| People | Locations | Statistics |
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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Romero, Luis Emerson Coy
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (35/35 displayed)
- 2019Enhanced electrocatalytic performance triggered by atomically bridged boron nitride between palladium nanoparticles and carbon fibers in gas-diffusion electrodescitations
- 2019Low-temperature growth of epitaxial Ti <inf>2</inf> AlC MAX phase thin films by low-rate layer-by-layer PVDcitations
- 2019Photoelectrochemically Active N-Adsorbing Ultrathin TiO <inf>2</inf> Layers for Water-Splitting Applications Prepared by Pyrolysis of Oleic Acid on Iron Oxide Nanoparticle Surfaces under Nitrogen Environmentcitations
- 2019Dendrimer based theranostic nanostructures for combined chemo- and photothermal therapy of liver cancer cells in vitrocitations
- 2019Effect of porous silicon substrate on structural, mechanical and optical properties of MOCVD and ALD ruthenium oxide nanolayerscitations
- 2019Multilayer design of crN/MoN superhard protective coatings and their characterisationcitations
- 2018Influence of ZnO/graphene nanolaminate periodicity on their structural and mechanical propertiescitations
- 2018Experimental and theoretical studies of the physicochemical and mechanical properties of multi-layered TiN/SiC films: Temperature effects on the nanocomposite structurecitations
- 2018Novel and Facile Route for the Synthesis of Tunable Boron Nitride Nanotubes Combining Atomic Layer Deposition and Annealing Processes for Water Purificationcitations
- 2018Synthesis of functional ceramic supports by ice templating and atomic layer depositioncitations
- 2018Structural and mechanical characterization of (TiZrNbHfTa)N/WN multilayered nitride coatingscitations
- 2018Cilostazol-Loaded Poly(ε-Caprolactone) Electrospun Drug Delivery System for Cardiovascular Applicationscitations
- 2018Microstructure, phase composition and mechanical properties of novel nanocomposite (TiAlSiY)N and nano-scale (TiAlSiY)N/MoN multifunctional heterostructurescitations
- 2018A new type of (TiZrNbTaHf)N/MoN nanocomposite coating: Microstructure and properties depending on energy of incident ionscitations
- 2018Cyclodextrin-based magnetic nanoparticles for cancer therapycitations
- 2018Nano-multilayered coatings of (TiAlSiY)N/MeN (Me=Mo, Cr and Zr): Influence of composition of the alternating layer on their structural and mechanical propertiescitations
- 2018Gel with silver and ultrasmall iron oxide nanoparticles produced with Amanita muscaria extract: physicochemical characterization, microstructure analysis and anticancer propertiescitations
- 2018High-temperature Magnetodielectric Bi (Fe0.5Mn0.5) O3 Thin Films with Checkerboard-Ordered Oxygen Vacancies and Low Magnetic Dampingcitations
- 2018ZnS coating for enhanced environmental stability and improved properties of ZnO thin filmscitations
- 2018Superhard CrN/MoN coatings with multilayer architecturecitations
- 2017Nanoscale Effects of Radiation (UV, X-ray, and γ) on Calcite Surfaces: Implications for its Mechanical and Physico-Chemical Propertiescitations
- 2017Release and cytotoxicity studies of magnetite/Ag/antibiotic nanoparticles: An interdependent relationshipcitations
- 2017Perpendicularly magnetized Co20Fe60B20 layer sandwiched between Au with low Gilbert dampingcitations
- 2017Mechanical properties of boron nitride thin films prepared by atomic layer depositioncitations
- 2017High Electrocatalytic Response of a Mechanically Enhanced NbC Nanocomposite Electrode Toward Hydrogen Evolution Reactioncitations
- 2017Boron Nitride Nanoporous Membranes with High Surface Charge by Atomic Layer Depositioncitations
- 2016Combined reactive/non-reactive DC magnetron sputtering of high temperature composite AlN-TiB <inf>2</inf> -TiSi <inf>2</inf>citations
- 2016Poly(ethylene oxide)-block-polystyrene thin films morphology controlled by drying conditions and substrate topographycitations
- 2016Enhancement of optical and mechanical properties of Si nanopillars by ALD TiO<inf>2</inf>coatingcitations
- 2016Gradient nanostructured coatings obtained by magnetron sputtering of a multiphase AlN–TiB<inf>2</inf>–TiSi<inf>2</inf> targetcitations
- 2016Fourier transform infrared and Raman spectroscopy studies on magnetite/Ag/antibiotic nanocompositescitations
- 2016Orientation dependent Ti diffusion in YNMO/STO thin films deposited by pulsed laser depositioncitations
- 2016High temperature behavior of functional TiAlBSiN nanocomposite coatingscitations
- 2015Tuning the photodynamic efficiency of TiO<inf>2</inf> nanotubes against HeLa cancer cells by Fe-dopingcitations
- 2014Facile synthesis of highly stable and water-soluble magnetic MWCNT/α-Fe nanocompositescitations
Places of action
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article
Cilostazol-Loaded Poly(ε-Caprolactone) Electrospun Drug Delivery System for Cardiovascular Applications
Abstract
<p>Purpose: The study discusses the value of electrospun cilostazol-loaded (CIL) polymer structures for potential vascular implant applications. Methods: Biodegradable polycaprolactone (PCL) fibers were produced by electrospinning on a rotating drum collector. Three different concentrations of CIL: 6.25%, 12.50% and 18.75% based on the amount of polymer, were incorporated into the fibers. The fibers were characterized by their size, shape and orientation. Materials characterization was carried out by Fourier Transformed Infrared spectroscopy (FTIR), Raman spectroscopy, differential scanning calorimetry (DSC) and X-ray diffraction (XRD). In vitro drug release study was conducted using flow-through cell apparatus (USP 4). Results: Three-dimensional structures characterized by fibers diameter ranging from 0.81 to 2.48 μm were in the range required for cardiovascular application. DSC and XRD confirmed the presence of CIL in the electrospun fibers. FTIR and Raman spectra confirmed CIL polymorphic form. Elastic modulus values for PCL and the CIL-loaded PCL fibers were in the range from 0.6 to 1.1 GPa. The in vitro release studies were conducted and revealed drug dissolution in combination with diffusion and polymer relaxation as mechanisms for CIL release from the polymer matrix. Conclusions: The release profile of CIL and nanomechanical properties of all formulations of PCL fibers demonstrate that the cilostazol loaded PCL fibers are an efficient delivery system for vascular implant application.</p>