Materials Map

Discover the materials research landscape. Find experts, partners, networks.

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The Materials Map is an open tool for improving networking and interdisciplinary exchange within materials research. It enables cross-database search for cooperation and network partners and discovering of the research landscape.

The dashboard provides detailed information about the selected scientist, e.g. publications. The dashboard can be filtered and shows the relationship to co-authors in different diagrams. In addition, a link is provided to find contact information.

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The Materials Map is still under development. In its current state, it is only based on one single data source and, thus, incomplete and contains duplicates. We are working on incorporating new open data sources like ORCID to improve the quality and the timeliness of our data. We will update Materials Map as soon as possible and kindly ask for your patience.

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in Cooperation with on an Cooperation-Score of 37%

Topics

Publications (31/31 displayed)

  • 2024Extracellular matrix mimetic supramolecular hydrogels reinforced with covalent crosslinked mesoporous silica nanoparticlescitations
  • 2024Optimization of a tunable process for rapid production of calcium phosphate microparticles using a droplet-based microfluidic platform1citations
  • 2023Polymer film-based microwell array platform for long-term culture and research of human bronchial organoids5citations
  • 2023Decoupling the role of chemistry and microstructure in hMSCs response to an osteoinductive calcium phosphate ceramic6citations
  • 2023Matrix metalloproteinase degradable, in situ photocrosslinked nanocomposite bioinks for bioprinting applications4citations
  • 2022Sustained local ionic homeostatic imbalance caused by calcification modulates inflammation to trigger heterotopic ossification15citations
  • 2022Assessment of Cell-Material Interactions in Three Dimensions through Dispersed Coaggregation of Microsized Biomaterials into Tissue Spheroids15citations
  • 2021Biomimetic Mechanically Strong One-Dimensional Hydroxyapatite/Poly(d,l-lactide) Composite Inducing Formation of Anisotropic Collagen Matrix45citations
  • 2021Cobalt-containing calcium phosphate induces resorption of biomineralized collagen by human osteoclasts7citations
  • 2021Biodegradable Elastic Sponge from Nanofibrous Biphasic Calcium Phosphate Ceramic as an Advanced Material for Regenerative Medicine29citations
  • 20213D porous Ti6Al4V-beta-tricalcium phosphate scaffolds directly fabricated by additive manufacturing35citations
  • 2021Injectable, self-healing mesoporous silica nanocomposite hydrogels with improved mechanical properties57citations
  • 2020Intestinal Organoid Culture in Polymer Film-Based Microwell Arrays34citations
  • 2017Development of a microfluidic platform integrating high-resolution microstructured biomaterials to study cell-material interactions29citations
  • 2017Deconvoluting the Bioactivity of Calcium Phosphate-Based Bone Graft Substitutes42citations
  • 2017Deconvoluting the Bioactivity of Calcium Phosphate-Based Bone Graft Substitutes:Strategies to Understand the Role of Individual Material Properties42citations
  • 2017Enhancing regenerative approaches with nanoparticles104citations
  • 2016The Effects of Crystal Phase and Particle Morphology of Calcium Phosphates on Proliferation and Differentiation of Human Mesenchymal Stromal Cells23citations
  • 2016Independent effects of the chemical and microstructural surface properties of polymer/ceramic composites on proliferation and osteogenic differentiation of human MSCs34citations
  • 2016Independent effects of the chemical and microstructural surface properties of polymer/ceramic composites on proliferation and osteogenic differentiation of human MSCs34citations
  • 2015Elucidating the individual effects of calcium and phosphate ions on hMSCs by using composite materials63citations
  • 2010Biomimetic calcium phosphate coatings on recombinant spider silk fibres27citations
  • 2009Effects of soluble cobalt and cobalt incorporated into calcium phosphate layers on osteoclast differentiation and activation100citations
  • 2009Angiogenesis in Calcium Phosphate Scaffolds by Inorganic Copper Ion Release209citations
  • 2008Osteoconduction and osteoinduction of low-temperature 3D printed bioceramic implants300citations
  • 2008Comparative in vivo study of six hydroxyapatite-based bone graft substitutes206citations
  • 2007Biological performance in goats of a porous titanium alloy-biphasic calcium phosphate composite41citations
  • 2006Influence of physico-chemical properties, macro- and microstructure on osteoinductive potential of calcium-phosphate ceramics3citations
  • 2006Relevance of osteoinductive biomaterials in critical-sized orthotopic defect145citations
  • 20053D microenvironment as essential element for osteoinduction by biomaterials541citations
  • 2004Influence of octacalcium phosphate coating on osteoinductive properties of biomaterials146citations

