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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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León, B.
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Topics
Publications (5/5 displayed)
- 2015Extensive studies on biomorphic SiC ceramics properties for medical applications
- 2011Improvement of electrospun polymer fiber meshes pore size by femtosecond laser irradiationcitations
- 2010Surface modification of a biodegradable composite by UV laser ablation: In vitro biological performancecitations
- 2009Silicon-hydroxyapatite bioactive coatings (Si-HA) from diatomaceous earth and silica. Study of adhesion and proliferation of osteoblast-like cellscitations
- 2008Silicon-hydroxyapatite bioactive coatings (Si-HA) from diatomaceous earth and SiO2: study of adhesion and proliferation of osteoblast-like cells
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article
Improvement of electrospun polymer fiber meshes pore size by femtosecond laser irradiation
Abstract
Polymer meshes have recently attracted great attention due to their great variety of aplications in fields such as tissue engineering and drug delivery. Poly( -caprolactone) nanofibers were prepared by electrospinning giving rise to porous meshes. However, for some applications in tissue engineering where, for instance, cell migration into the inner regions of the mesh is aimed, the pore size obtained by conventional techniques is too narrow. To improve the pore size, laser irradiation with femtosecond pulses (i.e., negligible heat diffusion into the polymer material and confined excitation energy) is performed. A detailed study of the influence of the pulse energy, pulse length, and number of pulses on the topography of electrospun fiber meshes has been carried out, and the irradiated areas have been studied by scanning electron microscopy, contact angle measurements and spectroscopic techniques. The results show that using the optimal laser parameters, micropores are formed and the nature of the fibers is preserved. ; European Integrated Project GENOSTEM (LSH-STREP-CT-2003-503161); European Network of Excellence EXPERTISSUES (NMP3-CT-2004-500283); Interreg III Project Proteus (SP1P151/03); Xunta de Galicia (Consolidación 2006/12); Axudas para adquisición de instrumentación científica 2004, PGIDIT04PXI32201IF; Ángeles Alvariño Program; Universidad de Vigo; Portuguese Foundation for Science and Technology for the PhD grant SFRH/BD/24382/2005.