| People | Locations | Statistics |
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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Fawzy, Amr
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (23/23 displayed)
- 2024Effect of inositol hexaphosphate acid versus polyacrylic acid on dentin properties and adhesion of a self-adhesive restorative material to dentincitations
- 2024The Synergistic Effect of High Intensity Focused Ultrasound on In-vitro Remineralization of Tooth Enamel by Calcium Phosphate Ion Clusterscitations
- 2024Flowable resin-based composites modified with chlorhexidine-loaded mesoporous silica nanoparticles induce superior antibiofilm properties
- 2022Cytotoxicity and antimicrobial efficiency of ZrO2 nanoparticles reinforced 3D printed resinscitations
- 2022Development of 3D printed dental resin nanocomposite with graphene nanoplatelets enhanced mechanical properties and induced drug-free antimicrobial activity.citations
- 2021Development of 3D printed resin reinforced with modified ZrO2 nanoparticles for long-term provisional dental restorationscitations
- 2021Formulation of pH-sensitive chlorhexidine-loaded/mesoporous silica nanoparticles modified experimental dentin adhesivecitations
- 2020The Effect of Cross-linking Efficiency of Drug-Loaded Novel Freeze Gelated Chitosan Templates for Periodontal Tissue Regenerationcitations
- 2020Effect of acid etching on dentin bond strength of ultra-mild self-etch adhesivescitations
- 2020Properties of a modified quaternary ammonium silane formulation as a potential root canal irrigant in endodonticscitations
- 2020In vitro bonding performance of modern self-adhesive resin cements and conventional resin-modified glass ionomer cements to prosthetic substratescitations
- 2019Resin-based dental composites for tooth filling
- 2019Macrophage response and surface analysis of dental cementum after treatment with high intensity focused ultrasoundcitations
- 2019An in vitro study of a novel quaternary ammonium silane endodontic irrigantcitations
- 2019Co-blend application mode of bulk fill composite resincitations
- 2018In vitro assessment of ribose modified two-step etch-and-rinse dentine adhesivecitations
- 2017Proanthocyanidins-Loaded Nanoparticles Enhance Dentin Degradation Resistancecitations
- 2017Potentiating the antibacterial effect of silver nanospheres by surface-capping with chlorhexidine gluconatecitations
- 2015Characterization of antibacterial and adhesion properties of chitosan-modified glass ionomer cementcitations
- 2012Riboflavin as a dentin crosslinking agentcitations
- 2009Effect acidic and alkaline/heat treatments on the bond strength of different luting cements to commercially pure titaniumcitations
- 2009Tensile bond strength of immediately repaired anterior microfine hybrid restorative composite using nontrimmed hourglass specimens
- 2008Effect of surface treatments on the tensile bond strength of repaired water-aged anterior restorative micro-fine hybrid resin compositecitations
Places of action
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article
Properties of a modified quaternary ammonium silane formulation as a potential root canal irrigant in endodontics
Abstract
<p>Objectives: Evaluate a new modified quaternary ammonium silane irrigant solution for its antimicrobial, cytotoxic and mechanical properties of dentine substrate. Methods: Root canal preparation was performed using stainless steel K-files™ and F4 size protaper with irrigation protocols of 6% NaOCl + 2% CHX; 3.5% QIS; 2% QIS and sterile saline. Biofilms were prepared using E. faecalis adjusted and allowed to grow for 3 days, treated with irrigants, and allowed to grow for 7 days. AFM was performed and surface free energy calculated. MC3T3 cells were infected with endo irrigant treated E. faecalis biofilms. Raman spectroscopy of biofilms were performed after bacterial re-growth on root dentine and exposed to different irrigation protocols and collagen fibers analysed collagen fibers using TEM. Antimicrobial potency against E. faecalis biofilms and cytoxicity against 3T3 NIH cells were also. Resin penetration and MitoTracker green were also evaluated for sealer penetration and mitochondrial viability. Data were analysed using One-way ANOVA, principal component analysis and post-hoc Fisher's least-significant difference. Results: Elastic moduli were maintained amongst control (5.5 ± 0.9) and 3.5% QIS (4.4 ± 1.1) specimens with surface free energy higher in QIS specimens. MC3T3 cells showed reduced viability in 6%NaOCl+2%CHX specimens compared to QIS specimens. DNA/purine were expressed in increased intensities in control and 6% NaOCl + 2% CHX specimens with bands around 480−490 cm<sup>−1</sup> reduced in QIS specimens. 3.5% QIS specimens showed intact collagen fibrillar network and predominantly dead bacterial cells in confocal microscopy. 3.5% QIS irrigant formed a thin crust-type surface layer with cytoplasmic extensions of 3T3NIH spread over root dentine. Experiments confirmed MitoTracker accumulation in 3.5% treated cells. Significance: Novel QIS root canal irrigant achieved optimum antimicrobial protection inside the root canals facilitating a toxic effect against the Enterococcus faecalis biofilm. Root dentine substrates exhibited optimum mechanical properties and there was viability of fibroblastic mitochondria.</p>