Places of action

Chart of shared publication
Baker, Matthew
1 / 3 shared
Zengin, Aygul
3 / 3 shared
Hafeez, Shahzad
1 / 3 shared
Van Rijt, Sabine
1 / 2 shared
Selsouli, Y. Alaoui
1 / 1 shared
Birgani, Zeinab Tahmasebi
3 / 3 shared
Viecelli, Y.
1 / 2 shared
Bohner, M.
1 / 4 shared
Chacón, Víctor Pablo Galván
3 / 3 shared
Eischen-Loges, Maria
1 / 1 shared
Rho, Hoon Suk
1 / 2 shared
Döbelin, N.
1 / 3 shared
Stähli, C.
1 / 2 shared
Lapointe, Vanessa
3 / 5 shared
Baptista, Danielle
1 / 2 shared
Iriondo, C.
1 / 2 shared
Wolfs, Tim
1 / 2 shared
Van Blitterswijk, Clemens A.
11 / 21 shared
Skarp, K. P.
1 / 2 shared
Stylianidis, V.
1 / 2 shared
Gubbins, E.
1 / 4 shared
Passanha, Fiona Rosaleen
1 / 1 shared
Giselbrecht, Stefan
3 / 14 shared
Rottier, R. J.
1 / 2 shared
Knoops, Kèvin
2 / 3 shared
Widowski, H.
1 / 2 shared
Truckenmüller, Roman
5 / 14 shared
Reynaert, Niki
1 / 1 shared
De Melo Pereira, Daniel
4 / 4 shared
Yuan, H.
1 / 7 shared
Vermeulen, Steven
1 / 1 shared
Li, Jiaping
5 / 5 shared
Van Rijt, Sabine Helena
3 / 4 shared
Teixeira, Filipa Castro
1 / 1 shared
Mota, Carlos
1 / 27 shared
Baker, Matthew B.
1 / 11 shared
Feliciano, Antonio
1 / 3 shared
Beucken, Jeroen J. J. P. Van Den
1 / 1 shared
Seeherman, Howard
1 / 1 shared
Schoenecker, Jonathan G.
1 / 1 shared
Witte, Frank
1 / 10 shared
Maazouz, Yassine
1 / 8 shared
Bohner, Marc
1 / 3 shared
Ginebra, Mp
1 / 289 shared
Fois, Maria Gabriella
1 / 1 shared
Moroni, Lorenzo
2 / 43 shared
Roumans, Nadia
1 / 1 shared
Mouser, Vivian Hilda Maria
1 / 1 shared
Zhang, Yonggang
2 / 2 shared
Schumacher, Matthias
1 / 11 shared
Soleimani, Mohammad
1 / 4 shared
Giacomini, Francesca
1 / 2 shared
Friedrich, Heiner
1 / 10 shared
Yuan, Huipin
4 / 5 shared
Chandrakar, Amit
1 / 2 shared
Olim Castro, João Pedro
1 / 1 shared
Hueber, Rui
1 / 1 shared
Lopez-Iglesias, Carmen
1 / 1 shared
Kakni, Panagiota
1 / 1 shared
Provaggi, E.
1 / 3 shared
Barata, David
3 / 3 shared
Galvan-Chacon, Victor Pablo
1 / 1 shared
Dobelin, Nicola
1 / 2 shared
Stahli, Christoph
1 / 2 shared
Barralet, Jake
2 / 2 shared
Danoux, Charlene
1 / 1 shared
Xu, Xin
2 / 4 shared
Sun, Lanying
2 / 2 shared
Zhang, Jingwei
2 / 2 shared
Wang, Qibao
2 / 2 shared
Danoux, Charlene B.
2 / 2 shared
Bao, Chongyun
2 / 2 shared
Truckenmuller, Roman
1 / 2 shared
Pereira, Daniel
1 / 1 shared
Othman, Z.
1 / 1 shared
Barralet, Jake E.
2 / 4 shared
Barralet, J. E.
1 / 1 shared
Habibovic, P.
1 / 5 shared
Reis, Rui L.
1 / 189 shared
Rodrigues, A. I.
1 / 10 shared
Bassett, David C.
2 / 5 shared
Danoux, Charlène B. S. S.
1 / 1 shared
Blitterswijk, Clemens A. Van
2 / 2 shared
Rodrigues, Ana I.
1 / 1 shared
Othman, Ziryan
1 / 1 shared
Reis, Rui Luís
1 / 1359 shared
Van Blitterswijk, C. A.
1 / 10 shared
Bassett, D. C.
1 / 2 shared
Danoux, Cbss
1 / 1 shared
Blom, Tobias
1 / 1 shared
Yang, Liang
1 / 3 shared
Johansson, Jan
1 / 4 shared
Hedhammar, My
1 / 2 shared
Leifer, Klaus
1 / 14 shared
Patntirapong, Somying
1 / 1 shared
Hauschka, Peter V.
1 / 1 shared
Gbureck, Uwe
2 / 16 shared
Doillon, Charles J.
2 / 2 shared
Gerard, Catherine
1 / 1 shared
Vorndran, Elke
1 / 4 shared
Dolcini, Laura
1 / 1 shared
Juhl, Maria V.
1 / 1 shared
Theilgaard, Naseem
1 / 1 shared
Kruyt, Moyo C.
1 / 3 shared
Martinetti, Roberta
1 / 2 shared
Clyens, Stuart
1 / 3 shared
Wijn, Joost R. De
1 / 1 shared
Wilson, Clayton E.
1 / 1 shared
Groot, Klass De
1 / 1 shared
Doel, Mirella Van Den
1 / 1 shared
Groot, K. De
4 / 4 shared
Sees, Tm
2 / 2 shared
Doel, M. Van Den
1 / 1 shared
Meijer, G.
2 / 4 shared
Valk, Cm Van Der
2 / 2 shared
Chart of publication period
2024
2023
2022
2021
2020
2017
2016
2015
2010
2009
2008
2007
2006
2005
2004

