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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Foss, Morten
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (17/17 displayed)
- 2023Comment on “Which fraction of stone wool fibre surface remains uncoated by binder? A detailed analysis by time-of-flight secondary ion mass spectrometry and X-ray photoelectron spectroscopy” by Hirth et al., 2021, RSC Adv., 11, 39545, DOI: 10.1039/d1ra06251dcitations
- 2023Thermochemical oxidation of commercially pure titanium; controlled formation of robust white titanium oxide layers for biomedical applicationscitations
- 2023Thermochemical oxidation of commercially pure titanium; controlled formation of robust white titanium oxide layers for biomedical applications.citations
- 2022Local Release of Strontium from Sputter-Deposited Coatings at Implants Increases the Strontium-to-Calcium Ratio in Peri-implant Bonecitations
- 2022Local Release of Strontium from Sputter-Deposited Coatings at Implants Increases the Strontium-to-Calcium Ratio in Peri-implant Bonecitations
- 2022The dissolution of stone wool fibers with sugar-based binder and oil in different synthetic lung fluidscitations
- 2021Post-treatments of polydopamine coatings influence cellular responsecitations
- 2018A comparative in vivo study of strontium-functionalized and SLActive (TM) implant surfaces in early bone healingcitations
- 2017Early stage dissolution characteristics of aluminosilicate glasses with blast furnace slag- and fly-ash-like compositionscitations
- 2015Response of MG63 osteoblast-like cells to ordered nanotopographies fabricated using colloidal self-assembly and glancing angle depositioncitations
- 2015Modulation of Human Mesenchymal Stem Cell Behavior on Ordered Tantalum Nanotopographies Fabricated Using Colloidal Lithography and Glancing Angle Depositioncitations
- 2015Low-aspect ratio nanopatterns on bioinert alumina influence the response and morphology of osteoblast-like cellscitations
- 2012Temperature-induced ultradense PEG polyelectrolyte surface grafting provides effective long-term bioresistance against mammalian cells, serum, and whole bloodcitations
- 2011Growth characteristics of inclined columns produced by Glancing Angle Deposition (GLAD) and colloidal lithographycitations
- 2010Synthesis of functional nanomaterials via colloidal mask templating and glancing angle deposition (GLAD)”
- 2009Polycaprolactone nanomesh cultured with hMSC evaluated by synchrotron tomography
- 2009The use of combinatorial topographical libraries for the screening of enhanced osteogenic expression and mineralizationcitations
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article
Low-aspect ratio nanopatterns on bioinert alumina influence the response and morphology of osteoblast-like cells
Abstract
<p>Topographical features on the nanometer scale are known to influence cellular behavior. The response of specific cell types to various types of surface structures is currently still being investigated. Alumina ceramics play an important role as biomaterials, e.g., in medical and dental applications. In this study, we investigated the influence of nanoscale surface features with low aspect ratio (<0.1) on the response of osteoblast-like MG-63 cells. To this end, low-energy ion irradiation was employed to produce shallow nanoscale ripple patterns on Al2O3(0001) surfaces with lateral periodicities of 24 nm and 179 nm and heights of only 0.7 and 11.5 nm, respectively. The nanopatterning was found to increase the proliferation of MG-63 cells and may lead to pseudopodia alignment along the ripples. Furthermore, focal adhesion behavior and cell morphology were analyzed. We found that MG-63 cells are able to recognize surface nanopattems with extremely low vertical variations of less than 1 nm. In conclusion, it is shown that surface topography in the sub-nm range significantly influences the response of osteoblast-like cells. (c) 2015 Elsevier Ltd. All rights reserved.</p>