• Madej, Maria
• Kapica, Ryszard
• Tyczkowski, Jacek
• Baś, Bogusław
• Porada, Radosław
• Kochana, Jolanta
• Trzcińska, Agata
• Lipińska, Justyna
• Fronczak, Maciej

Abstract

<jats:title>Abstract</jats:title><jats:p> A original electrochemical sensing platform, based on screen-printed electrodes modification with plasma polymerized acrylonitrile (pp-AN) nanofilms is proposed. For that purpose, plasma-enhanced chemical vapor deposition (PECVD) process was conducted in a parallel plate (13.56 MHz) plasma reactor for 2 min with discharge power of 10 W. The surface topography and electrochemical properties of prepared sensors were investigated by X-ray photoelectron spectroscopy, scanning electron microscopy, energy dispersion spectroscopy, electrochemical impedance spectroscopy, and cyclic voltammetry. The electrochemical characteristics of pp-AN/SPCE and pp-AN/SPAuE sensors was investigated for model redox pair [Fe(CN)<jats:sub>6</jats:sub>]<jats:sup>4−/3−</jats:sup>. Conducted research confirmed the excellent chemical stability, durability, wide potential window, high signal-to-noise (S/N) ratio, and, most importantly, the ability to standardize the sensors. The pp-AN/SPCE sensor was applied to the determination of bupropion, an antidepressant drug whose intake has increased dramatically during the COVID-19 pandemic. The voltammetric response of pp-AN/SPCE for BUP was linear in two concentration ranges of 0.63–10.0 and 10.0–50.0 μmol L<jats:sup>−1</jats:sup>, with a detection limit of 0.21 μmol L<jats:sup>−1</jats:sup>. Satisfactory recoveries (96.2–102%) and good precision (RSD below 4.1%) obtained for environmental and biological samples confirmed the usefulness of the sensor for the analysis of various kinds of samples.</jats:p><jats:p><jats:bold>Graphical Abstract</jats:bold></jats:p>

Topics

• impedance spectroscopy
• dispersion
• surface
• Carbon
• scanning electron microscopy
• x-ray photoelectron spectroscopy
• chemical stability
• durability
• chemical vapor deposition
• cyclic voltammetry