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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Singh, M.
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (14/14 displayed)
- 2023High Temperature Compressive Strength and Creep Behavior of Si-Ti-C-O Fiber-Bonded Ceramicscitations
- 2022Piezoelectric Materials based Phototronics
- 2022Studies on the role of ion mass and energy in the defect production in irradiation experiments in tungstencitations
- 2021Fixation of transparent bone pins with photocuring biocompositescitations
- 2021Nanoscale control of oxides by laser ablation: design and applications
- 2015Sliding wear resistance of sintered SiC-fiber bonded ceramicscitations
- 2015Characterization of metal free D- (-A)2 organic dye and its application as co-sensitizer along with N719 dye for efficient dye sensitized solar cellscitations
- 2013Vapor phase approach for iron oxide nanoparticle synthesis from solid precursorscitations
- 2010ALUMINUM NITRIDE MULTI-WALLED NANOTUBE (MWNTs) NANOCOMPOSITE BY DIRECT IN-SITU GROWTH OF CNTs ON ALUMINUM NITRIDE PARTICLEScitations
- 2009MODELING OF FIELD ASSISTED SINTERING TECHNOLOGY (FAST) AND ITS APPLICATION TO ELECTRO-CONDUCTIVE SYSTEMScitations
- 2008Ferromagnetism and magnetodielectric effect in insulating LaBiMn4∕3Co2∕3O6 thin filmscitations
- 2008THE EFFECT OF THE ELECTRICAL PROPERTIES ON THE PULSED ELECTRIC CURRENT SINTERING BEHAVIOR OF ZrO(2) BASED CERAMIC COMPOSITES
- 2006Association of APOE (Hha1) and ACE (I/D) gene polymorphisms with type 2 diabetes mellitus in North West India.citations
- 2002Hard and tough ZrO2-WC composites from nanosized powders
Places of action
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article
Association of APOE (Hha1) and ACE (I/D) gene polymorphisms with type 2 diabetes mellitus in North West India.
Abstract
Familial and epidemiological studies have shown that genetic factors play a role in the development and progression of type 2 diabetes mellitus (T2DM). Asian Indians have shown an increasing prevalence of T2DM. Apolipoprotein E (APOE) and Angiotensin-1 converting enzyme (ACE) I/D polymorphisms have been associated with T2DM. This study examined the association of APOE and ACE genes with T2DM patients of Punjab, India. APOE (HhaI) and ACE (I/D) genotypes analysed by polymerase chain reaction were available from 90 patients and 97 random healthy controls. All loci and populations are in Hardy-Weinberg equilibrium. There is no significant association of APOE vis-à-vis T2DM, however APOE*4 allele frequency is low in diabetics (3.9% and 8.8%). DD genotype and *D allele of ACE are associated with T2DM (OR=1.90, p<0.05, and OR=1.58, p<0.05, respectively). Recessive and multiplicative mode of inheritance for *D allele provided the strongest support for the association. Height, weight and BMI did not reveal any significant association with APO or ACE. DD-33 and ID-23 combinations (ACE-APOE) showed higher odds of 2.01 and 2.14, respectively. ACE but not APOE polymorphism is positively associated with T2DM in Indian population, however, the synergistic effects of DD-33 and ID-23 are also evident.