Co-Authors (by relevance)

  • Baker, Matthew
  • Zengin, Aygul
  • Hafeez, Shahzad
  • Van Rijt, Sabine
  • Selsouli, Y. Alaoui
  • Birgani, Zeinab Tahmasebi
  • Viecelli, Y.
  • Bohner, M.
  • Chacón, Víctor Pablo Galván
  • Eischen-Loges, Maria
  • Rho, Hoon Suk
  • Döbelin, N.
  • Stähli, C.
  • Lapointe, Vanessa
  • Baptista, Danielle
  • Iriondo, C.
  • Wolfs, Tim
  • Van Blitterswijk, Clemens A.
  • Skarp, K. P.
  • Stylianidis, V.
  • Gubbins, E.
  • Passanha, Fiona Rosaleen
  • Giselbrecht, Stefan
  • Rottier, R. J.
  • Knoops, Kèvin
  • Widowski, H.
  • Truckenmüller, Roman
  • Reynaert, Niki
  • De Melo Pereira, Daniel
  • Yuan, H.
  • Vermeulen, Steven
  • Li, Jiaping
  • Van Rijt, Sabine Helena
  • Teixeira, Filipa Castro
  • Mota, Carlos
  • Baker, Matthew B.
  • Feliciano, Antonio
  • Beucken, Jeroen J. J. P. Van Den
  • Seeherman, Howard
  • Schoenecker, Jonathan G.
  • Witte, Frank
  • Maazouz, Yassine
  • Bohner, Marc
  • Ginebra, Mp
  • Fois, Maria Gabriella
  • Moroni, Lorenzo
  • Roumans, Nadia
  • Mouser, Vivian Hilda Maria
  • Zhang, Yonggang
  • Schumacher, Matthias
  • Soleimani, Mohammad
  • Giacomini, Francesca
  • Friedrich, Heiner
  • Yuan, Huipin
  • Chandrakar, Amit
  • Olim Castro, João Pedro
  • Hueber, Rui
  • Lopez-Iglesias, Carmen
  • Kakni, Panagiota
  • Provaggi, E.
  • Barata, David
  • Galvan-Chacon, Victor Pablo
  • Dobelin, Nicola
  • Stahli, Christoph
  • Barralet, Jake
  • Danoux, Charlene
  • Xu, Xin
  • Sun, Lanying
  • Zhang, Jingwei
  • Wang, Qibao
  • Danoux, Charlene B.
  • Bao, Chongyun
  • Truckenmuller, Roman
  • Pereira, Daniel
  • Othman, Z.
  • Barralet, Jake E.
  • Barralet, J. E.
  • Habibovic, P.
  • Reis, Rui L.
  • Rodrigues, A. I.
  • Bassett, David C.
  • Danoux, Charlène B. S. S.
  • Blitterswijk, Clemens A. Van
  • Rodrigues, Ana I.
  • Othman, Ziryan
  • Reis, Rui Luís
  • Van Blitterswijk, C. A.
  • Bassett, D. C.
  • Danoux, Cbss
  • Blom, Tobias
  • Yang, Liang
  • Johansson, Jan
  • Hedhammar, My
  • Leifer, Klaus
  • Patntirapong, Somying
  • Hauschka, Peter V.
  • Gbureck, Uwe
  • Doillon, Charles J.
  • Gerard, Catherine
  • Vorndran, Elke
  • Dolcini, Laura
  • Juhl, Maria V.
  • Theilgaard, Naseem
  • Kruyt, Moyo C.
  • Martinetti, Roberta
  • Clyens, Stuart
  • Wijn, Joost R. De
  • Wilson, Clayton E.
  • Groot, Klass De
  • Doel, Mirella Van Den
  • Groot, K. De
  • Sees, Tm
  • Doel, M. Van Den
  • Meijer, G.
  • Valk, Cm Van Der
OrganizationsLocationPeople

