| People | Locations | Statistics |
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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Howdle, Steven M.
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (16/16 displayed)
- 2024A facile one step route that introduces functionality to polymer powders for laser sinteringcitations
- 2023Modification of linear polyethylenimine with supercritical CO2 : from fluorescent materials to covalent cross-linkscitations
- 2022Antimicrobial ‘inks’ for 3D printing: block copolymer-silver nanoparticle composites synthesised using supercritical CO2citations
- 2021Amylose/cellulose nanofiber composites for all-natural, fully biodegradable and flexible bioplasticscitations
- 2020Starch/Poly(glycerol-adipate) Nanocomposites: A Novel Oral Drug Delivery Devicecitations
- 2020Low-temperature and purification-free stereocontrolled ring-opening polymerisation of lactide in supercritical carbon dioxidecitations
- 2019Hydrocarbon based stabilisers for the synthesis of cross-linked poly(2-hydroxyethyl methacrylate) particles in supercritical carbon dioxidecitations
- 2019Monitoring morphology evolution within block copolymer microparticles during dispersion polymerisation in supercritical carbon dioxidecitations
- 2014A high pressure cell for supercritical CO2 on-line chemical reactions studied with x-ray techniquescitations
- 2013Porous copolymers of ε-caprolactone as scaffolds for tissue engineeringcitations
- 2013Towards superhydrophobic coatings made by non-fluorinated polymers sprayed from a supercritical solutioncitations
- 2009Continuous flow supercritical chemical fluid deposition of optoelectronic quality CdScitations
- 2009Electrodeposition of metals from supercritical fluidscitations
- 2009Biocompatibility and osteogenic potential of human fetal femur-derived cells on surface selective laser sintered scaffoldscitations
- 2006Surface enhanced Raman scattering using metal modified microstructured optical fiber substratescitations
- 2006Surface enhanced Raman scattering using metal modified microstructured optical fibre substratescitations
Places of action
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article
Biocompatibility and osteogenic potential of human fetal femur-derived cells on surface selective laser sintered scaffolds
Abstract
For optimal bone regeneration, scaffolds need to fit anatomically into the requisite bone defects and, ideally, augment cell growth and differentiation. In this study we evaluated novel computationally designed surface selective laser sintering (SSLS) scaffolds for their biocompatibility as templates, in vitro and in vivo, for human fetal femur-derived cell viability, growth and osteogenesis. Fetal femur-derived cells were successfully cultured on SSLS-poly(d,l)-lactic acid (SSLS-PLA) scaffolds expressing alkaline phosphatase activity after 7 days. Cell proliferation, ingrowth, Alcian blue/Sirius red and type I collagen positive staining of matrix deposition were observed for fetal femur-derived cells cultured on SSLS-PLA scaffolds in vitro and in vivo. SSLS-PLA scaffolds and SSLS-PLA scaffolds seeded with fetal femur-derived cells implanted into a murine critical-sized femur segmental defect model aided the regeneration of the bone defect. SSLS techniques allow fabrication of biocompatible/biodegradable scaffolds, computationally designed to fit any defect, providing a template for cell osteogenesis in vitro and in vivo.