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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Swieszkowski, Wojciech
Warsaw University of Technology
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (15/15 displayed)
- 2023In vitro and in vivo degradation behavior of Mg-0.45Zn-0.45Ca (ZX00) screws for orthopedic applicationscitations
- 2023How to control the crystallization of metallic glasses during laser powder bed fusion? Towards part-specific 3D printing of in situ compositescitations
- 2023Microstructure and properties of an AZ61 alloy after extrusion with a forward-backward oscillating die without preheating of the initial billetcitations
- 2023In-depth analysis of the influence of bio-silica filler (Didymosphenia geminata frustules) on the properties of Mg matrix compositescitations
- 2023The combined effect of zinc and calcium on the biodegradation of ultrahigh-purity magnesium implantscitations
- 2023Design of polymeric thin films with nanovolcanoes for trapping hydroxyapatite nanoparticles to promote or inhibit cell proliferation
- 2022In situ alloying of NiTi: Influence of laser powder bed fusion (LBPF) scanning strategy on chemical compositioncitations
- 2022Heat Treatment of NiTi Alloys Fabricated Using Laser Powder Bed Fusion (LPBF) from Elementally Blended Powderscitations
- 2022A comparison of the microstructure-dependent corrosion of dual-structured Mg-Li alloys fabricated by powder consolidation methods: Laser powder bed fusion vs pulse plasma sinteringcitations
- 2022The Role of LPSO Structures in Corrosion Resistance of Mg-Y-Zn Alloyscitations
- 2022How to Control the Crystallization of Metallic Glasses During Laser Powder Bed Fusion? Towards Part-Specific 3d Printing of in Situ Composites
- 2021Investigation into morphological and electromechanical surface properties of reduced-graphene-oxide-loaded composite fibers for bone tissue engineering applications: A comprehensive nanoscale study using atomic force microscopy approachcitations
- 2021Biological and Corrosion Evaluation of In Situ Alloyed NiTi Fabricated through Laser Powder Bed Fusion (LPBF)citations
- 20203D-Printed Drug Delivery Systemscitations
- 20203D-Printed Drug Delivery Systems : The Effects of Drug Incorporation Methods on Their Release and Antibacterial Efficiencycitations
Places of action
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article
In vitro and in vivo degradation behavior of Mg-0.45Zn-0.45Ca (ZX00) screws for orthopedic applications
Abstract
Magnesium (Mg) alloys have become a potential material for orthopedic implants due to their unnecessaryimplant removal, biocompatibility, and mechanical integrity until fracture healing. This study examined the invitro and in vivo degradation of an Mg fixation screw composed of Mg-0.45Zn-0.45Ca (ZX00, in wt.%). With ZX00human-sized implants, in vitro immersion tests up to 28 days under physiological conditions, along with electrochemicalmeasurements were performed for the first time. In addition, ZX00 screws were implanted in thediaphysis of sheep for 6, 12, and 24 weeks to assess the degradation and biocompatibility of the screws in vivo.Using scanning electron microscopy (SEM) coupled with energy dispersive X-ray spectroscopy (EDX), microcomputedtomography (μCT), X-ray photoelectron spectroscopy (XPS), and histology, the surface and crosssectionalmorphologies of the corrosion layers formed, as well as the bone-corrosion-layer-implant interfaces,were analyzed. Our findings from in vivo testing demonstrated that ZX00 alloy promotes bone healing and theformation of new bone in direct contact with the corrosion products. In addition, the same elemental compositionof corrosion products was observed for in vitro and in vivo experiments; however, their elemental distribution andthicknesses differ depending on the implant location. Our findings suggest that the corrosion resistance wasmicrostructure-dependent. The head zone was the least corrosion-resistant, indicating that the production procedurecould impact the corrosion performance of the implant. In spite of this, the formation of new bone and noadverse effects on the surrounding tissues demonstrated that the ZX00 is a suitable Mg-based alloy for temporarybone implants.