article

3D microenvironment as essential element for osteoinduction by biomaterials

  • Meijer, G.
  • Habibovic, Pamela
  • Groot, K. De
  • Yuan, Huipin
  • Van Blitterswijk, Clemens A.
  • Valk, Cm Van Der
Abstract

<p>In order to unravel the mechanism of osteoinduction by biomaterials, in this study we investigated the influence of the specific surface area on osteoinductive properties of two types of calcium phosphate ceramics. Different surface areas of the ceramics were obtained by varying their sintering temperatures.</p><p>Hydroxyapatite (HA) ceramic was sintered at 1150 and 1250degreesC. Biphasic calcium phosphate (BCP) ceramic, consisting of HA and beta-tricalcium phosphate (beta-TCP), was sintered at 1100, 1150 and 1200degreesC.</p><p>Changes in sintering temperature did not influence the chemistry of the ceramics; HA remained pure after sintering at different temperatures and the weight ratio of HA and beta-TCP in the BCP was independent of the temperature as well. Similarly, macroporosity of the ceramics was unaffected by the changes of the sintering temperature. However, microporosity (pore diameter &lt; 10 mum) significantly decreased with increasing sintering temperature. In addition to the decrease of the microporosity, the crystal size increased with increasing sintering temperature. These two effects resulted in a significant decrease of the specific surface area of the ceramics with increasing sintering temperatures.</p><p>Samples of HA1150, HA1250, BCP1100, BCP1150 and BCP1200 were implanted in the back muscles of Dutch milk goats and harvested at 6 and 12 weeks post implantation. After explantation, histomorphometrical analysis was performed on all implants.</p><p>All implanted materials except HA1250 induced bone. However, large variations in the amounts of induced bone were observed between different materials and between individual animals.</p><p>Histomorphometrical results showed that the presence of micropores within macropore walls is necessary to make a material osteoinductive. We postulate that introduction of microporosity within macropores, and consequent increase of the specific surface area, affects the interface dynamics of the ceramic in such a way that relevant cells are triggered to differentiate into the osteogenic lineage. (C) 2004 Elsevier Ltd. All rights reserved.</p>

Topics
  • impedance spectroscopy
  • pore
  • surface
  • ceramic
  • Calcium
  • biomaterials
  • sintering