| People | Locations | Statistics |
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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Ibáñez, Elena
Universitat Autònoma de Barcelona
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (17/17 displayed)
- 2023Surface Modified β-Ti-18Mo-6Nb-5Ta (wt%) Alloy for Bone Implant Applications:citations
- 2023Surface Modified β-Ti-18Mo-6Nb-5Ta (wt%) Alloy for Bone Implant Applications: Composite Characterization and Cytocompatibility Assessment
- 2022Biodegradable porous FeMn(-xAg) alloys:citations
- 2020Food-safe process for high recovery of flavonoids from cocoa beans: Antioxidant and HPLC-DAD-ESI-MS/MS analysiscitations
- 2018Cytocompatibility assessment of Ti-Zr-Pd-Si-(Nb) alloys with low Young's modulus, increased hardness, and enhanced osteoblast differentiation for biomedical applications
- 2017Study of Galfenol direct cytotoxicity and remote microactuation in cellscitations
- 2017Mechanical properties, corrosion performance and cell viability studies on newly developed porous Fe-Mn-Si-Pd alloyscitations
- 2016Effect of surface modifications of Ti40Zr10Cu38Pd12 bulk metallic glass and Ti-6Al-4V alloy on human osteoblasts in vitro biocompatibilitycitations
- 2016Novel Fe-Mn-Si-Pd alloys: Insights into mechanical, magnetic, corrosion resistance and biocompatibility performancescitations
- 2015Nanostructured Ti-Zr-Pd-Si-(Nb) bulk metallic composites: Novel biocompatible materials with superior mechanical strength and elastic recoverycitations
- 2015Nanostructured Ti-Zr-Pd-Si-(Nb) bulk metallic composites : novel biocompatible materials with superior mechanical strength and elastic recoverycitations
- 2014In vitro biocompatibility assessment of Ti40Cu38Zr10Pd12 bulk metallic glasscitations
- 2013On the biodegradability, mechanical behavior, and cytocompatibility of amorphous Mg72Zn23Ca5 and crystalline Mg70Zn23Ca5Pd2 alloys as temporary implant materialscitations
- 2013Novel Ti-Zr-Hf-Fe nanostructured alloy for biomedical applicationscitations
- 2012Efficient biofunctionalization of polysilicon barcodes for adhesion to the zona pellucida of mouse embryoscitations
- 2012Improved mechanical performance and delayed corrosion phenomena in biodegradable Mg-Zn-Ca alloys through Pd-alloyingcitations
- 2011Supercritical CO2 impregnation of lactulose on chitosan: A comparison between scaffolds and microspheres formcitations
Places of action
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article
Study of Galfenol direct cytotoxicity and remote microactuation in cells
Abstract
© 2017 Elsevier Ltd Remote microactuators are of great interest in biology and medicine as minimally-invasive tools for cellular stimulation. Remote actuation can be achieved by active magnetostrictive transducers which are capable of changing shape in response to external magnetic fields thereby creating controlled displacements. Among the magnetostrictive materials, Galfenol, the multifaceted iron-based smart material, offers high magnetostriction with robust mechanical properties. In order to explore these capabilities for biomedical applications, it is necessary to study the feasibility of material miniaturization in standard fabrication processes as well as evaluate the biocompatibility. Here we develop a technology to fabricate, release, and suspend Galfenol-based microparticles, without affecting the integrity of the material. The morphology, composition and magnetic properties of the material itself are characterized. The direct cytotoxicity of Galfenol is evaluated in vitro using human macrophages, osteoblast and osteosarcoma cells. In addition, cytotoxicity and actuation of Galfenol microparticles in suspension are evaluated using human macrophages. The biological parameters analyzed indicate that Galfenol is not cytotoxic, even after internalization of some of the particles by macrophages. The microparticles were remotely actuated forming intra- and extracellular chains that did not impact the integrity of the cells. The results propose Galfenol as a suitable material to develop remote microactuators for cell biology studies and intracellular applications.