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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Aparicio, Conrado
Universitat Internacional de Catalunya
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (42/42 displayed)
- 2022Relevant aspects of piranha passivation in Ti6Al4V alloy dental meshescitations
- 2021Hybrid Nanocoatings of Self-assembled Organic-Inorganic Amphiphiles for Prevention of Implant Infectionscitations
- 2021Utilizing a degradation prediction pathway system to understand how a novel methacrylate derivative polymer with flipped external ester groups retains physico-mechanical properties following esterase exposurecitations
- 2020A Novel Dental Polymer with a Flipped External Ester Group Design that Resists Degradation via Polymer Backbone Preservationcitations
- 2020Physical-chemical interactions between dental materials surface, salivary pellicle and Streptococcus gordoniicitations
- 2020Harnessing biomolecules for bioinspired dental biomaterialscitations
- 2020Polymeric nanoparticles protect the resin-dentin bonded interface from cariogenic biofilm degradationcitations
- 2019Present and future of tissue engineering scaffolds for dentin-pulp complex regenerationcitations
- 2019Nano-scale modification of titanium implant surfaces to enhance osseointegrationcitations
- 2018Effects of Molecular Weight and Concentration of Poly(Acrylic Acid) on Biomimetic Mineralization of Collagencitations
- 2018In vitro cell response on CP-Ti surfaces functionalized with TGF-β1 inhibitory peptidescitations
- 2017Interfacial degradation of adhesive composite restorations mediated by oral biofilms and mechanical challenge in an extracted tooth model of secondary cariescitations
- 2015Peptide-functionalized zirconia and new zirconia/titanium biocermets for dental applicationscitations
- 2015Biomimetic Mineralization of Recombinamer-Based Hydrogels toward Controlled Morphologies and High Mineral Densitycitations
- 2015Development of tantalum scaffold for orthopedic applications produced by space-holder methodcitations
- 2014Degradation in the dentin-composite interface subjected to multi-species biofilm challengescitations
- 2014Collagen-functionalised titanium surfaces for biological sealing of dental implantscitations
- 2014Assessing near infrared optical properties of ceramic orthodontic brackets using cross-polarization optical coherence tomographycitations
- 2013Bioactive Ceramic and Metallic Surfaces for Bone Engineeringcitations
- 2013Bioactive Ceramic and Metallic Surfaces for Bone Engineeringcitations
- 2012Imaging in vivo secondary caries and ex vivo dental biofilms using cross-polarization optical coherence tomographycitations
- 2012A reproducible oral microcosm biofilm model for testing dental materialscitations
- 2012Quantifying dental biofilm growth using cross-polarization optical coherence tomographycitations
- 2012Mineralization of peptide amphiphile nanofibers and its effect on the differentiation of human mesenchymal stem cellscitations
- 2012Biomimetic mineralization of woven bone-like nanocompositescitations
- 2011Effect of blasting treatment and Fn coating on MG63 adhesion and differentiation on titaniumcitations
- 2009Influence of the height of the external hexagon and surface treatment on fatigue life of commercially pure titanium dental implants
- 2008Oxidized NiTi surfaces enhance differentiation of osteoblast-like cellscitations
- 2007Low elastic modulus metals for joint prosthesiscitations
- 2007The influence of surface energy on competitive protein adsorption on oxidized NiTi surfacescitations
- 2007Electrochemical behaviour of oxidized NiTi shape memory alloys for biomedical applicationscitations
- 2006Bioceramics as nanomaterialscitations
- 2006Development of a biodegradable composite scaffold for bone tissue engineeringcitations
- 2006New oxidation treatment of NiTi shape memory alloys to obtain Ni-free surfaces and to improve biocompatibilitycitations
- 2005Static mechanical properties of hydroxyapatite (HA) powder-filled acrylic bone cementscitations
- 2005Surface characterization of completely degradable composite scaffoldscitations
- 2004Osseointegration of Grit-Blasted and Bioactive Titanium Implants
- 2002Effect of oxygen content on grain growth kinetics of titaniumcitations
- 2002Mechanical performance of acrylic bone cements containing different radiopacifying agentscitations
- 2002Growth of Bioactive Surfaces on Dental Implantscitations
- 2002Human-osteoblast proliferation and differentiation on grit-blasted and bioactive titanium for dental applicationscitations
- 2002Growth of bioactive surfaces on titanium and its alloys for orthopaedic and dental implantscitations
Places of action
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article
Polymeric nanoparticles protect the resin-dentin bonded interface from cariogenic biofilm degradation
Abstract
<p>The objective was to assess doxycycline (Dox) and zinc (Zn) doped nanoparticles' (NPs) potential to protect the resin-dentin interface from cariogenic biofilm. Three groups of polymeric NPs were tested: unloaded, loaded with zinc and with doxycycline. NPs were applied after dentin etching. The disks were exposed to a cariogenic biofilm challenge in a Drip-Flow Reactor during 72 h and 7 d. Half of the specimens were not subjected to biofilm formation but stored 72 h and 7 d. LIVE/DEAD® viability assay, nano-dynamic mechanical assessment, Raman spectroscopy and field emission electron microscopy (FESEM) analysis were performed. The measured bacterial death rates, at 7 d were 46% for the control group, 51% for the undoped-NPs, 32% for Dox-NPs, and 87% for Zn-NPs; being total detected bacteria reduced five times in the Dox-NPs group. Zn-NPs treated samples reached, in general, the highest complex modulus values at the resin-dentin interface over time. Regarding the mineral content, Zn-NPs-treated dentin interfaces showed the highest mineralization degree associated to the phosphate peak and the relative mineral concentration. FESEM images after Zn-NPs application permitted to observe remineralization of the etched and non-resin infiltrated collagen layer, and bacteria were scarcely encountered. The combined antibacterial and remineralizing effects, when Zn-NPs were applied, reduced biofilm formation. Dox-NPs exerted an antibacterial role but did not remineralize the bonded interface. Undoped-NPs did not improve the properties of the interfaces. Application of Zn-doped NPs during the bonding procedure is encouraged. Statement of significance: Application of Zn-doped nanoparticles on acid etched dentin reduced biofilm formation and viability at the resin-dentin interface due to both remineralization and antibacterial properties. Doxycycline-doped nanoparticles also diminished oral biofilm viability, but did not remineralize the resin-dentin interface.</p>