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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Lazzeri, Andrea
University of Pisa
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (58/58 displayed)
- 2024ON THE EFFECTS OF THE INTERPHASE ON THE DAMPING OF CFRP STRUCTURES: AN EXPERIMENTAL INVESTIGATION
- 2024Toughened Vinyl Ester Resin Reinforced with Natural Flax Fabrics
- 2023Chitin nanofibrils modulate mechanical response in tympanic membrane replacementscitations
- 2023Investigation of Novel Flax Fiber/Epoxy Composites with Increased Biobased Contentcitations
- 2023Investigation of Novel Flax Fiber/Epoxy Composites with Increased Biobased Contentcitations
- 2023A Straightforward Method to Produce Multi-Nanodrug Delivery Systems for Transdermal/Tympanic Patches Using Electrospinning and Electrospraycitations
- 2022Micromechanical Deformation Processes and Failure of PBS Based Composites Containing Ultra-Short Cellulosic Fibers for Injection Molding Applicationscitations
- 2022Size effect of carbon fiber-reinforced silicon carbide composites (C/C-SiC) : Part 2 - tensile testing with alignment devicecitations
- 2022Essential Work of Fracture and Evaluation of the Interfacial Adhesion of Plasticized PLA/PBSA Blends with the Addition of Wheat Bran By-Productcitations
- 2022Formulazioni polimeriche di colle a caldo di origine naturale per applicazioni come rivestimenti contenenti biomolecole attive
- 2021Polylactic Acid and Poly(Butylene Adipate-Co-Terephthalate) Blends Plasticised with Lactic Oligomers and Epoxy Reactive Plasticizers
- 2021New insights in bioplastics processing and recycling
- 2020Overview of Agro-Food Waste and by Products Valorization for Polymer Synthesis, and Modification for Bio-Composite Production.
- 2020Bio-Based Packaging: Materials, Modifications, Industrial Applications and Sustainabilitycitations
- 2020Electric field induced alignment of graphene oxide nanoplatelets in polyethersulfone matrixcitations
- 2019Thermal and Mechanical Properties of Biocomposites Made of Poly(3-hydroxybutyrate-co-3-hydroxyvalerate) and Potato Pulp Powdercitations
- 2019Processability and degradability of PHA-based composites in terrestrial environmentscitations
- 2019Raw protein hydrolysates from tanning industry in blends with Polybutylene succinate adipate (PBSA) for agricultural applications
- 2019Thermal, Mechanical, and Rheological Properties of Biocomposites Made of Poly(lactic acid) and Potato Pulp Powdercitations
- 2019Rigid filler toughening in PLA-Calcium Carbonate composites: Effect of particle surface treatment and matrix plasticizationcitations
- 2019Chitin Nanofibrils in Poly(Lactic Acid) (PLA) Nanocomposites: Dispersion and Thermo-Mechanical Propertiescitations
- 2019Improved impact properties in poly(lactic acid) (PLA) blends containing cellulose acetate (CA) prepared by reactive extrusioncitations
- 2018Poly(lactic acid) (PLA) Based Tear Resistant and Biodegradable Flexible Films by Blown Film Extrusioncitations
- 2018Biopolyesters and bio based additives based blends and composites for application in packaging and agriculture
- 2018Effect of different nucleating agent on crystallinity and properties of polylactic acidcitations
- 2018Nano-calcite preparation aimed at consolidating stones for cultural heritage applicationscitations
- 2017Effect of nucleating agents on crystallinity and properties of poly (lactic acid) (PLA)citations
- 2017Effects of waviness on fiber-length distribution and interfacial shear strength of natural fibers reinforced compositescitations
- 2017New Bio-Composites Based on Polyhydroxyalkanoates and Posidonia oceanica Fibres for Applications in a Marine Environmentcitations
- 2017Reactively extruded ecocomposites based on poly(lactic acid)/bisphenol A polycarbonate blends reinforced with regenerated cellulose microfiberscitations
- 2016Processing routes for the preparation of poly(lactic acid)/cellulose-nanowhisker nanocomposites for packaging applications
- 2016Reactive extrusion of PLA/PC blends and composites
- 2016New Polymer Architectures for Architectural Stone Preservation
- 2016Composition dependence of the synergistic effect of nucleating agent and plasticizer in poly(lactic acid): a Mixture Design studycitations
- 2016Recent Advances in Biotechnology, Vol. 2citations
