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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Cavallotti, C.
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Publications (5/5 displayed)
- 2008Emollients, moisturizers, and keratolytic agents in psoriasis.citations
- 2008NorDATA: an Original Ligand Based on the Norbornane Skeleton. Synthesis and Metal Complexes Thermodynamic Characterizationcitations
- 2008An unusual gadolinium ten-coordinated dimeric complex in the series of MRI contrast agents: Na[Gd(H2O)AAZTA]∙3H2Ocitations
- 2008An unusual gadolinium ten-coordinated dimeric complex in the series of MRI contrast agents: Na[Gd(H2O) AAZTA] center dot 3H(2)Ocitations
- 2008An unusual gadolinium ten-coordinated dimeric complex in the series of MRI contrast agents : Na[Gd(H2O)AAZTA] • 3H2Ocitations
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article
Emollients, moisturizers, and keratolytic agents in psoriasis.
Abstract
Emollients, moisturizers, and keratolytic agents are essential in the topical treatment of psoriasis. They are adjuvants for classic treatments and help to reduce the scale load of individual patients. The major role for emollients and moisturizers is the supportive role in normalizing hyperproliferation, differentiation, and apoptosis; furthermore, they exert anti-inflammatory effects, for example, through physiologic lipids. Subsequently, an improved barrier function and stratum corneum hydration makes the epidermis more resistant to external stressors and reduces the induction of Koebner phenomena. Most of the emollients are lipid-rich (sometimes oily). The keratolytic agents, especially salicylic acid, and higher concentration of urea should be used in the initial keratolytic phase, whereas moisturizing products and emollients are especially suitable in the intermediate phase and the chronic/remission phase of psoriasis. They should be combined with bath oils.