| People | Locations | Statistics |
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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Briscoe, Wuge H.
University of Bristol
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (27/27 displayed)
- 2022Interfacial complexation of a neutral amphiphilic ‘tardigrade’ co-polymer with a cationic surfactant
- 2022Interfacial complexation of a neutral amphiphilic ‘tardigrade’ co-polymer with a cationic surfactant: Transition from synergy to competitioncitations
- 2022Interfacial complexation of a neutral amphiphilic ‘tardigrade’ co-polymer with a cationic surfactant: Transition from synergy to competitioncitations
- 2022Interfacial complexation of a neutral amphiphilic ‘tardigrade’ co-polymer with a cationic surfactant:Transition from synergy to competition
- 2021Heads or tails:Nanostructure and molecular orientations in organised erucamide surface layerscitations
- 2021Friction at nanopillared polymer surfaces beyond Amontons' laws:Stick-slip amplitude coefficient (SSAC) and multiparametric nanotribological propertiescitations
- 2021Friction at nanopillared polymer surfaces beyond Amontons' lawscitations
- 2021Heads or tailscitations
- 2020Mixed liposomes containing gram-positive bacteria lipidscitations
- 2020Interactions between PAMAM dendrimers and DOPC lipid multilayerscitations
- 2020Synergy, competition, and the “hanging” polymer layer:Interactions between a neutral amphiphilic ‘tardigrade’ comb co-polymer with an anionic surfactant at the air-water interfacecitations
- 2020Synergy, competition, and the “hanging” polymer layer: Interactions between a neutral amphiphilic ‘tardigrade’ comb co-polymer with an anionic surfactant at the air-water interfacecitations
- 2020Multiscale characterisation of single synthetic fibres:Surface morphology and nanomechanical propertiescitations
- 2020Interactions between PAMAM dendrimers and DOPC lipid multilayers:Membrane thinning and structural disordercitations
- 2019Bénard-Marangoni Dendrites upon Evaporation of a Reactive ZnO Nanofluid Dropletcitations
- 2018Surface structure of few layer graphenecitations
- 2017Interfacial and structural characteristics of polyelectrolyte multilayers used as cushions for supported lipid bilayerscitations
- 2016Influence of solvent polarity on the structure of drop-cast electroactive tetra(aniline)-surfactant thin filmscitations
- 2016Influence of solvent polarity on the structure of drop-cast electroactive tetra(aniline)-surfactant thin filmscitations
- 2016Structure of lipid multilayerscitations
- 2016Structure of lipid multilayers:Via drop casting of aqueous liposome dispersionscitations
- 2016Hydrophilic nanoparticles stabilising mesophase curvature at low concentration but disrupting mesophase order at higher concentrationscitations
- 2016Stability of polymersomes prepared by size exclusion chromatography and extrusioncitations
- 2014In situ X-ray reflectivity studies of molecular and molecular-cluster intercalation within purple membrane filmscitations
- 2014In situ X-ray reflectivity studies of molecular and molecular-cluster intercalation within purple membrane filmscitations
- 2011Lamellar nanocomposite films of purple membrane and poly(acrylate)
- 2010Assembly of poly(methacrylate)/purple membrane lamellar nanocomposite films by intercalation and in situ polymerisationcitations
Places of action
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article
Interactions between PAMAM dendrimers and DOPC lipid multilayers
Abstract
<p>Background: Understanding the structure of hybrid nanoparticle-lipid multilayers is of fundamental importance to their bioanalytical applications and nanotoxicity, where nanoparticle-membrane interactions play an important role. Poly(amidoamine) (PAMAM) dendrimers are branched polymeric nanoparticles with potential biomedical applications due to precise tunability of their physicochemical properties. Here, the effect of PAMAM dendrimers (2.9–4.5 nm) with either a hydrophilic amine (NH<sub>2</sub>) or a hydrophobic C<sub>12</sub> chain surface termination on the 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) multilayers has been studied for the first time. Methods: DOPC multilayers were created by the liposome-rupture method via drop-casting dendrimer-liposome dispersions with the dendrimers added at different concentrations and at three different stages. The multilayer structure was evaluated via the analysis of the synchrotron X-ray reflectivity (XRR) curves, obtaining the bilayer d-spacing, the coherence length from the Scherrer (L<sub>s</sub>) analysis of the Bragg peaks, and the paracrystalline disorder parameter (g). Results: Dendrimer addition led to lipid bilayer thinning and more disordered multilayer structures. Larger hydrophobic dendrimers caused greater structural disruption to the multilayers compared to the smaller dendrimers. The smallest, positively charged dendrimers at their highest concentration caused the most pronounced bilayer thinning. The dendrimer-liposome mixing method also affected the multilayer structure due to different dendrimer aggregation involved. Conclusions: These results show the complexity of the effect of dendrimer physicochemical properties and the addition method of dendrimers on the structure of mixed dendrimer-DOPC multilayers. General significance: These insights are useful for fundamental understanding of nanotoxicity and future biomedical application of nanocomposite multilayer materials in which nanoparticles are added for enhanced properties and functionality.</p>