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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Naves, Lucas Zago
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (16/16 displayed)
- 2024Biomechanical behavior of molars restored with direct and indirect restorations in combination with deep margin elevation.citations
- 2023Deep margin elevation
- 2019Effects of Surface Treatments on Mechanics Behavior of Sintered and Pre-sintered Yttria-Stabilized Zirconia and Reliability of Crowns and Abutments Processed by CAD/CAMcitations
- 2019Effects of Surface Treatments on Mechanics Behavior of Sintered and Pre-sintered Yttria-Stabilized Zirconia and Reliability of Crowns and Abutments Processed by CAD/CAMcitations
- 2019Randomized clinical trial on the survival of lithium disilicate posterior partial restorations bonded using immediate or delayed dentin sealing after 3 years of functioncitations
- 2016Effect of radiotherapy, adhesive systems and doxycycline on the bond strength of the dentin-composite interface
- 2015The influence of polymerization type and reinforcement method on flexural strength of acrylic resincitations
- 2014Effect of glass fiber incorporation on flexural properties of experimental compositescitations
- 2014Influence of abutment screw design and surface coating on the bending flexural strength of the implant setcitations
- 2013Influence of chlorhexidine on dentin adhesive interface micromorphology and nanoleakage expression of resin cementscitations
- 2012Mechanical properties of cast commercially pure titanium simulating ceramic firing cyclescitations
- 2012Short-term PTH administration increases dentine apposition and microhardness in micecitations
- 2011Bond strength of fiber posts in different root thirds using resin cementcitations
- 2011Bond strength of fibre glass and carbon fibre posts to the root canal walls using different resin cementscitations
- 2011Surface treatment of glass fiber and carbon fiber postscitations
- 2009Assessment of the polymerization contraction stress of composites photoactivated by halogen light and light-emitting diode
Places of action
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article
Short-term PTH administration increases dentine apposition and microhardness in mice
Abstract
<p>OBJECTIVE: The purpose of this study is to investigate the effects of intermittent parathyroid hormone (PTH) administration on the apposition rate and structural features of dentine from mouse incisors.</p><p>METHODS: Young male A/J Unib mice were treated daily for 6 and 10 days with 40 μg/kg of hPTH 1-34 or a vehicle. Dentine apposition rates measured by fluorescent labels (tetracycline and calcein) and alkaline phosphatase (ALP) plasma levels were evaluated after 6 days of treatment. Knoop microhardness testing and element content measurements in at.% of calcium (Ca), phosphorus (P), oxygen (O), and magnesium (Mg) in the peritubular and intertubular dentine were performed by Energy Dispersive X-ray (EDX) microanalysis via Scanning Electron Microscopy (SEM) after 10 days of treatment.</p><p>RESULTS: Histometric analysis revealed an increase of 5% in the apposition rate of dentine and 25% in the ALP plasma levels in the PTH treated group. In addition, knoop microhardness testing revealed that the animals treated with PTH had a greater microhardness (11%). EDX microanalysis showed that PTH treatment led to increases in P (23%) and Ca (53%) at.% content, as well as the Ca/P ratio (24%) in peritubular dentine. The chemical composition of intertubular dentine did not vary between the groups.</p><p>CONCLUSIONS: These findings indicate that intermittent administration of hPTH (1-34) increases apposition and mineralization of the dentine during young mice incisor formation.</p>