| People | Locations | Statistics |
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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Gernaey, Krist V.
Technical University of Denmark
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (12/12 displayed)
- 2024Production of phosphate biofertilizers as a booster for the techno-economic and environmental performance of a first-generation sugarcane ethanol and sugar biorefinerycitations
- 2023The effects of low oxidation-reduction potential on the performance of full-scale hybrid membrane-aerated biofilm reactorscitations
- 2022Economic and environmental analysis of bio-succinic acid production: from established processes to a new continuous fermentation approach with in-situ electrolytic extractioncitations
- 2019A Simulation-Based Superstructure Optimization Approach for Process Synthesis and Design Under Uncertainty
- 2018Mechanistic modeling of cyclic voltammetry: A helpful tool for understanding biosensor principles and supporting design optimizationcitations
- 2018Rapid and Efficient Development of Downstream Bio-Pharmaceutical Processing Alternatives
- 2014The Electrical Breakdown of Thin Dielectric Elastomerscitations
- 2013Applying mechanistic models in bioprocess development.citations
- 2013Applying mechanistic models in bioprocess development.citations
- 2012Evaluation of the energy efficiency of enzyme fermentation by mechanistic modelingcitations
- 2010Embedded resistance wire as a heating element for temperature control in microbioreactorscitations
- 2008Multivariate models for prediction of rheological characteristics of filamentous fermentation broth from the size distributioncitations
Places of action
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article
Economic and environmental analysis of bio-succinic acid production: from established processes to a new continuous fermentation approach with in-situ electrolytic extraction
Abstract
Many recent attempts to commercialize bio-succinic acid (bio-SA) endedto be unsuccessful after a start flourishing moment. Furthermore, theimproved environmental performance of bio-SA production processescompared to petroleum-based SA is still uncertain. In this study atechno-economic analysis was conducted comparing four bio-SAmanufacturing processes in terms of net present value and minimumselling price. Two of the simulated processes are based on patentsreleased by bio-SA manufacturing companies (I) Roquette/DSM (Reverdia)and (II) DNP Green Technology /ARD (BioAmber). A third process is basedon a Michigan State University patent (III) and a fourth process isconceptual (IV). The conceptual process IV was demonstrated to have <50% lower capital costs and ∼40 to 55% lower manufacturing costs thanthe other processes. With a minimum selling price of 1.4 USD kg<sup>-1</sup>, process IV would be cheaper than petroleum based succinic acid (∼2.0 USD kg<sup>-1</sup>).The Reverdia-based process can also be competitive, while process IIIand particularly the BioAmber-based process II are not profitable.Ion-exchange columns, nanofiltration and anion exchange membranes areshown to be key technologies for lowering bio-SA manufacturing costs.Continuous bio-SA fermentation with <em>in situ</em>-like extraction canchange the bio-SA market, but the environmental sustainabilityassessment reveals only marginal differences compared withpetroleum-based SA. Low pH “aerobic fermentation” is likely to be a moresustainable strategy compared to neutral pH “aerobic fermentation”.