| People | Locations | Statistics |
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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Cunha Silva, L.
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (11/11 displayed)
- 2021Multidimensional ln-aminophthalate photoluminescent coordination polymerscitations
- 2021Decorating MOF-74-derived nanocarbons with a sandwich-type polyoxometalate to enhance their OER activity: Exploring the underestimated bulk-deposition approachcitations
- 2020Advanced framework-modified POM@ZIF-67 nanocomposites as enhanced oxygen evolution reaction electrocatalystscitations
- 2020Oxygen Evolution Reaction Electrocatalytic Improvement in POM@ZIF Nanocomposites: A Bidirectional Synergistic Effectcitations
- 2019Synthesis of Pyridyl and N-Methylpyridinium Analogues of Rosamines: Relevance of Solvent and Charge on Their Photophysical Propertiescitations
- 2016Design of a Water Soluble Fluorescent 3-Hydroxy-4-Pyridinone Ligand Active at Physiological pH Valuescitations
- 2014Novel polyoxometalate silica nano-sized spheres: efficient catalysts for olefin oxidation and the deep desulfurization processcitations
- 2014Tuning the limits of pH interference of a rhodamine ion sensor by introducing catechol and 3-hydroxy-4-pyridinone chelating unitscitations
- 2013Novel Composite Material Polyoxovanadate@MIL-101(Cr): A Highly Efficient Electrocatalyst for Ascorbic Acid Oxidationcitations
- 2013Europium Polyoxometalates Encapsulated in Silica Nanoparticles Characterization and Photoluminescence Studiescitations
- 2010Insights into electronic and structural properties of novel Pd(II) salen-type complexescitations
Places of action
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article
Design of a Water Soluble Fluorescent 3-Hydroxy-4-Pyridinone Ligand Active at Physiological pH Values
Abstract
In the present work we report the structure and the spectroscopic characterization of a new fluorescent 3-hydroxy-4-pyridinone ligand D-3,4-HPO. The synthesis of the compound was performed in two steps, which involve the reaction of the commercially available fluorophore dansyl chloride with a 3-hydroxy-4-pyridinone chelating unit and further deprotection. The new fluorescent chelator was characterized in the solid state by single-crystal X-ray diffraction and in solution by NMR, MS, absorption and fluorescence spectroscopies. The analysis of the variation of the absorption spectrum with pH allowed the determination of four pK (a) values (pK (a1) = 3.50, pK (a2) = 4.50, pK (a3) = 9.60, pK (a4) = 10.20) and establishment of the corresponding distribution diagram. The study of the fluorescence properties of the ligand show that in the pH range between 4 and 9 the fluorescence intensity is constant and has its maximum value thus allowing its further use at physiological pH values. The interaction of the ligand with copper(II) was accessed by fluorescence spectroscopy in MOPS buffer and the results show that the presence of copper(II) quenches the fluorescence of the ligand in ca 94 % at a ligand: metal ratio of 2:1. The latter result is consistent with the formation of a copper(II) complex with the bidentate ligand, as confirmed by the EPR spectroscopy.