Materials Map

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The Materials Map is an open tool for improving networking and interdisciplinary exchange within materials research. It enables cross-database search for cooperation and network partners and discovering of the research landscape.

The dashboard provides detailed information about the selected scientist, e.g. publications. The dashboard can be filtered and shows the relationship to co-authors in different diagrams. In addition, a link is provided to find contact information.

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in Cooperation with on an Cooperation-Score of 37%

Topics

Publications (2/2 displayed)

  • 2023Substitutional semi-rigid osteosynthesis technique for treatment of unstable pubic symphysis injuries: a biomechanical study2citations
  • 2023SAXS imaging reveals optimized osseointegration properties of bioengineered oriented 3D-PLGA/aCaP scaffolds in a critical size bone defect model.20citations

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Chart of shared publication
Pastor, Tatjana
1 / 1 shared
Grüneweller, Niklas
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Berk, Karlyn
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Berk, Till
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Schwarzenberg, Peter
1 / 1 shared
Gueorguiev, Boyko
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Richards, Geoff
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Halvachizadeh, Sascha
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Varga, Peter
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Zderic, Ivan
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Generali, Melanie
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Guizar-Sicairos, Manuel
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Groninger, Olivier
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Cinelli, Paolo
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Dominguez, Ana Perez
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Stark, Wendelin
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2023

Co-Authors (by relevance)

  • Pastor, Tatjana
  • Grüneweller, Niklas
  • Berk, Karlyn
  • Berk, Till
  • Schwarzenberg, Peter
  • Gueorguiev, Boyko
  • Richards, Geoff
  • Halvachizadeh, Sascha
  • Varga, Peter
  • Zderic, Ivan
  • Generali, Melanie
  • Guizar-Sicairos, Manuel
  • Groninger, Olivier
  • Tiziani, Simon
  • Neldner, Yvonne
  • Weber, Franz E.
  • Rodriguez-Palomo, Adrian
  • Casanova, Elisa A.
  • Arnke, Kevin
  • Stahli, Lisa
  • Nielsen, Leonard C.
  • Gao, Zirui
  • Liebi, Marianne
  • Cinelli, Paolo
  • Dominguez, Ana Perez
  • Appel, Christian
  • Stark, Wendelin
OrganizationsLocationPeople

article

Substitutional semi-rigid osteosynthesis technique for treatment of unstable pubic symphysis injuries: a biomechanical study

  • Pastor, Tatjana
  • Grüneweller, Niklas
  • Berk, Karlyn
  • Berk, Till
  • Schwarzenberg, Peter
  • Gueorguiev, Boyko
  • Richards, Geoff
  • Halvachizadeh, Sascha
  • Pape, Hans-Christoph
  • Varga, Peter
  • Zderic, Ivan
Abstract

<jats:title>Abstract</jats:title><jats:sec><jats:title>Background/Purpose</jats:title><jats:p>The surgical fixation of a symphyseal diastasis in partially or fully unstable pelvic ring injuries is an important element when stabilizing the anterior pelvic ring. Currently, open reduction and internal fixation (ORIF) by means of plating represents the gold standard treatment. Advances in percutaneous fixation techniques have shown improvements in blood loss, surgery time, and scar length. Therefore, this approach should also be adopted for treatment of symphyseal injuries. The technique could be important since failure rates, following ORIF at the symphysis, remain unacceptably high. The aim of this biomechanical study was to assess a semi-rigid fixation technique for treatment of such anterior pelvic ring injuries versus current gold standards of plate osteosynthesis.</jats:p></jats:sec><jats:sec><jats:title>Methods</jats:title><jats:p>An anterior pelvic ring injury type III APC according to the Young and Burgess classification was simulated in eighteen composite pelvises, assigned to three groups (<jats:italic>n</jats:italic> = 6) for fixation with either a single plate, two orthogonally positioned plates, or the semi-rigid technique using an endobutton suture implant. Biomechanical testing was performed in a simulated upright standing position under progressively increasing cyclic loading at 2 Hz until failure or over 150,000 cycles. Relative movements between the bone segments were captured by motion tracking.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>Initial quasi-static and dynamic stiffness, as well as dynamic stiffness after 100,000 cycles, was not significantly different among the fixation techniques (<jats:italic>p</jats:italic> ≥ 0.054).). The outcome measures for total displacement after 20,000, 40,000, 60,000, 80,000, and 100,000 cycles were associated with significantly higher values for the suture technique versus double plating (<jats:italic>p</jats:italic> = 0.025), without further significant differences among the techniques (<jats:italic>p</jats:italic> ≥ 0.349). Number of cycles to failure and load at failure were highest for double plating (150,000 ± 0/100.0 ± 0.0 N), followed by single plating (132,282 ± 20,465/91.1 ± 10.2 N), and the suture technique (116,088 ± 12,169/83.0 ± 6.1 N), with significantly lower values in the latter compared to the former (<jats:italic>p</jats:italic> = 0.002) and no further significant differences among the techniques (<jats:italic>p</jats:italic> ≥ 0.329).</jats:p></jats:sec><jats:sec><jats:title>Conclusion</jats:title><jats:p>From a biomechanical perspective, the semi-rigid technique for fixation of unstable pubic symphysis injuries demonstrated promising results with moderate to inferior behaviour compared to standard plating techniques regarding stiffness, cycles to failure and load at failure. This knowledge could lay the foundation for realization of further studies with larger sample sizes, focusing on the stabilization of the anterior pelvic ring.</jats:p></jats:sec>

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