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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Ramadan, Marwa A.
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (6/6 displayed)
- 2024Reducing the effective dose of cisplatin using cobalt modified silver nano-hybrid as a carriers on MCF7 and HCT cell modelscitations
- 2024Laser photostability of chitosan coated gold-GO nanocomposite and its role as a nano-therapeutic agent for control breast cancer growthcitations
- 2024Antitumor efficiency and photostability of newly green synthesized silver/graphene oxide nanocomposite on different cancer cell linescitations
- 2024Laser enhanced photothermal effect of silver nanoparticles synthesized by chemical and green method on Gram-positive and Gram-negative bacteriacitations
- 2024Silver-graphene oxide nanocomposite doping chitosan/PVA membrane for arsenic (III) elimination from aqueous solutioncitations
- 2023Photostability, cytotoxicity, and photothermal impact of AgNPs, CoAgNC, and IOAgNC on HEp-2 laryngeal carcinoma cellscitations
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article
Laser photostability of chitosan coated gold-GO nanocomposite and its role as a nano-therapeutic agent for control breast cancer growth
Abstract
<jats:title>Abstract</jats:title><jats:sec><jats:title>Background</jats:title><jats:p>As the global cancer burden increases, it is critical to develop alternative treatments that produce minimal side effects, owing to its optical, thermal, and biological anticancer and biomedical applications of graphene and its nanocomposites. researchers have devoted the past few years to developing graphene/polymer and graphene/metal nanocomposites.</jats:p></jats:sec><jats:sec><jats:title>Materials and methods</jats:title><jats:p>Here a simple, highly stable, non-toxic, eco- friendly chitosan gold nanoparticles (Cs-AuNPs) and its nanocomposites with graphene oxide nanosheets (GO) to form novel photostable (GO/AuNPs) nanocomposites. The prepared nanomaterials were characterized by UV–Vis, FTIRs, TEM and Raman as shown in graphical abstract. In addition, the anticancer efficiency of the prepared nanomaterials in breast cell lines (MCF7, T47D, MDA-MB-468 and MDA-MB-231) using SRP assay were evaluated.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>Results revealed that Cs-AuNPs bound with the GO sheets via electrostatic interaction with high stability with uniform decoration. A new FTIRs peak of high intensity was found in the GO/Au nanocomposite confirming the decoration of Cs-AuNPs on the surface of the GO layers. GO/Au nanocomposite has a significant cytotoxic effect on breast cell lines as compared to GO only.</jats:p></jats:sec><jats:sec><jats:title>Conclusion</jats:title><jats:p>This work opens perceptions for translational applications of GO/Au nanocomposite on cancer cell lines, future work is to use the prepared nanocomposite in photothermal chemotherapy combined treatment.</jats:p></jats:sec><jats:sec><jats:title>Graphical abstract</jats:title></jats:sec>