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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Costa, Pedro
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (36/36 displayed)
- 2024Application of sound waves during the curing of an acrylic resin and its composites based on short carbon fibers and carbon nanofibers
- 2024Improving Definition of Screen-Printed Functional Materials for Sensing Applicationcitations
- 2024Strategies for Improving Sustainability in the Development of High-Performance Styrenic Block Copolymers by Developing Blends with Cellulose Derivatives
- 2024Towards Sustainable Temperature Sensor Production through CO2-Derived Polycarbonate-Based Composites
- 2024Towards Sustainable Temperature Sensor Production through CO2-Derived Polycarbonate-Based Composites
- 2024Correlation between the electrical and thermal conductivity of acrylonitrile butadiene styrene composites with carbonaceous fillers with different dimensionality
- 2024Stretchable Conductive Inks with Carbon‐Based Fillers for Conformable Printed Electronics
- 2023Ternary Multifunctional Composites with Magnetorheological Actuation and Piezoresistive Sensing Responsecitations
- 2023Poly(3-hydroxybutyrate-co-3-hydroxyvalerate) Blends with Poly(caprolactone) and Poly(lactic acid): A Comparative Studycitations
- 2023Engineering the magnetic properties of acrylonitrile butadiene styrene‐based composites with magnetic nanoparticles
- 2023Beeswax multifunctional composites with thermal-healing capability and recyclabilitycitations
- 2023Rational design of magnetoliposomes for enhanced interaction with bacterial membrane modelscitations
- 2023Graphene Based Printable Conductive Wax for Low‐Power Thermal Actuation in Microfluidic Paper‐Based Analytical Devicescitations
- 2023Acrylonitrile butadiene styrene-based composites with permalloy with tailored magnetic responsecitations
- 2022Crack path and fracture surface analysis of ultrasonic fatigue testing under multiaxial loadings
- 2022Multifunctional touch sensing and antibacterial polymer-based core-shell metallic nanowire composites for high traffic surfacescitations
- 2022Printed 3D gesture recognition thermoformed half sphere compatible with In-Mold electronic applicationscitations
- 2022Multifunctional Touch Sensing and Antibacterial Polymer‐Based Core‐Shell Metallic Nanowire Composites for High Traffic Surfacescitations
- 2022Environmentally friendly conductive screen‐printable inks based on N‐Doped graphene and polyvinylpyrrolidonecitations
- 2022Polyethylene/ Poly(3-hydroxybutyrate-co-3-hydroxyvalerate /Carbon Nanotube Composites for Eco-Friendly Electronic Applicationscitations
- 2022Investigating the thermal stability of metallic and non-metallic nanoparticles using a novel graphene oxide-based transmission electron microscopy heating-membranecitations
- 2022Polyethylene/ poly(3-hydroxybutyrate-co-3-hydroxyvalerate /carbon nanotube composites for eco-friendly electronic applicationscitations
- 2021Machine Learning Optimization for Robotic Welding Parametrizationcitations
- 2020Functional piezoresistive polymer-composites based on polycarbonate and polylactic acid for deformation sensing applicationscitations
- 2020Antimicrobial and antibiofilm properties of fluorinated polymers with embedded functionalized nanodiamondscitations
- 2020All-Printed piezoresistive sensor matrix with organic thin-film transistors as a switch for crosstalk reductioncitations
- 2020Review of Multiaxial Testing for Very High Cycle Fatigue: From ‘Conventional’ to Ultrasonic Machinescitations
- 2019Optimized silk fibroin piezoresistive nanocomposites for pressure sensing applications based on natural polymerscitations
- 2019Optimized silk fibroin piezoresistive nanocomposites for pressure sensing applications based on natural polymerscitations
- 2019Ionic-liquid-based electroactive polymer composites for muscle tissue engineeringcitations
- 2018Polymer nanocomposite-based strain sensors with tailored processability and improved device integrationcitations
- 2015Towards "green" smart materials for force and strain sensors: The case of polyanilinecitations
- 2012Influence of metakaoline on the chloride penetration performance of concrete
- 2012Influence of metakaoline on the chloride penetration performance of concrete
- 2011Production of electroactive filaments by coextrusion
- 2010Recent developments in inorganically filled carbon nanotubes: successes and challengescitations
Places of action
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article
Rational design of magnetoliposomes for enhanced interaction with bacterial membrane models
Abstract
<p>There is a growing need for alternatives to target and treat bacterial infection. Thus, the present work aims to develop and optimize the production of PEGylated magnetoliposomes (MLPs@PEG), by encapsulating superparamagnetic iron oxide nanoparticles (SPIONs) within fusogenic liposomes. A Box–Behnken design was applied to modulate size distribution variables, using lipid concentration, SPIONs amount and ultrasonication time as independent variables. As a result of the optimization, it was possible to obtain MLPs@PEG with a mean size of 182 nm, with polydispersity index (PDI) of 0.19, and SPIONs encapsulation efficiency (%EE) around 76%. Cytocompatibility assays showed that no toxicity was observed in fibroblasts, for iron concentrations up to 400μg/ml. Also, for safe lipid and iron concentrations, no hemolytic effect was detected. The fusogenicity of the nanosystems was first evaluated through lipid mixing assays, based on Förster resonance energy transfer (FRET), using liposomal membrane models, mimicking bacterial cytoplasmic membrane and eukaryotic plasma membrane. It was shown that the hybrid nanosystems preferentially interact with the bacterial membrane model. Confocal microscopy and fluorescence lifetime measurements, using giant unilamellar vesicles (GUVs), validated these results. Overall, the developed hybrid nanosystem may represent an efficient drug delivery system with improved targetability for bacterial membrane.</p>