| People | Locations | Statistics |
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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Peplińska, Barbara
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (14/14 displayed)
- 2021Nanocellulose Production Using Ionic Liquids with Enzymatic Pretreatmentcitations
- 2020Nanocomposite Gel as Injectable Therapeutic Scaffold: Microstructural Aspects and Bioactive Propertiescitations
- 2019Fluorescein ether-ester dyes for labeling of fluorinated methacrylate nanoparticlescitations
- 2018Silver and ultrasmall iron oxides nanoparticles in hydrocolloids: Effect of magnetic field and temperature on self-organizationcitations
- 2018Nano-multilayered coatings of (TiAlSiY)N/MeN (Me=Mo, Cr and Zr): Influence of composition of the alternating layer on their structural and mechanical propertiescitations
- 2018Gel with silver and ultrasmall iron oxide nanoparticles produced with Amanita muscaria extract: physicochemical characterization, microstructure analysis and anticancer propertiescitations
- 2018ZnS coating for enhanced environmental stability and improved properties of ZnO thin filmscitations
- 2017Self-organizing silver and ultrasmall iron oxide nanoparticles prepared with ginger rhizome extract: Characterization, biomedical potential and microstructure analysis of hydrocolloidscitations
- 2017Release and cytotoxicity studies of magnetite/Ag/antibiotic nanoparticles: An interdependent relationshipcitations
- 2016Gradient nanostructured coatings obtained by magnetron sputtering of a multiphase AlN–TiB<inf>2</inf>–TiSi<inf>2</inf> targetcitations
- 2016Fourier transform infrared and Raman spectroscopy studies on magnetite/Ag/antibiotic nanocompositescitations
- 2016High temperature behavior of functional TiAlBSiN nanocomposite coatingscitations
- 2015Synthesis and characterization of magnetite/silver/antibiotic nanocomposites for targeted antimicrobial therapycitations
- 2015Atomic layer deposition TiO2 coated porous silicon surface: Structural characterization and morphological featurescitations
Places of action
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article
Release and cytotoxicity studies of magnetite/Ag/antibiotic nanoparticles: An interdependent relationship
Abstract
<p>Though the cytotoxic properties of magnetite nanoparticles (NPs) are rather well investigated and known to be dose dependent and rather low, surface functionalization can drastically change their properties. To determine whether the cytotoxicity of magnetite/Ag/antibiotic NPs may be associated, among other things, with iron, silver and antibiotic release, this study investigates the release profiles and cytotoxicity of magnetite/Ag/rifampicin and magnetite/Ag/doxycycline NPs compares it similar profiles from magnetite, magnetite/Ag NPs and antibiotics. It was established that the studied NPs released not only water-soluble substances, such as antibiotics, but also poorly-soluble ones, such as iron and silver. The deposition of silver on the magnetite surface promotes the release of iron by the formation of a galvanic couple. Antibiotic adsorbed on the magnetite/Ag surface plays a dual role in the galvanic corrosion processes: as a corrosion inhibitor for iron oxides and as a corrosion promoter for silver. Magnetite/Ag/rifampicin and magnetite/Ag/doxycycline. NPs were found to have greater cytotoxicity towards the HEK293T cell line than magnetite NPs. These results were attributed to the combined toxic action of the released iron, silver ions and antibiotics. Intensive and simultaneous release of the NP components caused cell stress and suppressed their growth.</p>