People | Locations | Statistics |
---|---|---|
Naji, M. |
| |
Motta, Antonella |
| |
Aletan, Dirar |
| |
Mohamed, Tarek |
| |
Ertürk, Emre |
| |
Taccardi, Nicola |
| |
Kononenko, Denys |
| |
Petrov, R. H. | Madrid |
|
Alshaaer, Mazen | Brussels |
|
Bih, L. |
| |
Casati, R. |
| |
Muller, Hermance |
| |
Kočí, Jan | Prague |
|
Šuljagić, Marija |
| |
Kalteremidou, Kalliopi-Artemi | Brussels |
|
Azam, Siraj |
| |
Ospanova, Alyiya |
| |
Blanpain, Bart |
| |
Ali, M. A. |
| |
Popa, V. |
| |
Rančić, M. |
| |
Ollier, Nadège |
| |
Azevedo, Nuno Monteiro |
| |
Landes, Michael |
| |
Rignanese, Gian-Marco |
|
Silva-Correia, J.
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (45/45 displayed)
- 2019Evaluating the effect of elastin in the angiogenic response of silk fibroin 3d printed scaffolds
- 2018Gellan Gum-based luminal fillers for peripheral nerve regeneration: an in vivo study in the rat sciatic nerve repair modelcitations
- 2017Silk-based anisotropical 3D biotextiles for bone regenerationcitations
- 2017Biological performance of cell-encapsulated methacrylated gellan gum-based hydrogels for nucleus pulposus regenerationcitations
- 2017A semiautomated microfluidic platform for real-time investigation of nanoparticles' cellular uptake and cancer cells' trackingcitations
- 2017Anti-angiogenic potential of VEGF blocker dendron loaded on to gellan gum hydrogels for tissue engineering applicationscitations
- 2017Investigation of cell adhesion in chitosan membranes for peripheral nerve regenerationcitations
- 2017Emerging tumor spheroids technologies for 3D in vitro cancer modelingcitations
- 2017Current strategies for treatment of intervertebral disc degeneration: Substitution and regeneration possibilitiescitations
- 2016Meniscal repair: Indications, techniques,and outcomecitations
- 2016Optical Projection Tomography Technique for Image Texture and Mass Transport Studies in Hydrogels Based on Gellan Gumcitations
- 2016The role of arthroscopy in the treatment of degenerative meniscus tearcitations
- 2016Recent progress in gellan gum hydrogels provided by functionalization strategiescitations
- 2016Histology-ultrastructure-biologycitations
- 2016Gellan Gum-based Hydrogels for Tissue Engineering Applicationscitations
- 2015Bilayered silk/silk-nanoCaP scaffolds for osteochondral tissue engineering: In vitro and in vivo assessment of biological performancecitations
- 2015Custom-tailored tissue engineered polycaprolactone scaffolds for total disc replacementcitations
- 2015Acellular Gellan- gum based Bilayered Structures for the Regeneration of Osteochondral Defects: A Preclinical Study
- 2015Biological evaluation of intervertebral disc cells in different formulations of gellan gum-based hydrogelscitations
- 2015Posterior talar process as a suitable cell source for treatment of cartilage and osteochondral defects of the taluscitations
- 2014In vivo biofunctional evaluation of hydrogels for disc regenerationcitations
- 2014Current concepts: Tissue engineering and regenerative medicine applications in the ankle jointcitations
- 2014Fabrication methods of tissue engineering scaffolds
- 2014Gellan gum-based hydrogel bilayered scaffolds for osteochondral tissue engineeringcitations
- 2013Biocompatibility evaluation of ionic- and photo-crosslinked methacrylated gellan gum hydrogels: In vitro and in vivo studycitations
- 2013Tissue engineering strategies applied in the regeneration of the human intervertebral diskcitations
- 2013Hydrogels in acellular and cellular strategies for intervertebral disc regenerationcitations
- 2013Erratum to Migration of "bioabsorbable" screws in ACL repair. How much do we know? A systematic review (Knee Surg Sports Traumatol Arthrosc, 10.1007/s00167-013-2414-2)
- 2013The meniscus: Basic sciencecitations
- 2013Migration of "bioabsorbable" screws in ACL repair. How much do we know? A systematic reviewcitations
