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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Walther, Thomas
University of Sheffield
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (13/13 displayed)
- 2022Think outside the boxcitations
- 2022Long-Term Outcomes after Aortic Valve and Root Replacement in a Very High-Risk Populationcitations
- 2021Identity of the local and macroscopic dynamic elastic responses in supercooled 1-propanolcitations
- 2017Impact of buffer gas quenching on the 1S0 → 1P1 ground-state atomic transition in nobeliumcitations
- 2017Study of phase separation in an InGaN alloy by electron energy loss spectroscopy in an aberration corrected monochromated scanning transmission electron microscopecitations
- 2017Impact of buffer gas quenching on the $^1S_0 → ^1P_1$ ground-state atomic transition in nobeliumcitations
- 2017Impact of buffer gas quenching on the $^1S_0$ $to$ $^1P_1$ ground-state atomic transition in nobeliumcitations
- 2014A laser locked Fabry-Perot etalon with 3 cm/s stability for spectrograph calibrationcitations
- 2012Characterization of thickness, elemental distribution and band-gap properties in AlGaN/GaN quantum wells by aberration-corrected TEM/STEMcitations
- 2012Characterization of InGaN/GaN epitaxial layers by aberration corrected TEM/STEMcitations
- 2011Nanoscale EELS analysis of elemental distribution and band-gap properties in AlGaN epitaxial layerscitations
- 2010Electron microscopy of AlGaN-based multilayers for UV laser devices
- 2006Microstructural analysis of lignocellulosic fiber networkscitations
Places of action
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article
Think outside the box
Abstract
<p>3D bioprinting – the fabrication of geometrically complex 3D structures from biocompatible materials containing living cells using additive manufacturing technologies – is a rapidly developing research field with a broad range of potential applications in fundamental research, regenerative medicine and industry. Currently, research into 3D bioprinting is mostly focused on new therapeutic concepts for the treatment of injured or degenerative tissue by fabrication of functional tissue equivalents or disease models, utilizing mammalian cells. However, 3D bioprinting also has an enormous potential in biotechnology. Due to the defined spatial arrangement of biologically active (non-mammalian) cells in a biomaterial matrix, reaction compartments can be designed according to specific needs, or co-cultures of different cell types can be realized in a highly organized manner to exploit cell-cell interactions. Thus, 3D bioprinting technology can enable new biotechnological concepts, for example, by implementing perfusion systems while protecting shear sensitive cells or performing cascaded bioreactions. Here, we review the use of 3D bioprinting to manufacture defined 3D microenvironments for biotechnological applications using bacteria, fungi, microalgae, plant cells and co-cultures of different cell types. We discuss recent approaches to apply 3D bioprinting in biotechnological applications and – as it is a particular challenge – concepts for the real-time monitoring of the physiological state, growth and metabolic activity of the embedded cells in 3D bioprinted constructs. With these insights, we outline new applications of 3D bioprinting in biotechnology, engineered living materials and space research.</p>