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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Spriano, Silvia
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (17/17 displayed)
- 2024Exploitation of tannic acid as additive for the adhesion enhancement of UV-curable bio-based coatingcitations
- 2024Ce-doped MgO films on AZ31 alloy substrate for biomedical applications: preparation, characterization and testingcitations
- 2024Ce-doped MgO films on AZ31 alloy substrate for biomedical applications: preparation, characterization and testingcitations
- 2024Natural Tannin Layers for the Corrosion Protection of Steel in Contact with Water-Based Mediacitations
- 2024Anticorrosion and Antimicrobial Tannic Acid-Functionalized Ti-Metallic Glass Ribbons for Dental Abutmentcitations
- 2024Anticorrosion and Antimicrobial Tannic Acid-Functionalized Ti-Metallic Glass Ribbons for Dental Abutment
- 2024TEM and zeta potential titration as suitable techniques for investigating the joining of modified ceramic surfacescitations
- 2023Conferring Antioxidant Activity to an Antibacterial and Bioactive Titanium Surface through the Grafting of a Natural Extractcitations
- 2023Functionalization of a chemically treated Ti6Al4V-ELI alloy with nisin for antibacterial purposescitations
- 2023Natural Polyphenols and the Corrosion Protection of Steel: Recent Advances and Future Perspectives for Green and Promising Strategiescitations
- 2022Functionalization with Polyphenols of a Nano-Textured Ti Surface through a High–Amino Acid Medium: A Chemical–Physical and Biological Characterizationcitations
- 2022Advanced characterization of albumin adsorption on a chemically treated surface for osseointegration: an innovative experimental approachcitations
- 2021Effect of various surface modifications on c.p. Ti and Ti6Al4V on the adsorption of proteins relevant for osseointegration and inflammatory response
- 20213D Printing of PDMS-Like Polymer Nanocomposites with Enhanced Thermal Conductivity: Boron Nitride Based Photocuring Systemcitations
- 2019Fatigue resistance of light alloy sheets undergoing eco-friendly chemical milling: metallurgical and chemical aspectscitations
- 2019Studies on cell compatibility, antibacterial behavior, and zeta potential of Ag-containing polydopamine-coated bioactive glass-ceramiccitations
- 2001Electrochemical behaviour of Au-Gd alloys
Places of action
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article
Functionalization of a chemically treated Ti6Al4V-ELI alloy with nisin for antibacterial purposes
Abstract
<p>This research aims to define a protocol for nisin adsorption onto Ti6Al4V- Extra Low Interstitial content (ELI) alloy to reduce the risk of peri-implant infections. The substrate is, first, etched to get a nanotextured surface with a high density of acidic hydroxyl groups and then functionalized with the antimicrobial peptide nisin. Nisin adsorption is performed at different pH values, in the range of 5–7. The nisin release in inorganic solutions mimicking physiological or pro-inflammatory conditions is tested. The surfaces are characterized by profilometry, SEM/EDS, contact angle and surface free energy measurements, zeta potential titrations, DLS, XPS, and UV–visible spectroscopy. Effective surface adsorption was achieved and maximized at pH 6. The coated surface has high surface energy suitable for tissue integration and it releases nisin in a time longer than 1 day. As a confirmation of the antibacterial properties due to the nisin adsorption, specimens were incubated with Staphylococcus aureus, whose metabolic activity was reduced by ≈ 70% in comparison to the untreated control, and the number of viable adhered colonies was ≈ 6 times reduced. In conclusion, coupling of nisin to a chemically treated titanium surface is promising for a bioactive and antibacterial surface for tissue integration.</p>