
- 2015Chitin-Based Nanocomposites: Biomedical Applicationscitations
- 2015Electrospun mats of biodegradable chitosan-based polyurethane urea
- 2015Antimicrobial electrospun silver-, copper-and zinc-doped polyvinylpyrrolidone nanofibers
- 2014Cellulose‐Based Liquid Crystalline Composite Systemscitations
- 2014Effects of surfactants on the magnetic properties of iron oxide colloidscitations
- 2014Electrical polarization of a chitosan-hydroxyapatite composite
- 2013Enhancing the Response of Chemocapacitors with Electrospun Nanofiber Filmscitations
- 2011All-Cellulosic Based Composites
- 2006Mechanical characterization of dense hydroxyapatite blockscitations
- 2001Cellulose-based composite filmscitations
Places of action
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article
Synthesis, electrospinning and in vitro test of a new biodegradable gelatin-based poly(ester urethane urea) for soft tissue engineering
Abstract
<p>Biodegradable polyurethanes have been studied as scaffolds for tissue engineering due to their adjustable physico-chemical properties. In this work, we synthesized a biodegradable gelatin-based poly(urethane urea) using polycaprolactone-diol, as soft segment, and isophorone diisocyanate and gelatin from cold water fish skin as hard segment. The synthesis was confirmed by Fourier transform infrared spectroscopy and proton nuclear magnetic resonance and the influence of the amount of gelatin introduced in the polymer backbone was analyzed by thermal analysis. Gelatin-based poly(urethane urea) electrospun fibrous mats and solvent cast films were then produced and their physico-chemical and biological properties studied. They present an amorphous structure, elastomeric behavior and water contact angles typical of hydrophobic surfaces. Hydrolytic degradation was analyzed in phosphate buffer saline (PBS), lipase and trypsin solutions. No mass changes were detected during 37 days in PBS and trypsin while significant degradation by lipase was observed. Human foetal foreskin fibroblasts were seeded on the fibrous mats and films. Populations were evaluated by colorimetric cell viability assays and morphology by fluorescence imaging. The substrates supported cell adhesion and proliferation. The novel gelatin-based poly(urethane urea) fibrous mats offer attractive physico-chemical and biological properties for soft tissue engineering applications.</p>