| People | Locations | Statistics |
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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Deb, Sanjukta
King's College London
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (16/16 displayed)
- 2021Antimicrobials in Dentistrycitations
- 2020Ex vivo investigations on bioinspired electrospun membranes as potential biomaterials for bone regeneration.citations
- 2020An in vitro assessment of the physical properties of manually- mixed and encapsulated glass-ionomer cementscitations
- 2020Evaluation of the effects of polishing systems on surface roughness and morphology of dental composite resincitations
- 2018Combinatorial design of calcium meta phosphate poly(vinyl alcohol) bone-like biocompositescitations
- 2017Evaluation of dental adhesive systems incorporating an antibacterial monomer eugenyl methacrylate (EgMA) for endodontic restorationscitations
- 2017Synthesis of irregular graphene oxide tubes using green chemistry and their potential use as reinforcement materials for biomedical applicationscitations
- 2016Influence of a polymerizable eugenol derivative on the antibacterial activity and wettability of a resin composite for intracanal post cementation and core build-up restorationcitations
- 2014Fabrication and characterization of polymer composites for endodontic usecitations
- 2013Preparation of multicompartment sub-micron particles using a triple-needle electrohydrodynamic devicecitations
- 2012Synthesis and Preliminary Evaluation of a Polyolefin-based Core for Carrier-based Root Canal Obturationcitations
- 2011Porosity, Micro-Hardness and Morphology of White and Gray Portland Cements in Relation to Their Potential in the Development of New Dental Filling Materialscitations
- 2011Porosity, Micro-Hardness and Morphology of White and Gray Portland Cements in Relation to Their Potential in the Development of New Dental Filling Materialscitations
- 2006From natural products to polymeric derivatives of "Eugenol":A new approach for preparation of dental composites and orthopedic bone cementscitations
- 2006From natural products to polymeric derivatives of “Eugenol”: a new approach for preparation of dental composites and orthopedic bone cementscitations
- 2002Characterization of new acrylic bone cements prepared with oleic acid derivativescitations
Places of action
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article
Influence of a polymerizable eugenol derivative on the antibacterial activity and wettability of a resin composite for intracanal post cementation and core build-up restoration
Abstract
Objectives Eugenol has been used in dentistry due to its ability to inhibit the growth of a range of microorganisms, including facultative anaerobes commonly isolated from infected root canals. The aim of this study was to evaluate the antibacterial activity of the experimental composites containing eugenyl methacrylate monomer (EgMA), a polymeric derivative of eugenol, against a range of oral bacteria, commonly associated with failure of coronal and endodontic restorations. In vitro composite behavior and wettability were also studied in conjunction with their antibacterial activity. Methods EgMA monomer (5 and 10% by weight) was added into BisGMA/TEGDMA resin based formulations with filler mixtures of hydroxyapatite (HA) and zirconium oxide ZrO2. The antibacterial activity of the experimental composites against Enterococcus faecalis, Streptococcus mutans and Propionibacterium acnes were evaluated by direct contact test and compared with composite formulation without inclusion of EgMA. To clarify the antibacterial mode of action, agar diffusion test (ADT) was also performed. Water sorption, solubility, diffusion coefficient, contact angle and surface free energy as complementary clinically relevant properties were determined. Results Water sorption and wettability studies showed reduction of water uptake and surface free energy values with increasing content of EgMA monomer, resulting in significant increase in the hydrophobicity of the composites. No inhibition zones were detected in any of the composites tested against the three bacteria employed as expected, due to the absence of any leachable antibacterial agent. The covalently anchored EgMA monomer with the composite surface exhibited an effective bacteriostatic activity by reducing the number of CFUs of the three species of bacteria tested with no significant dependence on the concentration of EgMA at 5 and 10% by weight. The surface antibacterial activity R of the experimental composites were different against the three tested species with values in the range 2.7–6.1 following the order E. faecalis < S. mutans < P. acnes. Significance The incorporation of EgMA monomer within polymerizable formulations provides a novel approach to yield intrinsically antibacterial resin composites for different dental applications.