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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Mohammed, Afzal-Ur-Rahman
Aston University
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (6/6 displayed)
- 2016Characterisation and surface-profiling techniques for composite particles produced by dry powder coating in pharmaceutical drug deliverycitations
- 2015Functionalised particles using dry powder coating in pharmaceutical drug deliverycitations
- 2011Physicochemical characterisation, drug polymer dissolution and in vitro evaluation of phenacetin and phenylbutazone solid dispersions with polyethylene glycol 8000citations
- 2011Systems biology approach to study permeability of paracetamol and its solid dispersioncitations
- 2011Effects of ball-milling on PLGA polymer and its implication on lansoprazole-loaded nanoparticles
- 2011The influence of formulation and manufacturing process parameters on the characteristics of lyophilized orally disintegrating tabletscitations
Places of action
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article
Characterisation and surface-profiling techniques for composite particles produced by dry powder coating in pharmaceutical drug delivery
Abstract
<p>The production of composite particles using dry powder coating is a one-step, environmentally friendly, process for the fabrication of particles with targeted properties and favourable functionalities. Diverse functionalities, such flowability enhancement, content uniformity, and dissolution, can be developed from dry particle coating. In this review, we discuss the particle functionalities that can be tailored and the selection of characterisation techniques relevant to understanding their molecular basis. We address key features in the powder blend sampling process and explore the relevant characterisation techniques, focussing on the functionality delivered by dry coating and on surface profiling that explores the dynamics and surface characteristics of the composite blends. Dry particle coating is a solvent- and heat-free process that can be used to develop functionalised particles. However, assessment of the resultant functionality requires careful selection of sensitive analytical techniques that can distinguish particle surface changes within nano and/or micrometre ranges.</p>