- 2016Thermal Properties of Plasticized Poly (Lactic Acid)(PLA) Containing Nucleating Agentcitations
- 2015EMPLOYMENT OF HIGH-FREQUENCY ELECTRO-MAGNETIC TECHNOLOGIES FOR COMPETITIVE PROCESSING OF CERAMIC MATRIX COMPOSITES AND GRAPHITE EXPANSION
- 2015Flexible polyurethane foams green production employing lignin or oxypropylated lignincitations
- 2015NATURAL NANO OR MICRO POLYSACCHARIDE FIBERS IN BIOPOLYESTERS MATRICES
- 2015Comparison of precipitated calcium carbonate/polylactic acid and halloysite/polylactic acid nanocompositescitations
- 2015Development of Fibres-Reinforced Biodegradable Composites
- 2014Modification of the mechanical behavior in the glass transition region of poly(lactic acid) (PLA) through catalyzed reactive extrusion with poly(carbonate) (PC)citations
- 2014EFFECT OF AGING TIME ON MECHANICAL PROPERTIES OF PLASTICIZED POLY(HYDROXYBUTYRATE) (PHB)citations
- 2014Dependence of the Pukánszky's interaction parameter B on the interface shear strength (IFSS) of nanofiller- and short fiber-reinforced polymer compositescitations
- 2013Green synthesis of flexible polyurethane foams from liquefied lignincitations
- 2012Properties of whey-protein-coated films and laminates as novel recyclable food packaging materials with excellent barrier propertiescitations
- 2012"Green" biocomposites based on cellulose diacetate and regenerated cellulose microfibers: Effect of plasticizer content on morphology and mechanical propertiescitations
- 2011Der Einfluss einer Oberflächenbeschichtung von gefälltem Calciumcarbonat auf die mechanischen Eigenschaften von polymeren Nanocomposites
- 2009Synthesis of Bioactive Hydroxyapatite-Zirconia Toughened Composites for Bone Replacementcitations
- 2008Synthesis of Bioactive Hydroxyapatite-Zirconia Toughened Composites for Bone Replacementcitations
- 2008Modeling and development of a microwave heated pilot plant for the production of SiC-based ceramic matrix composites
- 2007Effect of both uncoated and coated calcium carbonate on fracture toughness of HDPE/CaCO3 nanocompositescitations
- 2005Filler Toughening of Plastics. Part 1 - The Effect of Surface Interactions on Physico-Mechanical Properties and Rheological Behaviour of Ultrafine CaCO3/High Density Polyethylene Nanocompositescitations
- 2004Volume Strain Measurements on CaCO3/Polypropylene Particulate Composites: the Effect of Particle Sizecitations
- 2002The Role of the Interface on the Deformation Mechanism of Glass Fibers/Polypropylene Compositescitations
- 2001A Micromechanical Model for Multiple Crazing in High Impact Polystirenecitations
- 2000Colour Development during Devitrification in Li2O-ZnO-Al2O3-SiO2 Glasses under Conventional and Microwave Heating
- 2000Recent Developments in the Modeling of Dilatational Yielding in Toughened Plastics
Places of action
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article
Chitin nanofibrils modulate mechanical response in tympanic membrane replacements
Abstract
The tympanic membrane (TM), is a thin tissue lying at the intersection of the outer and the middle ear. TM perforations caused by traumas and infections often result in a conductive hearing loss. Tissue engineering has emerged as a promising approach for reconstructing the damaged TM by replicating the native material characteristics. In this regard, chitin nanofibrils (CN), a polysaccharide-derived nanomaterial, is known to exhibit excellent biocompatibility, immunomodulation and antimicrobial activity, thereby imparting essential qualities for an optimal TM regeneration. This work investigates the application of CN as a nanofiller for poly(ethylene oxide terephthalate)/poly(butylene terephthalate) (PEOT/PBT) copolymer to manufacture clinically suitable TM scaffolds using electrospinning and fused deposition modelling. The inclusion of CN within the PEOT/PBT matrix showed a three-fold reduction in the corresponding electrospun fiber diameters and demonstrated a significant improvement in the mechanical properties required for TM repair. Furthermore, in vitro biodegradation assay highlighted a favorable influence of CN in accelerating the scaffold degradation over a period of one year. Finally, the oto- and cytocompatibility response of the nanocomposite substrates corroborated their biological relevance for the reconstruction of perforated eardrums.