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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Khalid, Mohammad
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (13/13 displayed)
- 2024Influence of Dilution Upon the Ultraviolet-Visible Peak Absorbance and Optical Bandgap Estimation of Tin(IV) Oxide and Tin(IV) Oxide-Molybdenum(IV) Sulfide Solutionscitations
- 2023Facile and Affordable Design of MXene‐Co<sub>3</sub>O<sub>4</sub>‐Based Nanocomposites for Detection of Hydrogen Peroxide in Cancer Cells: Toward Portable Tool for Cancer Managementcitations
- 2023Impacts of annealing temperature and time on the thermoelectric performance of recycled carbon fiber (RCF)/n-Bi2Te3 heterostructure thermoelectric composites.
- 2022Internet-of-nano-things (IoNT) driven intelligent face masks to combat airborne health hazard
- 2022Internet-of-nano-things (IoNT) driven intelligent face masks to combat airborne health hazardcitations
- 2022Tailoring crystallinity of 2D cobalt phosphate to introduce pseudocapacitive behaviorcitations
- 2022Comprehensive review on carbon nanotubes embedded in different metal and polymer matrix: fabrications and applicationscitations
- 2022Microwave assisted synthesis of Mn3O4 nanograins intercalated into reduced graphene oxide layers as cathode material for alternative clean power generation energy devicecitations
- 2022Development of Dapagliflozin Solid Lipid Nanoparticles as a Novel Carrier for Oral Delivery: Statistical Design, Optimization, In-Vitro and In-Vivo Characterization, and Evaluationcitations
- 2022Three-Dimensional Graphene-TiO2-SnO2Ternary Nanocomposites for High-Performance Asymmetric Supercapacitorscitations
- 2022Emergence of MXene–olymer hybrid nanocomposites as high-performance next-generation chemiresistors for efficient air quality monitoringcitations
- 2021Comprehensive review on carbon nanotubes embedded in different metal and polymer matrix: fabrications and applicationscitations
- 2019Effective devulcanization of ground tire rubber using choline chloride-based deep eutectic solventscitations
Places of action
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article
Facile and Affordable Design of MXene‐Co<sub>3</sub>O<sub>4</sub>‐Based Nanocomposites for Detection of Hydrogen Peroxide in Cancer Cells: Toward Portable Tool for Cancer Management
Abstract
<jats:title>Abstract</jats:title><jats:p>Hydrogen peroxide (H<jats:sub>2</jats:sub>O<jats:sub>2</jats:sub>) is a primary reactive oxygen species (ROS) that can act as a chemical signal in developing and progressing serious and life‐threatening diseases like cancer. Due to the stressful nature of H<jats:sub>2</jats:sub>O<jats:sub>2</jats:sub>, there is an urgent need to develop sensitive analytical approaches to be applied to various biological matrices. Herein, a portable point‐of‐care electrochemical system based on MXene‐Co<jats:sub>3</jats:sub>O<jats:sub>4</jats:sub> nanocomposites to detect H<jats:sub>2</jats:sub>O<jats:sub>2</jats:sub> in different cancer cell‐lines is presented. The developed sensor is affordable, disposable, and highly selective for H<jats:sub>2</jats:sub>O<jats:sub>2</jats:sub> detection. This approach achieves a dynamic linear range of 75 µm with a LOD of 0.5 µ<jats:sc>m</jats:sc> and a LOQ of 1.6 µ<jats:sc>m</jats:sc>. To improve the practical application, the level of ROS is evaluated both in cancer cell lines MDA‐MB‐231 and DU145, respectively, to breast and prostate cancers, and in healthy HaCat cells. Moreover, the same cancer cells are treated with transforming growth factor‐β1, and MXene‐Co<jats:sub>3</jats:sub>O<jats:sub>4</jats:sub> modified strip is capable to monitorROS variation. The results are satisfactory compared with the cellular ROS fluorescent assay based on DCFH/DCFH‐DA. These results open new perspectives for real‐time monitoring of cancer progression and the efficacy of the therapy.</jats:p>