| People | Locations | Statistics |
|---|---|---|
| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Linder, Markus B.
Aalto University
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (16/16 displayed)
- 2024Molecular Engineering of a Spider Silk and Mussel Foot Hybrid Protein Gives a Strong and Tough Biomimetic Adhesivecitations
- 2023Pulling and analyzing silk fibers from aqueous solution using a robotic devicecitations
- 2023Pulling and analyzing silk fibers from aqueous solution using a robotic devicecitations
- 2022Recombinant Spider Silk Protein and Delignified Wood Form a Strong Adhesive Systemcitations
- 2022Recombinant Spider Silk Protein and Delignified Wood Form a Strong Adhesive Systemcitations
- 2020Three-Dimensional Printed Cell Culture Model Based on Spherical Colloidal Lignin Particles and Cellulose Nanofibril-Alginate Hydrogelcitations
- 2020Methyl cellulose/cellulose nanocrystal nanocomposite fibers with high ductilitycitations
- 2019Binding Forces of Cellulose Binding Modules on Cellulosic Nanomaterialscitations
- 2018Modification of carbon nanotubes by amphiphilic glycosylated proteinscitations
- 2018Self-Coacervation of a Silk-Like Protein and Its Use As an Adhesive for Cellulosic Materialscitations
- 2015Modular Architecture of Protein Binding Units for Designing Properties of Cellulose Nanomaterialscitations
- 2015Enhanced plastic deformations of nanofibrillated cellulose film by adsorbed moisture and protein-mediated interactionscitations
- 2014Structural characterization and tribological evaluation of quince seed mucilagecitations
- 2013The role of hemicellulose in nanofibrillated cellulose networkscitations
- 2013Drug release from nanoparticles embedded in four different nanofibrillar cellulose aerogelscitations
- 2012Adhesion and tribological properties of hydrophobin proteins in aqueous lubrication on stainless steel surfacescitations
Places of action
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article
Drug release from nanoparticles embedded in four different nanofibrillar cellulose aerogels
Abstract
Highly porous nanocellulose aerogels prepared by freeze-drying from various nanofibrillar cellulose (NFC) hydrogels are introduced as nanoparticle reservoirs for oral drug delivery systems. Here we show that beclomethasone dipropionate (BDP) nanoparticles coated with amphiphilic hydrophobin proteins can be well integrated into the NFC aerogels. NFCs from four different origins are introduced and compared to microcrystalline cellulose (MCC). The nanocellulose aerogel scaffolds made from red pepper (RC) and MCC release the drug immediately, while bacterial cellulose (BC), quince seed (QC) and TEMPO-oxidized birch cellulose-based (TC) aerogels show sustained drug release. Since the release of the drug is controlled by the structure and interactions between the nanoparticles and the cellulose matrix, modulation of the matrix formers enable a control of the drug release rate. These nanocomposite structures can be very useful in many pharmaceutical nanoparticle applications and open up new possibilities as carriers for controlled drug delivery.