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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Banquy, Xavier
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (5/5 displayed)
- 2024Bioinspired Bottlebrush Polymers Effectively Alleviate Frictional Damage Both in Vitro and in Vivocitations
- 2024Layer‐by‐Layer Deposition of a Polycationic Bottlebrush Polymer with Hyaluronic Acid Reveals Unusual Assembly Mechanism and Selective Effect on Cell Adhesion and Fatecitations
- 2023New trends for osteoarthritis: Biomaterials, models and modelingcitations
- 2023Bottlebrush polymer with dual functionality for osteoarthritis treatment: curcumin delivery and lubrication propertiescitations
- 2018Lubrication and Wear Protection of Micro-Structured Hydrogels Using Bioinspired Fluidscitations
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article
New trends for osteoarthritis: Biomaterials, models and modeling
Abstract
The burden of osteoarthritis (OA), one of the major causes of functional disabilities in humans and animals, continues to increase worldwide while no disease-modifying OA drugs (DMOADs) that either slow down or reverse disease progression have been made available. Here, we provide a brief overview of recent advances in: designing new OA drug delivery approaches, focusing on lubrication-based biomaterials and drug delivery systems, such as hydrogels, liposomes, dendrimers, micro- and nanoparticles; using either large (horse) or small (zebrafish) relevant animal models to evaluate new therapeutic strategies; and OA in vitro modeling, focusing on 3D (organoid) models of cartilage regarding the Replace, Reduce and Refine (3R) principle of animal experimentation.