| People | Locations | Statistics |
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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Gengenbach, Thomas
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (15/15 displayed)
- 2024Interpretation of Complex X-ray Photoelectron Peak Shapes Part II: Case Study of Fe 2p3/2 fitting applied to Austenitic Stainless Steels 316 and 304.citations
- 2020Covalent sizing surface modification as a route to improved interfacial adhesion in carbon fiber-epoxy compositescitations
- 2020Investigating the real-time dissolution of a compositionally complex alloy using inline ICP and correlation with XPScitations
- 2020Real-time dissolution of a compositionally complex alloy using inline ICP and correlation with XPScitations
- 2020Improving the Stability of Ambient-Processed SnO2-Based, Perovskite Solar Cells by UV-Treatment of the Sub-Cellscitations
- 2020Improving the Stability of Ambient processed, SnO2-Based, Perovskite Solar Cells by the UV-treatment of Sub-Cellscitations
- 2019Electrocatalytic CO2 reduction to formate on Cu based surface alloys with enhanced selectivitycitations
- 2019Fiber with Butterfly Wings: Creating Colored Carbon Fibers with Increased Strength, Adhesion, and Reversible Malleabilitycitations
- 2018Morphology and surface properties of high strength siloxane poly(urethane-urea)s developed for heart valve applicationcitations
- 2017Limitations with solvent exchange methods for synthesis of colloidalfullerenescitations
- 2017Reduction of surface fat formation on spray-dried milk powders through emulsion stabilization with λ-carrageenancitations
- 2016Effect of the deformability of guest particles on the tensile strength of tablets from interactive mixturescitations
- 2014Water-dispersible magnetic carbon nanotubes as T2-weighted MRI contrast agentscitations
- 2012One step multifunctional micropatterning of surfaces using asymmetric glow discharge plasma polymerisation
- 2011Characterization of the surface properties of a model pharmaceutical fine powder modified with a pharmaceutical lubricant to improve flow via a mechanical dry coating approachcitations
Places of action
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article
Water-dispersible magnetic carbon nanotubes as T2-weighted MRI contrast agents
Abstract
An efficient MRI T2-weighted contrast agent incorporating a potential liver targeting functionality was synthesized via the combination of superparamagnetic iron oxide (SPIO) nanoparticles with multiwalled carbon nanotubes (MWCNTs). Poly(diallyldimethylammonium chloride) (PDDA) was coated on the surface of acid treated MWCNTs via electrostatic interactions and SPIO nanoparticles modified with a potential targeting agent, lactose-glycine adduct (Lac-Gly), were subsequently immobilized on the surface of the PDDA-MWCNTs. A narrow magnetic hysteresis loop indicated that the product displayed superparamagnetism at room temperature which was further confirmed by ZFC（zero field cooling）/FC（field cooling）curves measured by SQUID. The multifunctional MWCNT-based magnetic nanocomposites showed low cytotoxicity in vitro to HEK293 and Huh7 cell lines. Enhanced T2 relaxivities were observed for the hybrid material (186 mM-1 s-1) in comparison with the pure magnetic nanoparticles (92 mM-1 s-1) due to the capacity of the MWCNTs to “carry” more nanoparticles as clusters. More importantly, after administration of the composite material to an in vivo liver cancer model in mice, a significant increase in tumour to liver contrast ratio (277%) was observed in T2 weighted magnetic resonance images.