| People | Locations | Statistics |
|---|---|---|
| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Estrela, Pedro
University of Bath
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (17/17 displayed)
- 2021CRISPR-based electrochemical sensor for COVID-19 diagnostics
- 2021Graphene enabled low-noise surface chemistry for multiplexed sepsis biomarker detection in whole bloodcitations
- 2020Electrochemical ELISA Protein Biosensing in Undiluted Serum Using a Polypyrrole-Based Platformcitations
- 2019A PNA-based Lab-on-PCB diagnostic platform for rapid and high sensitivity DNA quantificationcitations
- 2019Reduced Graphene-Oxide Transducers for Biosensing Applications Beyond the Debye-Screening Limitcitations
- 2019In-situ synthesis of 3D ultra-small gold augmented graphene hybrid for highly sensitive electrochemical binding capabilitycitations
- 2019Multiplexed Electrochemical Platform for sepsis Diagnostics
- 2017Raman and Mössbauer spectroscopic studies of tungsten doped Ni–Zn nano ferritecitations
- 2017Nanomaterial fungicides: In vitro and in vivo antimycotic activity of cobalt and nickel nanoferrites on phytopathogenic fungicitations
- 2016Electrochemical biosensors and nanobiosensorscitations
- 2016Inexpensive and fast pathogenic bacteria screening using field-effect transistorscitations
- 2016Inexpensive and fast pathogenic bacteria screening using field-effect transistorscitations
- 2016Aptamer-MIP hybrid receptor for highly sensitive electrochemical detection of prostate specific antigencitations
- 2011Room temperature processed ISFETs based on amorphous semiconductors oxides
- 2002High pressure transport study of non-Fermi liquid behaviour in U2Pt2In and U3Ni3Sn4
- 2002Pressure-induced recovery of the Fermi-liquid state in the non-Fermi liquid material U2Pt2Incitations
- 2000Possible non-Fermi-liquid behaviour in URh1/3Ni2/3Alcitations
Places of action
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article
A PNA-based Lab-on-PCB diagnostic platform for rapid and high sensitivity DNA quantification
Abstract
We report the development of a Lab-on-PCB DNA diagnostic platform, exploiting peptide nucleic acid (PNA) sequences as probes. The study demonstrates the optimization and characterization of two commercial PCB manufacturing gold electroplating processes for biosensing applications. Using an optimized ratio of PNA with a spacer molecule (MCH), the lowest limit of detection (LoD) to date for PCB-based DNA biosensors of 57 fM is reported. The study also showcases a fully integrated Lab-on-PCB microsystem designed for rapid detection, which employs PCB-integrated sample delivery, achieving DNA quantification in the 0.1–100 pM range for 5 μL samples analyzed within 5 min under continuous flow. The demonstrated biosensor proves the capability of PCB-based DNA biosensors for high sensitivity and paves the way for their integration in Lab-on-PCB DNA diagnostic microsystems.