- 2013Development of nanofiber-reinforced hydrogel scaffolds for nucleus pulposus regeneration by a combination of electrospinning and spraying techniquecitations
- 2013Future trends in the treatment of meniscus lesions: From repair to regenerationcitations
- 2013Bioactive macro/micro porous silk fibroin/nano-sized calcium phosphate scaffolds with potential for bone-tissue-engineering applicationscitations
- 2013Biomechanical and cellular segmental characterization of human meniscus: Building the basis for Tissue Engineering therapiescitations
- 2013Rheological and mechanical properties of acellular and cell-laden methacrylated gellan gum hydrogelscitations
- 2012Cell-loaded gellan gum-based hydrogels for nucleus pulposus regeneration
- 2012Evaluation of different formulations of gellan gum-based hydrogels for tissue engineering of intervertebral disc
- 2012Gellan gum-based bilayered scaffolds for application in osteochondral tissue engineering
- 2012The effect of different defects and hydrogels for nucleus replacements on the biomechanical response of the intervertebral disc
- 2012Microparticles loaded Gellan gum hydrogel matrices: engineering tissues for nucleus pulposus regeneration
- 2012Functionalisation of methacrylated gellan gum hydrogels by anti-angiogenic dendrons
- 2012Mechanical performance and biocompatibility study of methacrylated Gellan gum hydrogels with potential for nucleus pulposus regeneration
- 2012Novel bilayered Gellan gum/Gellan gum-hydroxyapatite scaffolds for osteochondral tissue engineering applications
- 2012Development of macro/micro porous silk fibroin scaffolds with nano-sized calcium phosphate particles for bone tissue engineering
- 2011NOVEL GELLAN GUM HYDROGELS FOR TISSUE ENGINEERING OF INTERVERTEBRAL DISC
Places of action
Organizations | Location | People |
---|
article
Silk-based anisotropical 3D biotextiles for bone regeneration
Abstract
<p>Bone loss in the craniofacial complex can been treated using several conventional therapeutic strategies that face many obstacles and limitations. In this work, novel three-dimensional (3D) biotextile architectures were developed as a possible strategy for flat bone regeneration applications. As a fully automated processing route, this strategy as potential to be easily industrialized. Silk fibroin (SF) yarns were processed into weft-knitted fabrics spaced by a monofilament of polyethylene terephthalate (PET). A comparative study with a similar 3D structure made entirely of PET was established. Highly porous scaffolds with homogeneous pore distribution were observed using micro-computed tomography analysis. The wet state dynamic mechanical analysis revealed a storage modulus In the frequency range tested, the storage modulus values obtained for SF-PET scaffolds were higher than for the PET scaffolds. Human adipose-derived stem cells (hASCs) cultured on the SF-PET spacer structures showed the typical pattern for ALP activity under osteogenic culture conditions. Osteogenic differentiation of hASCs on SF-PET and PET constructs was also observed by extracellular matrix mineralization and expression of osteogenic-related markers (osteocalcin, osteopontin and collagen type I) after 28 days of osteogenic culture, in comparison to the control basal medium. The quantification of convergent macroscopic blood vessels toward the scaffolds by a chick chorioallantoic membrane assay, showed higher angiogenic response induced by the SF-PET textile scaffolds than PET structures and gelatin sponge controls. Subcutaneous implantation in CD-1 mice revealed tissue ingrowth's accompanied by blood vessels infiltration in both spacer constructs. The structural adaptability of textile structures combined to the structural similarities of the 3D knitted spacer fabrics to craniofacial bone tissue and achieved biological performance, make these scaffolds a possible solution for tissue engineering approaches in this area.</p>