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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Vogt, C.
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (12/12 displayed)
- 2021Extreme Biomimetics: Designing of the First Nanostructured 3D Spongin–Atacamite Composite and its Applicationcitations
- 2020Microstructure-corrosion behaviour relationship of micro-alloyed Mg-0.5Zn alloy with the addition of Ca, Sr, Ag, In and Cucitations
- 2018Metal-Halide Perovskites for Gate Dielectrics in Field-Effect Transistors and Photodetectors Enabled by PMMA Lift-Off Processcitations
- 2017Oxide Thin-Film Electronics on Carbon Fiber Reinforced Polymer Compositecitations
- 2016Reduction of the elongation at break of thermoplastic polyolefins through melt blending with polylactide and the influence of the amount of compatibilizers and the viscosity ratios of the blend components on phase morphology and mechanicscitations
- 2016Metal oxide semiconductor thin-film transistors for flexible electronicscitations
- 2013In vitro and in vivo evaluation of biodegradable, open-porous scaffolds made of sintered magnesium W4 short fibrescitations
- 2012Ion release from magnesium materials in physiological solutions under different oxygen tensionscitations
- 2011Layered silicate epoxy nanocomposites: formation of the inorganic-carbonaceous fire protection layercitations
- 2011Corrosion of magnesium in static and dynamic (bioreactor) systems
- 2011Factors influencing magnesium corrosion in vitro - Environment, proteins and oxygen
- 2010Magnesium alloys as implant materials – Principles of property design for Mg–RE alloyscitations
Places of action
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article
In vitro and in vivo evaluation of biodegradable, open-porous scaffolds made of sintered magnesium W4 short fibres
Abstract
S.8611-8623 ; A cytocompatible and biocompatible, degradable, open-porous, mechanically adaptable metal scaffold made of magnesium alloy W4 melt-extracted short fibres was fabricated by liquid phase sintering. Cylindrical samples (3 × 5 mm) of sintered W4 short fibres were evaluated under in vitro (L929, HOB, eudiometer, weight loss) and in vivo conditions (rabbits: 6 and 12 weeks). The in vitro corrosion environment (e.g., temperature, flow, composition of corrosion solution, exposure time) significantly influenced the corrosion rates of W4 scaffolds compared with corrosion in vivo. Corrosion rates under cell culture conditions for 72 h varied from 1.05 to 3.43 mm y-1 depending on the media composition. Corrosion rates measured in eudiometric systems for 24 h were 24-27 times higher (3.88-4.43 mm y-1) than corrosion in vivo after 6 weeks (0.16 mm y-1). Moreover, it was found that the cell culture media composition significantly influences the ionic composition of the extract by sele ctively dissolving ions from W4 samples or their corrosion products. A pilot in vivo study for 6 and 12 weeks demonstrated active bone remodelling, no foreign body reaction and no clinical observation of gas formation during W4 scaffold implantation. Long-term in vivo studies need to be conducted to prove complete degradation of the W4 scaffold and total replacement by the host tissue. ; 9 ; Nr.10