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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Kim, H.
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (22/22 displayed)
- 2024Stabilization of halide perovskites with silicon compounds for optoelectronic, catalytic, and bioimaging applicationscitations
- 2023Compressive effects in melting of palladium thin films studied by ultrafast x-ray diffraction
- 2023Ti3C2 MXene as additive for low‐cost textile supercapacitors with enhanced electrical performancecitations
- 2022Nanoemulsions prepared from mountain ginseng-mediated gold nanoparticles and silydianin increase the anti-inflammatory effects by regulating NF-κB and MAPK signaling pathways.citations
- 2022Effect of nitriding pre-treatment on the tribocorrosion behavior of physical vapor deposition-coated tool steelcitations
- 2021On the low cycle fatigue response of CoCrNiFeMn high entropy alloy with ultra-fine grain structurecitations
- 2021Metastability engineering of partially recrystallized C-doped non-equiatomic CoCrFeNiMo medium-entropy alloycitations
- 2020Box-Behnken-Design based optimization strategy for alkaline pretreatment of palm oil mill effluent for producing reducing sugarcitations
- 2020Production and processing of graphene and related materialscitations
- 2020Conductive polymer work function changes due to residual water: impact of temperature-dependent dielectric constantcitations
- 2020Doped but Stable: Spirobisacridine Hole Transporting Materials for Hysteresis-Free and Stable Perovskite Solar Cellscitations
- 2020Nanoporous High-Entropy Alloy by Liquid Metal Dealloyingcitations
- 2020Gas tungsten arc welding of as-rolled CrMnFeCoNi high entropy alloycitations
- 2020Lithium-oxygen batteries and related systems: Potential, status, and futurecitations
- 2020Proton-transfer-induced 3D/2D hybrid perovskites suppress ion migration and reduce luminance overshootcitations
- 2017Laser-Materials Processing for Energy Storage Applications
- 2016Dynamics of surfactant-driven fracture of particle rafts.citations
- 2016Non-equilibrium microstructure and thermal stability of plasma-sprayed Al-Si coatingscitations
- 2015Hypervelocity nanoparticle impacts on free-standing graphene: a sui generis mode of sputteringcitations
- 2012Investigation of the chemical mixing state of individual Asian dust particles by the combined use of electron probe X-ray microanalysis and Raman microspectrometrycitations
- 2009Size effect investigation on fracturing of asphalt concrete using the cohesive softening Discrete Element Model
- 2005Fluorine-doped tin oxide electrods for lithium batteriescitations
Places of action
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article
Nanoemulsions prepared from mountain ginseng-mediated gold nanoparticles and silydianin increase the anti-inflammatory effects by regulating NF-κB and MAPK signaling pathways.
Abstract
In order to increase the bioavailability of mountain ginseng (MG), gold nanoparticles (MG-AuNPs) were biologically synthesized from MG extract, and an oil-in-water (O/W) nanoemulsion (SMG-AuNEs) was prepared from MG-AuNPs and a phytochemical silydianin. The physical stability of SMG-AuNEs were monitored and optimized in terms of particle size, pH value, zeta potential, and polydispersity index. The chemicostructural properties of the prepared MG-AuNPs and SMG-AuNEs were characterized using various spectrometric and microscopic analyses, such as EDX spectroscopy, FT-IR spectroscopy, and TEM. The effect of both nanomaterial samples on the anti-inflammatory activity and their underlying mechanism was compared in LPS-stimulated RAW 264.7 cells. SMG-AuNEs did not show toxic effects against RAW 264.7 macrophages, HaCaT keratinocytes, and normal dermal fibroblasts. SMG-AuNEs exhibited significantly higher inhibition of pro-inflammatory genes and proteins, including IL-1β, IL-6, and TNF-α, compared with those of MG-AuNPs and silydianin. Western blotting analysis revealed that the MAPK and NF-κB signalings were highly inhibited by SMG-AuNEs treatment. Hence, this study shows that nano-emulsification of gold nanoparticles prepared from MG is a useful method for augmenting the anti-inflammatory potential of MG. This study may serve as a foundation for using MG as a functional ingredient in anti-inflammatory agents. Our results may implicate the use of nanoemulsions to develop new anti-inflammatory products using MG.