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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Nekoueian, Khadijeh
Aalto University
in Cooperation with on an Cooperation-Score of 37%
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Publications (3/3 displayed)
- 2024Advanced nanocellulose-based electrochemical sensor for tetracycline monitoringcitations
- 2023An ultra-sensitive dopamine measurement platform based on molecularly imprinted polymer-carbon hybrid nanomaterials for in vitro usecitations
- 2018Pre-Adsorbed Methylene blue at Carbon-Modified TiO2 Electrode:Application for Lead Sensing in Watercitations
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article
An ultra-sensitive dopamine measurement platform based on molecularly imprinted polymer-carbon hybrid nanomaterials for in vitro use
Abstract
Funding Information: The authors acknowledge D.Sc. Sami Sainio for ta-C/CNFs samples. This work was supported by funding from the European Union's Horizon2020 research project number 68011531 CONNECT. The authors acknowledge the provision of facilities by the Aalto University Ota Nano−Micronova Nanofabrication Center, OtaNano−Nanomicroscopy Center (Aalto-NMC). Funding Information: The authors acknowledge D.Sc. Sami Sainio for ta-C/CNFs samples. This work was supported by funding from the European Union's Horizon2020 research project number 68011531 CONNECT. The authors acknowledge the provision of facilities by the Aalto University Ota Nano−Micronova Nanofabrication Center, OtaNano−Nanomicroscopy Center (Aalto-NMC). Publisher Copyright: © 2023 The Author(s) | openaire: EC/H2020/824070/EU//CONNECT ; In the present study, we designed an ultrasensitive sensing platform for the evaluation of the physiologically relevant values of basal dopamine (DA) in a culture medium as a complex biological environment. The proposed sensing platform was fabricated via the integration of molecular imprinting technology with carbon hybrid nanomaterials. Carbon nanofibers (CNFs) were grown by using plasma-enhanced chemical vapor deposition (PECVD) on tetrahedral amorphous carbon (ta-C) thin films on silicon wafers. The prepared ta-C/CNFs sensing platforms were electrochemically coated with DA-imprinted polypyrrole as the molecularly imprinted polymer (MIP) or "artificial receptors". The three-dimensional MIP receptors were able to determine trace values of DA in phosphate-buffered saline solution (PBS) pH 7.4 (LOD = 5.43 nM) as well as in the absolute culture media such as DMEM/F-12 medium (LOD = 39 nM), DMEM/F-12 medium supplemented with 15% horse serum and 2.5% fetal bovine serum (LOD = 53.26 nM), and F-12 K cell culture medium (LOD = 62.57 nM), with highly physiologically relevant sensitivity and free of interference by other coexisting biomolecules and biological compounds. As all the fabrication steps of the composite electrode ...