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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Cochis, Andrea
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (17/17 displayed)
- 2024Anticorrosion and Antimicrobial Tannic Acid-Functionalized Ti-Metallic Glass Ribbons for Dental Abutmentcitations
- 2024Anticorrosion and Antimicrobial Tannic Acid-Functionalized Ti-Metallic Glass Ribbons for Dental Abutment
- 2024Multifunctional Sr,Mg doped mesoporous bioactive glass nanoparticles
- 2023Development, Analytical Characterization, and Bioactivity Evaluation of Boswellia serrata Extract-Layered Double Hydroxide Hybrid Compositescitations
- 2023UV-Cured Bio-Based Acrylated Soybean Oil Scaffold Reinforced with Bioactive Glassescitations
- 2023Conferring Antioxidant Activity to an Antibacterial and Bioactive Titanium Surface through the Grafting of a Natural Extractcitations
- 2023Ti$_{40}$Zr$_{10}$Cu$_{36}$Pd$_{14}$ bulk metallic glass as oral implant materialcitations
- 2023Functionalization of a chemically treated Ti6Al4V-ELI alloy with nisin for antibacterial purposescitations
- 2023Ti40Zr10Cu36Pd14 bulk metallic glass as oral implant materialcitations
- 2022Antibacterial activity, cytocompatibility, and thermomechanical stability of Ti40Zr10Cu36Pd14 bulk metallic glasscitations
- 2021Antibacterial, pro-angiogenic and pro-osteointegrative zein-bioactive glass/copper based coatings for implantable stainless steel aimed at bone healingcitations
- 2020Antimicrobial Mechanisms and Effectiveness of Graphene and Graphene-Functionalized Biomaterials. A Scope Reviewcitations
- 2018Reduced bacterial adhesion on ceramics used for arthroplasty applicationscitations
- 2017Composite bone cements for hyperthermia: modeling and characterization of magnetic, calorimetric and in vitro heating propertiescitations
- 2015Bioceramic Materials Show Reduced Pathological Biofilm Formationcitations
- 2015Composite bone cements loaded with a bioactive and ferrimagnetic glass-ceramic: Leaching, bioactivity and cytocompatibilitycitations
- 2014Antibacterial and bioactive nanostructured titanium surfaces for bone integrationcitations
Places of action
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article
Functionalization of a chemically treated Ti6Al4V-ELI alloy with nisin for antibacterial purposes
Abstract
<p>This research aims to define a protocol for nisin adsorption onto Ti6Al4V- Extra Low Interstitial content (ELI) alloy to reduce the risk of peri-implant infections. The substrate is, first, etched to get a nanotextured surface with a high density of acidic hydroxyl groups and then functionalized with the antimicrobial peptide nisin. Nisin adsorption is performed at different pH values, in the range of 5–7. The nisin release in inorganic solutions mimicking physiological or pro-inflammatory conditions is tested. The surfaces are characterized by profilometry, SEM/EDS, contact angle and surface free energy measurements, zeta potential titrations, DLS, XPS, and UV–visible spectroscopy. Effective surface adsorption was achieved and maximized at pH 6. The coated surface has high surface energy suitable for tissue integration and it releases nisin in a time longer than 1 day. As a confirmation of the antibacterial properties due to the nisin adsorption, specimens were incubated with Staphylococcus aureus, whose metabolic activity was reduced by ≈ 70% in comparison to the untreated control, and the number of viable adhered colonies was ≈ 6 times reduced. In conclusion, coupling of nisin to a chemically treated titanium surface is promising for a bioactive and antibacterial surface for tissue integration.</p>